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The effect of shock wave lithotripsy and retrograde intrarenal surgery on health-related quality of life in 10–20 mm renal stones: a prospective randomized pilot study

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Abstract

The effects of treatment modalities such as retrograde intrarenal surgery (RIRS) and shock wave lithotripsy (SWL) on health-related quality of life (HRQoL) were determined in patients with renal stones between 10 and 20 mm. A total of 120 patients were included in the study and prospectively randomized to RIRS or SWL group. A total of 39 patients experienced treatment failure and finally 81 patients (45 patients in the RIRS group, 36 patients in the SWL group) were analyzed for HRQoL. SF-36 survey was used to determine HRQoL pre-operatively, post-operative day 1 and 1 month. The patient and stone characteristics such as age, gender, stone size, grade of hydronephrosis and body mass index were similar between the two groups. At post-operative day 1, the RIRS group was associated with lower scores of role functioning/physical (p = 0.008), role functioning/emotional (p = 0.047) energy/fatigue (p = 0.011), social functioning (p = 0.003) and pain (p = 0.003) when compared to the SWL group. At post-operative 1 month, only pain and emotional well-being scores (p = 0.012 and p = 0.011, respectively) in the RIRS group were statistically lower according to the SWL group. In our study, patients in the SWL group showed more favorable HRQoL scores when compared to the patients in the RIRS group in short-term follow-up.

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Authors

Contributions

Atis G: project development, data management, manuscript editing. Culpan M: protocol development, data management, manuscript writing. Ucar T: data management and analysis. Sendogan F: data collection. Kazan HO: data collection. CYildirim A: project and protocol development.

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Correspondence to Meftun Culpan.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Atis, G., Culpan, M., Ucar, T. et al. The effect of shock wave lithotripsy and retrograde intrarenal surgery on health-related quality of life in 10–20 mm renal stones: a prospective randomized pilot study. Urolithiasis 49, 247–253 (2021). https://doi.org/10.1007/s00240-020-01219-1

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