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Bioelectroanalysis with nanoelectrode ensembles and arrays

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Abstract

This review deals with recent advances in bioelectroanalytical applications of nanostructured electrodes, in particular nanoelectrode ensembles (NEEs) and arrays (NEAs). First, nanofabrication techniques, principles of function, and specific advantages and limits of NEEs and NEAs are critically discussed. In the second part, some recent examples of bioelectroanalytical applications are presented. These include use of nanoelectrode arrays and/or ensembles for direct electrochemical analysis of pharmacologically active organic compounds or redox proteins, and the development of functionalized nanoelectrode systems and their use as catalytic or affinity electrochemical biosensors.

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Acknowledgments

The authors would like to thank MIUR (Rome) (project: PRIN 2008MWHCP2) for partial financial support.

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  1. Department of Molecular Sciences and Nanosystems, University Ca’ Foscari of Venice, S. Marta 2137, 30123, Venice, Italy

    Michael Ongaro & Paolo Ugo

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  1. Michael Ongaro
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Correspondence to Paolo Ugo.

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Published in the topical collection Bioelectroanalysis with guest editors Nicolas Plumeré, Magdalena Gebala, and Wolfgang Schuhmann

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Ongaro, M., Ugo, P. Bioelectroanalysis with nanoelectrode ensembles and arrays. Anal Bioanal Chem 405, 3715–3729 (2013). https://doi.org/10.1007/s00216-012-6552-z

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