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Weedy lignocellulosic feedstock and microbial metabolic engineering: advancing the generation of ‘Biofuel’

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Abstract

Lignocellulosic materials are the most abundant renewable organic resources (~200 billion tons annually) on earth that are readily available for conversion to ethanol and other value-added products, but they have not yet been tapped for the commercial production of fuel ethanol. The lignocellulosic substrates include woody substrates such as hardwood (birch and aspen, etc.) and softwood (spruce and pine, etc.), agro residues (wheat straw, sugarcane bagasse, corn stover, etc.), dedicated energy crops (switch grass, and Miscanthus etc.), weedy materials (Eicchornia crassipes, Lantana camara etc.), and municipal solid waste (food and kitchen waste, etc.). Despite the success achieved in the laboratory, there are limitations to success with lignocellulosic substrates on a commercial scale. The future of lignocellulosics is expected to lie in improvements of plant biomass, metabolic engineering of ethanol, and cellulolytic enzyme-producing microorganisms, fullest exploitation of weed materials, and process integration of the individual steps involved in bioethanol production. Issues related to the chemical composition of various weedy raw substrates for bioethanol formation, including chemical composition-based structural hydrolysis of the substrate, need special attention. This area could be opened up further by exploring genetically modified metabolic engineering routes in weedy materials and in biocatalysts that would make the production of bioethanol more efficient.

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  1. Anuj K. Chandel

    Present address: USP Escola de Engenharia de Lorena Estrada Municipal do Campinho–Caixa, Departamento de Biotecnologia Universidade de São Paulo, 116 12.602.810, Lorena, Sao Paolo, Brasil

Authors and Affiliations

  1. Centre for Biotechnology, Jawaharlal Nehru Technological University, Hyderabad, 500 085, India

    Anuj K. Chandel

  2. Division of Biological and Health Sciences, University of Pittsburgh, Bradford, PA, 16701, USA

    Om V. Singh

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  1. Anuj K. Chandel
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  2. Om V. Singh
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Correspondence to Om V. Singh.

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Chandel, A.K., Singh, O.V. Weedy lignocellulosic feedstock and microbial metabolic engineering: advancing the generation of ‘Biofuel’. Appl Microbiol Biotechnol 89, 1289–1303 (2011). https://doi.org/10.1007/s00253-010-3057-6

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  • DOI: https://doi.org/10.1007/s00253-010-3057-6

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