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Vitellogenin Induction and Increased Plasma 17β-Estradiol Concentrations in Male Nile Tilapia, Oreochromis niloticus, Exposed to Organochlorine Pollutants and Polycyclic Aromatics Hydrocarbons

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Abstract

Vitellogenin (Vtg), 17β-estradiol (E2) and testosterone (T) were used as biomarkers of endocrine disruption in mature male nile tilapia (Oreochromis niloticus) from three lakes (Rio, Enmedio and Limon) in Chiapas, Mexico. Vitellogenesis induction was found in tilapias from Rio and Limon, moderately high E2 levels in Rio and Limon tilapias, compared with controls (cultured tilapias). Significant correlations between benzo(a)pyrene (BaP) metabolites and hexachlorobenzene (HCB) with Vtg and E2 were found. The results of this study indicate that endocrine disruption exists in tilapias from Rio and Limon lakes, and that exposure to HCB and BaP could be causing these alterations.

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Acknowledgments

The authors wish to thank PEMEX (Producción y Exploración, Refinación, y Petroquímica) for financial support, to Dr. Rene Capurro Filograsso for revising an earlier version, and to Jorge Dominguez Maldonado for his technical assistance.

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  1. CINVESTAV Unidad Mérida, Km. 6 Antigua Carretera a Progreso, Mérida, Yucatán, CP 97310, México

    Juan Pablo Rodas-Ortíz, Victor Ceja-Moreno, Maria Eulalia Chan-Cocom & Gerardo Gold-Bouchot

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  1. Juan Pablo Rodas-Ortíz
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  2. Victor Ceja-Moreno
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  3. Maria Eulalia Chan-Cocom
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  4. Gerardo Gold-Bouchot
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Correspondence to Gerardo Gold-Bouchot.

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Rodas-Ortíz, J.P., Ceja-Moreno, V., Chan-Cocom, M.E. et al. Vitellogenin Induction and Increased Plasma 17β-Estradiol Concentrations in Male Nile Tilapia, Oreochromis niloticus, Exposed to Organochlorine Pollutants and Polycyclic Aromatics Hydrocarbons. Bull Environ Contam Toxicol 81, 543–547 (2008). https://doi.org/10.1007/s00128-008-9556-9

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  • DOI: https://doi.org/10.1007/s00128-008-9556-9

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