Skip to main content
SpringerLink
Log in

Streptomyces spp. in the biocatalysis toolbox

  • Mini-Review
  • Published:
Applied Microbiology and Biotechnology Aims and scope Submit manuscript

Abstract

About 20,100 research publications dated 2000–2017 were recovered searching the PubMed and Web of Science databases for Streptomyces, which are the richest known source of bioactive molecules. However, these bacteria with versatile metabolism are powerful suppliers of biocatalytic tools (enzymes) for advanced biotechnological applications such as green chemical transformations and biopharmaceutical and biofuel production. The recent technological advances, especially in DNA sequencing coupled with computational tools for protein functional and structural prediction, and the improved access to microbial diversity enabled the easier access to enzymes and the ability to engineer them to suit a wider range of biotechnological processes. The major driver behind a dramatic increase in the utilization of biocatalysis is sustainable development and the shift toward bioeconomy that will, in accordance to the UN policy agenda “Bioeconomy to 2030,” become a global effort in the near future. Streptomyces spp. already play a significant role among industrial microorganisms. The intention of this minireview is to highlight the presence of Streptomyces in the toolbox of biocatalysis and to give an overview of the most important advances in novel biocatalyst discovery and applications. Judging by the steady increase in a number of recent references (228 for the 2000–2017 period), it is clear that biocatalysts from Streptomyces spp. hold promises in terms of valuable properties and applicative industrial potential.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  • Adams AS, Jordan MS, Adams SM, Suen G, Goodwin LA, Davenport KW, Currie CR, Raffa KF (2011) Cellulose-degrading bacteria associated with the invasive woodwasp Sirex noctilio. ISME J 5(8):1323–1331

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Akanuma G, Hara H, Ohnishi Y, Horinouchi S (2009) Dynamic changes in the extracellular proteome caused by absence of a pleiotropic regulator AdpA in Streptomyces griseus. Mol Microbiol 73(5):898–912

    Article  CAS  PubMed  Google Scholar 

  • Alani F, Anderson WA, Moo-Young M (2008) New isolate of Streptomyces sp. with novel thermoalkalotolerant cellulases. Biotechnol Lett 30(1):123–126

    Article  CAS  PubMed  Google Scholar 

  • Allen AD, Anderson WA, Ayorinde F, Eribo BE (2011) Isolation and characterization of an extracellular thermoalkanophilic P(3HB-co-3HV) depolymerase from Streptomyces sp. IN1. Int Biodet Biodeg 65(6):777–785

    Article  CAS  Google Scholar 

  • Amore A, Pepe O, Ventorino V, Birolo L, Giangrande C, Faraco V (2012) Cloning and recombinant expression of a cellulase from the cellulolytic strain Streptomyces sp. G12 isolated from compost. Microb Cell Factories 11:164

    Article  CAS  Google Scholar 

  • Antonopoulos VT, Hernandez M, Arias ME, Mavrakos E, Ball AS (2001a) The use of extracellular enzymes from Streptomyces albus ATCC 3005 for the bleaching of eucalyptus kraft pulp. Appl Microbiol Biotechnol 57(1–2):92–97

    CAS  PubMed  Google Scholar 

  • Antonopoulos VT, Rob A, Ball AS, Wilson MT (2001b) Dechlorination of chlorophenols using extracellular peroxidases produced by Streptomyces albus ATCC 3005. Enzym Microb Technol 29(1):62–69

    Article  CAS  Google Scholar 

  • Antoraz S, Santamaria RI, Diaz M, Sanz D, Rodriguez H (2015) Toward a new focus in antibiotic and drug discovery from the Streptomyces arsenal. Front Microbiol 6:461

    Article  PubMed  PubMed Central  Google Scholar 

  • Arias ME, Arenas M, Rodriguez J, Soliveri J, Ball AS, Hernandez M (2003) Kraft pulp biobleaching and mediated oxidation of a nonphenolic substrate by laccase from Streptomyces cyaneus CECT 3335. Appl Environ Microbiol 69(4):1953–1958

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Arisawa A, Matsufuji M, Nakashima T, Dobashi K, Isshiki K, Yoshioka T, Yamada S, Momose H, Taguchi S (2002) Streptomyces serine protease (DHP-A) as a new biocatalyst capable of forming chiral intermediates of 1,4-dihydropyridine calcium antagonists. Appl Environ Microbiol 68(6):2716–2725

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ayaz B, Ugur A, Boran R (2015) Purification and characterization of organic solvent-tolerant lipase from Streptomyces sp. OC119-7 for biodiesel production. Biocatal Agri Biotechnol 4(1):103–108

    Google Scholar 

  • Bajaj BK, Sharma P (2011) An alkali-thermotolerant extracellular protease from a newly isolated Streptomyces sp. DP2. New Biotechnol 28(6):725–732

    Article  CAS  Google Scholar 

  • Baltz RH, Hegeman G, Skatrud PL (1993) Industrial microorganisms: basic and applied molecular genetics. American Society for Microbiology, Washington DC

    Google Scholar 

  • Battaini G, Monzani E, Casella L, Lonardi E, Tepper AW, Canters GW, Bubacco L (2002) Tyrosinase-catalyzed oxidation of fluorophenols. J Biol Chem 277(47):44606–44612

    Article  CAS  PubMed  Google Scholar 

  • Becker J, Wittmann C (2015) Advanced biotechnology: Metabolically engineered cells for the bio-based production of chemicals and fuels, materials, and health-care products. Angew Chemie Int Ed 54(11):3328–3350

    Article  CAS  Google Scholar 

  • Beg QK, Bhushan B, Kapoor M, Hoondal GS (2000) Production and characterization of thermostable xylanase and pectinase from Streptomyces sp. QG-11-3. J Ind Microbiol Biotechnol 24(6):396–402

    Article  CAS  Google Scholar 

  • Ben Elhoul M, Zarai Jaouadi N, Rekik H, Bejar W, Boulkour Touioui S, Hmidi M, Badis A, Bejar S, Jaouadi B (2015) A novel detergent-stable solvent-tolerant serine thiol alkaline protease from Streptomyces koyangensis TN650. Int J Biol Macromol 79:871–882

    Article  CAS  PubMed  Google Scholar 

  • Ben Hlima H, Bejar S, Riguet J, Haser R, Aghajari N (2013) Identification of critical residues for the activity and thermostability of Streptomyces sp. SK glucose isomerase. Appl Microbiol Biotechnol 97(22):9715–9726

    Article  CAS  PubMed  Google Scholar 

  • Bentley SD, Chater KF, Cerdeno-Tarraga AM, Challis GL, Thomson NR, James KD, Harris DE, Quail MA, Kieser H, Harper D, Bateman A, Brown S, Chandra G, Chen CW, Collins M, Cronin A, Fraser A, Goble A, Hidalgo J, Hornsby T, Howarth S, Huang CH, Kieser T, Larke L, Murphy L, Oliver K, O'Neil S, Rabbinowitsch E, Rajandream MA, Rutherford K, Rutter S, Seeger K, Saunders D, Sharp S, Squares R, Squares S, Taylor K, Warren T, Wietzorrek A, Woodward J, Barrell BG, Parkhill J, Hopwood DA (2002) Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 417(6885):141–147

    Article  PubMed  Google Scholar 

  • Binter A, Oberdorfer G, Hofzumahaus S, Nerstheimer S, Altenbacher G, Gruber K, Macheroux P (2011) Characterization of the PLP-dependent aminotransferase NikK from Streptomyces tendae and its putative role in nikkomycin biosynthesis. FEBS J 278(21):4122–3415

    Article  CAS  PubMed  Google Scholar 

  • Blamey JM, Fischer F, Meyer H-P, Sarmiento F, Zinn M (2017) Enzymatic biocatalysis in chemical transformations: a promising and emerging field in green chemistry practice. In: Brahmachari G, Demain AL, Adrio JL (eds) Biotechnology of microbial enzymes. Academic, Tokyo, pp 347–403

  • Book AJ, Lewin GR, McDonald BR, Takasuka TE, Wendt-Pienkowski E, Doering DT, Suh S, Raffa KF, Fox BG, Currie CR (2016) Evolution of high cellulolytic activity in symbiotic Streptomyces through selection of expanded gene content and coordinated gene expression. PLoS Biol 14(6):e1002475

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Bornscheuer UT (2018) The fourth wave of biocatalysis is approaching. Philos Trans Ser A, Mathematical, Physical, and Engineering Sciences 376 (2110)

  • Bornscheuer UT, Huisman GW, Kazlauskas RJ, Lutz S, Moore JC, Robins K (2012) Engineering the third wave of biocatalysis. Nature 485(7397):185–194

    Article  CAS  PubMed  Google Scholar 

  • Borrelli GM, Trono D (2015) Recombinant lipases and phospholipases and their use as biocatalysts for industrial applications. Int J Mol Sci 16(9):20774–20840

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Brahmachari G (2017) Lipase-catalyzed organic transformations: a recent update. In: Brahmachari G, Demain AL, Adrio JL (eds) Biotechnology of microbial enzymes. Academic, New York, pp 325–346

    Chapter  Google Scholar 

  • Brault G, Shareck F, Hurtubise Y, Lepine F, Doucet N (2012) Isolation and characterization of EstC, a new cold-active esterase from Streptomyces coelicolor A3(2). PLoS One 7(3):e32041

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Budihal SR, Agsar D, Patil SR (2016) Enhanced production and application of acidothermophilic Streptomyces cellulase. Bioresour Technol 200:706–712

    Article  CAS  PubMed  Google Scholar 

  • Burgie ES, Thoden JB, Holden HM (2007) Molecular architecture of DesV from Streptomyces venezuelae: a PLP-dependent transaminase involved in the biosynthesis of the unusual sugar desosamine. Protein Sci 16(5):887–896

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Calabia BP, Tokiwa Y (2006) A novel PHB depolymerase from a thermophilic Streptomyces sp. Biotechnol Lett 28(6):383–388

    Article  CAS  PubMed  Google Scholar 

  • Chater KF (2006) Streptomyces inside-out: a new perspective on the bacteria that provide us with antibiotics. Philos Trans Series B, Biol Sci 361(1469):761–768

    Article  CAS  Google Scholar 

  • Chater KF (2016) Recent advances in understanding Streptomyces. F1000. Research 5:2795

    Google Scholar 

  • Chater KF, Biro S, Lee KJ, Palmer T, Schrempf H (2010) The complex extracellular biology of Streptomyces. FEMS Microbiol Rev 34(2):171–198

    Article  CAS  PubMed  Google Scholar 

  • Chen R, Liao L, Zhang X, Chen B (2014) Cloning and analysis of a halogenase gene of Streptomyces sp. 604F from the Arctic Ocean. Wei Sheng Wu Xue Bao /Acta Microbiol Sin 54(6):703–712

    CAS  Google Scholar 

  • Chiang CM, Ding HY, Tsai YT, Chang TS (2015) Production of two novel methoxy-isoflavones from biotransformation of 8-hydroxydaidzein by recombinant Escherichia coli expressing O-methyltransferase SpOMT2884 from Streptomyces peucetius. Int J Mol Sci 16(11):27816–27823

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Cho SS, Park DJ, Simkhada JR, Hong JH, Sohng JK, Lee OH, Yoo JC (2012) A neutral lipase applicable in biodiesel production from a newly isolated Streptomyces sp. CS326. Bioprocess Biosyst Eng 35(1–2):227–234

    Article  CAS  PubMed  Google Scholar 

  • Choi JM, Han SS, Kim HS (2015) Industrial applications of enzyme biocatalysis: current status and future aspects. Biotechnol Adv 33(7):1443–1454

    Article  CAS  PubMed  Google Scholar 

  • Choojit S, Bornscheuer UT, Upaichit A, H-Kittikun A (2016) Efficient phosphatidylserine synthesis by a phospholipase D from Streptomyces sp. SC734 isolated from soil-contaminated palm oil. Eur J Lipid Sci Technol 118:803–813

    Article  CAS  Google Scholar 

  • Chou WK, Fanizza I, Uchiyama T, Komatsu M, Ikeda H, Cane DE (2010) Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol. JACS 132(26):8850–8851

    Article  CAS  Google Scholar 

  • Chovancova E, Pavelka A, Benes P, Strnad O, Brezovsky J, Kozlikova B, Gora A, Sustr V, Klvana M, Medek P, Biedermannova L, Sochor J, Damborsky J (2012) CAVER 3.0: a tool for the analysis of transport pathways in dynamic protein structures. PLOS Comp Biol 8(10):e1002708

    Article  CAS  Google Scholar 

  • Chu LL, Pandey RP, Lim HN, Jung HJ, Thuan NH, Kim T-S, Sohng JK (2017) Synthesis of umbelliferone derivatives in Escherichia coli and their biological activities. J Biol Eng 11(1):15

    Article  PubMed  PubMed Central  Google Scholar 

  • Chun YJ, Shimada T, Waterman MR, Guengerich FP (2006) Understanding electron transport systems of Streptomyces cytochrome P450. Biochem Soc Trans 34(Pt 6):1183–1185

    Article  CAS  PubMed  Google Scholar 

  • Cuozzo SA, Sineli PE, Davila Costa J, Tortella G (2017) Streptomyces sp. is a powerful biotechnological tool for the biodegradation of HCH isomers: biochemical and molecular basis. Crit Rev Biotechnol. https://doi.org/10.1080/07388551.2017.1398133

  • Damnjanovic J, Kuroiwa C, Tanaka H, Ishida K, Nakano H, Iwasaki Y (2016) Directing positional specificity in enzymatic synthesis of bioactive 1-phosphatidylinositol by protein engineering of a phospholipase D. Biotechnol Bioeng 113:62–71

    Article  CAS  PubMed  Google Scholar 

  • Davies J (2011) Streptomycetes are special: arcane applications. Microb Biotechnol 4(2):141–143

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • de Gonzalo G, Colpa DI, Habib MHM, Fraaije MW (2016) Bacterial enzymes involved in lignin degradation. J Biotechnol 236:110–119

    Article  PubMed  CAS  Google Scholar 

  • Deng H, Ma L, Bandaranayaka N, Qin Z, Mann G, Kyeremeh K, Yu Y, Shepherd T, Naismith JH, O'Hagan D (2014) Identification of fluorinases from Streptomyces sp MA37, Norcardia brasiliensis, and Actinoplanes sp N902-109 by genome mining. Chembiochem 15(3):364–368

    Article  CAS  PubMed  Google Scholar 

  • Dhar K, Rosazza JP (2000) Purification and characterization of Streptomyces griseus catechol O-methyltransferase. Appl Environ Microbiol 66(11):4877–4882

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dolashki A, Gushterova A, Voelter W, Tchorbanov B (2009) Purification and characterization of tyrosinases from Streptomyces albus. J Biosci 64(9–10):724–732

    CAS  Google Scholar 

  • Donadio S, Maffioli S, Monciardini P, Sosio M, Jabes D (2010) Sources of novel antibiotics—aside the common roads. Appl Microbiol Biotechnol 88(6):1261–1267

    Article  CAS  PubMed  Google Scholar 

  • Dos Santos JB, da Silva Cruz RG, Tardioli PW (2017) Production of whole-cell lipase from Streptomyces clavuligerus in a bench-scale bioreactor and its first evaluation as biocatalyst for synthesis in organic medium. Appl Biochem Biotechnol. https://doi.org/10.1007/s12010-017-2440-5

  • Dube E, Shareck F, Hurtubise Y, Beauregard M, Daneault C (2008a) Decolourization of recalcitrant dyes with a laccase from Streptomyces coelicolor under alkaline conditions. J Ind Microbiol Biotechnol 35(10):1123–1129

    Article  CAS  PubMed  Google Scholar 

  • Dube E, Shareck F, Hurtubise Y, Daneault C, Beauregard M (2008b) Homologous cloning, expression, and characterisation of a laccase from Streptomyces coelicolor and enzymatic decolourisation of an indigo dye. Appl Microbiol Biotechnol 79(4):597–603

    Article  CAS  PubMed  Google Scholar 

  • Ece S, Lambertz C, Fischer R, Commandeur U (2017) Heterologous expression of a Streptomyces cyaneus laccase for biomass modification applications. AMB Express 7(1):86

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • El-Sersy NA, Abd-Elnaby H, Abou-Elela GM, Ibrahim HA, El-Toukhy NM (2010) Optimization, economization and characterization of cellulase produced by marine Streptomyces ruber. Afr J Biotechnol 9(38):6355–6364

    CAS  Google Scholar 

  • Endo K, Hayashi Y, Hibi T, Hosono K, Beppu T, Ueda K (2003) Enzymological characterization of EpoA, a laccase-like phenol oxidase produced by Streptomyces griseus. J Biochem 133(5):671–677

    Article  CAS  PubMed  Google Scholar 

  • Enkhbaatar B, Lee CR, Hong YS, Hong SK (2016) Molecular characterization of xylobiose- and xylopentaose-producing beta-1,4-endoxylanase SCO5931 from Streptomyces coelicolor A3(2). Appl Biochem Biotechnol 180(2):349–360

    Article  CAS  PubMed  Google Scholar 

  • Fang Z, Yong YC, Zhang J, Du G, Chen J (2017) Keratinolytic protease: a green biocatalyst for leather industry. Appl Microbiol Biotechnol 101(21):7771–7779

    Article  CAS  PubMed  Google Scholar 

  • Fen W, Gerard H, Jones L, Osman S, Moreau R (1994) Production of cutin-degrading enzymes by plant pathogenic bacteria. Plant Pathogenic Bacteria: 641

  • Feng H, Zhang D, Sun Y, Zhi Y, Mao L, Luo Y, Xu L, Wang L, Zhou P (2015) Expression and characterization of a recombinant laccase with alkalistable and thermostable properties from Streptomyces griseorubens JSD-1. Appl Biochem Biotechnol 176(2):547–562

    Article  CAS  PubMed  Google Scholar 

  • Fett WF, Gérard HC, Moreau RA, Osman SF, Jones LE (1992) Cutinase production by Streptomyces spp. Curr Microbiol 25(3):165–171

    Article  CAS  Google Scholar 

  • Gangoiti J, Santos M, Prieto MA, de la Mata I, Serra JL, Llama MJ (2012) Characterization of a novel subgroup of extracellular medium-chain-length polyhydroxyalkanoate depolymerases from actinobacteria. Appl Environ Microbiol 78(20):7229–7237

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Garcia-Hidalgo J, Hormigo D, Prieto MA, Arroyo M, de la Mata I (2012) Extracellular production of Streptomyces exfoliatus poly(3-hydroxybutyrate) depolymerase in Rhodococcus sp. T104: determination of optimal biocatalyst conditions. Appl Microbiol Biotechnol 93(5):1975–1988

    Article  CAS  PubMed  Google Scholar 

  • García-Hidalgo J, Acebal C, de la Mata I, Arroyo M (2017) Developing an efficient strategy for immobilization of PHB depolymerase on magnetite-based nanoparticles for degrading polyhydroxybutyrate in acidic conditions. Biocatal Biotrensf. https://doi.org/10.1080/10242422.2017.1315942

  • Gavrish E, Bollmann A, Epstein S, Lewis K (2008) A trap for in situ cultivation of filamentous actinobacteria. J Microbiol Meth 72(3):257–262

    Article  CAS  Google Scholar 

  • Gottschalk LM, Bon EP, Nobrega R (2008) Lignin peroxidase from Streptomyces viridosporus T7A: enzyme concentration using ultrafiltration. Appl Biochem Biotechnol 147(1–3):23–32

    Article  CAS  PubMed  Google Scholar 

  • Grigorevski de Lima AL, Pires do Nascimento R, da Silva Bon EP, Coelho RRR (2005) Streptomyces drozdowiczii cellulase production using agro-industrial by-products and its potential use in the detergent and textile industries. Enzym Microb Technol 37(2):272–277

    Article  CAS  Google Scholar 

  • Gudiño ED, Santillán JY, Iglesias LE, Iribarren AM (2018) An enzymatic alternative for the synthesis of nucleoside 5′-monophosphates. Enzym Microb Technol 111:1–6

  • Gunne M, Urlacher VB (2012) Characterization of the alkaline laccase Ssl1 from Streptomyces sviceus with unusual properties discovered by genome mining. PLoS One 7(12):e52360

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Gunne M, Hoppner A, Hagedoorn PL, Urlacher VB (2014) Structural and redox properties of the small laccase Ssl1 from Streptomyces sviceus. FEBS J 281(18):4307–4318

    Article  CAS  PubMed  Google Scholar 

  • Guo J, Rao Z, Yang T, Man Z, Xu M, Zhang X (2014) High-level production of melanin by a novel isolate of Streptomyces kathirae. FEMS Microbiol Lett 357(1):85–91

    Article  CAS  PubMed  Google Scholar 

  • Guo J, Rao Z, Yang T, Man Z, Xu M, Zhang X, Yang ST (2015) Cloning and identification of a novel tyrosinase and its overexpression in Streptomyces kathirae SC-1 for enhancing melanin production. FEMS Microbiol Lett 362(8):fnv041

    Article  PubMed  Google Scholar 

  • Gutmann A, Schiller M, Gruber-Khadjawi M, Nidetzky B (2017) An ortho C-methylation/O-glycosylation motif on a hydroxy-coumarin scaffold, selectively installed by biocatalysis. Org Biomol Chem 15(37):7917–7924

    Article  CAS  PubMed  Google Scholar 

  • Hajer BH, Dorra ZA, Monia M, Samir B, Nushin A (2014) Probing the role of helix alpha1 in the acid-tolerance and thermal stability of the Streptomyces sp. SK glucose isomerase by site-directed mutagenesis. J Biotechnol 173:1–6

    Article  CAS  PubMed  Google Scholar 

  • H-Kittikun A, Prasertsan P, Zimmermann W, Seesuriyachan P, Chaiyaso T (2012) Sugar ester synthesis by thermostable lipase from Streptomyces thermocarboxydus ME168. Appl Biochem Biotechnol 166(8):1969–1982

    Article  CAS  PubMed  Google Scholar 

  • Horinouchi S (2007) Mining and polishing of the treasure trove in the bacterial genus streptomyces. Biosci Biotechnol Biochem 71(2):283–299

    Article  CAS  PubMed  Google Scholar 

  • Hu Y, Chou WK, Hopson R, Cane DE (2011) Genome mining in Streptomyces clavuligerus: expression and biochemical characterization of two new cryptic sesquiterpene synthases. Chem Biol 18(1):32–37

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Huber T, Schneider L, Präg A, Gerhardt S, Einsle O, Müller M (2014) Direct reductive amination of ketones: structure and activity of S-selective imine reductases from Streptomyces. ChemCatChem 6(8):2248–2252

    Article  CAS  Google Scholar 

  • Hunt M, Kikuchi T, Sanders M, Newbold C, Berriman M, Otto TD (2013) REAPR: a universal tool for genome assembly evaluation. Genome Biol 14(5):R47

    Article  PubMed  PubMed Central  Google Scholar 

  • Hussain S, Leipold F, Man H, Wells E, France SP, Mulholland KR, Grogan G, Turner NJ (2015) An (R)-imine reductase biocatalyst for the asymmetric reduction of cyclic imines. ChemCatChem 7(4):579–583

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ilangumaran G, Stratton G, Ravichandran S, Shukla PS, Potin P, Asiedu S, Prithiviraj B (2017) Microbial degradation of lobster shells to extract chitin derivatives for plant disease management. Front Microbiol 8:781

    Article  PubMed  PubMed Central  Google Scholar 

  • Ito M, Oda K (2000) An organic solvent resistant tyrosinase from Streptomyces sp. REN-21: purification and characterization. Biosci Biotechnol Biochem 64(2):261–267

    Article  CAS  PubMed  Google Scholar 

  • Jacob N, Prema P (2006) Influence of mode of fermentation on production of polygalacturonase by a novel strain of Streptomyces lydicus. Food Technol Biotechnol 44(2):263–267

    CAS  Google Scholar 

  • Jacob N, Asha Poorna C, Prema P (2008) Purification and partial characterization of polygalacturonase from Streptomyces lydicus. Bioresour Technol 99(14):6697–6701

    Article  CAS  PubMed  Google Scholar 

  • Jang HD, Chang KS (2005) Thermostable cellulases from Streptomyces sp.: scale-up production in a 50-l fermenter. Biotechnol Lett 27(4):239–242

    Article  CAS  PubMed  Google Scholar 

  • Jang H-D, Chen K-S (2003) Production and characterization of thermostable cellulases from Streptomyces transformant T3-1. World J Microbiol Biotechnol 19(3):263–268

    Article  CAS  Google Scholar 

  • Janocha S, Bernhardt R (2013) Design and characterization of an efficient CYP105A1-based whole-cell biocatalyst for the conversion of resin acid diterpenoids in permeabilized Escherichia coli. Appl Microbiol Biotechnol 97(17):7639–7649

    Article  CAS  PubMed  Google Scholar 

  • Janocha S, Zapp J, Hutter M, Kleser M, Bohlmann J, Bernhardt R (2013) Resin acid conversion with CYP105A1: an enzyme with potential for the production of pharmaceutically relevant diterpenoids. Chembiochem 14(4):467–473

    Article  CAS  PubMed  Google Scholar 

  • Jaouadi B, Abdelmalek B, Fodil D, Ferradji FZ, Rekik H, Zaraî N, Bejar S (2010) Purification and characterization of a thermostable keratinolytic serine alkaline proteinase from Streptomyces sp. strain AB1 with high stability in organic solvents. Bioresour Technol 101(21):8361–8369

    Article  CAS  PubMed  Google Scholar 

  • Jaouadi B, Rekik H, Badis A, Jaouadi NZ, Belhoul M, Hmidi M, Kourdali S, Fodil D, Bejar S (2014) Production, purification, and characterization of a highly thermostable and humic acid biodegrading peroxidase from a decolorizing Streptomyces albidoflavus strain TN644 isolated from a Tunisian off-shore oil field. Int Biodet Biodeg 90:36–44

    Article  CAS  Google Scholar 

  • Jendrossek D, Handrick R (2002) Microbial degradation of polyhydroxyalkanoates. Annu Rev Microbiol 56:403–432

    Article  CAS  PubMed  Google Scholar 

  • Jung D, Seo EY, Epstein SS, Joung Y, Han J, Parfenova VV, Belykh OI, Gladkikh AS, Ahn TS (2014) Application of a new cultivation technology, I-tip, for studying microbial diversity in freshwater sponges of Lake Baikal, Russia. FEMS Microbiol Ecol 90(2):417–423

    CAS  PubMed  Google Scholar 

  • Kar S, Ray RC (2011) Purification, characterization and application of thermostable exo-polygalacturonase fom Streptomyces erumpens MTCC 7317. J Food Biochem 35(1):133–147

    Article  CAS  Google Scholar 

  • Karthik N, Binod P, Pandey A (2015) Purification and characterisation of an acidic and antifungal chitinase produced by a Streptomyces sp. Bioresour Technol 188:195–201

    Article  CAS  PubMed  Google Scholar 

  • Kashiwagi N, Ogino C, Kondo A (2017) Production of chemicals and proteins using biomass-derived substrates from a Streptomyces host. Biores Technol 245(Pt B):1655–1663

    Article  CAS  Google Scholar 

  • Kim HJ, Kim DY, Nam JS, Bae KS, Rhee YH (2003) Characterization of an extracellular medium-chain-length poly(3-hydroxyalkanoate) depolymerase from Streptomyces sp. KJ-72. Antonie Van Leeuwenhoek 83(2):183–189

    Article  CAS  PubMed  Google Scholar 

  • Kim B-G, Jung B-R, Lee Y, Hur H-G, Lim Y, Ahn J-H (2006) Regiospecific flavonoid 7-O-methylation with Streptomyces avermitilis O-methyltransferase expressed in Escherichia coli. J Agri Food Chem 54(3):823–828

    Article  CAS  Google Scholar 

  • Kim DY, Shin DH, Jung S, Lee JS, Cho HY, Bae KS, Sung CK, Rhee YH, Son KH, Park HY (2014) Biocatalytic properties and substrate-binding ability of a modular GH10 beta-1,4-xylanase from an insect-symbiotic bacterium, Streptomyces mexicanus HY-14. J Microbiol 52(10):863–870

    Article  CAS  PubMed  Google Scholar 

  • Klementz D, Doring K, Lucas X, Telukunta KK, Erxleben A, Deubel D, Erber A, Santillana I, Thomas OS, Bechthold A, Gunther S (2016) StreptomeDB 2.0—an extended resource of natural products produced by streptomycetes. Nucleic Acids Res 44(D1):D509–D514

    Article  CAS  PubMed  Google Scholar 

  • Kohashi PY, Kumagai T, Matoba Y, Yamamoto A, Maruyama M, Sugiyama M (2004) An efficient method for the overexpression and purification of active tyrosinase from Streptomyces castaneoglobisporus. Protein Express Pur 34(2):202–207

    Article  CAS  Google Scholar 

  • Kozbial PZ, Mushegian AR (2005) Natural history of S-adenosylmethionine-binding proteins. BMC Struc Biol 5(1):19

    Article  CAS  Google Scholar 

  • Kuhad RC, Kapoor M, Rustagi R (2004) Enhanced production of an alkaline pectinase from Streptomyces sp. RCK-SC by whole-cell immobilization and solid-state cultivation. World J Microbiol Biotechnol 20(3):257–263

    Article  CAS  Google Scholar 

  • Kuipers RK, Joosten HJ, van Berkel WJ, Leferink NG, Rooijen E, Ittmann E, van Zimmeren F, Jochens H, Bornscheuer U, Vriend G, dos Santos VA, Schaap PJ (2010) 3DM: systematic analysis of heterogeneous superfamily data to discover protein functionalities. Proteins 78(9):2101–2113

    CAS  PubMed  Google Scholar 

  • Lamb DC, Waterman MR, Zhao B (2013) Streptomyces cytochromes P450: applications in drug metabolism. Expert Opin Drug Metab Toxicol 9(10):1279–1294

    Article  CAS  PubMed  Google Scholar 

  • Latarullo MB, Tavares EQ, Maldonado GP, Leite DC, Buckeridge MS (2016) Pectins, endopolygalacturonases, and bioenergy. Front Plant Sci 7:1401

    Article  PubMed  PubMed Central  Google Scholar 

  • Latham J, Brandenburger E, Shepherd SA, Menon BRK, Micklefield J (2017) Development of halogenase enzymes for use in synthesis. Chem Rev. https://doi.org/10.1021/acs.chemrev.7b00032

  • Lee N, Lee SH, Baek K, Kim BG (2015) Heterologous expression of tyrosinase (MelC2) from Streptomyces avermitilis MA4680 in E. coli and its application for ortho-hydroxylation of resveratrol to produce piceatannol. Appl Microbiol Biotechnol 99(19):7915–7924

    Article  CAS  PubMed  Google Scholar 

  • Leipold F, Hussain S, France SP, Turner NJ (2015) Imine reductases. In: Faber K, Fessner W-D, Turner NJ, Carreira EM, Decicco CP, Fürstner A, Molander GA (eds) Science of synthesis: biocatalysis in organic synthesis, Vol 2. Thieme, Stuttgart, pp 359–382

    Google Scholar 

  • Leipoldt F, Zeyhle P, Kulik A, Kalinowski J, Heide L, Kaysser L (2015) Diversity of ABBA prenyltransferases in marine Streptomyces sp. CNQ-509: promiscuous enzymes for the biosynthesis of mixed terpenoid compounds. PloS One 10(12):e0143237

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Lescic Asler I, Stefanic Z, Marsavelski A (2017) Catalytic dyad in the SGNH hydrolase superfamily: in-depth insight into structural parameters tuning the catalytic process of extracellular lipase from Streptomyces rimosus. ACS Chem Biolog 12(7):1928–1936

    Article  CAS  Google Scholar 

  • Li S, Chaulagain MR, Knauff AR, Podust LM, Montgomery J, Sherman DH (2009) Selective oxidation of carbolide C–H bonds by an engineered macrolide P450 mono-oxygenase. PNAS 106(44):18463–18468

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Liao L, Chen R, Jiang M, Tian X, Liu H, Yu Y, Fan C, Chen B (2016) Bioprospecting potential of halogenases from Arctic marine actinomycetes. BMC Microbiol 16(1):34

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Lim JH, Lee CR, Dhakshnamoorthy V, Park JS, Hong SK (2016) Molecular characterization of Streptomyces coelicolor A(3) SCO6548 as a cellulose 1,4-beta-cellobiosidase. FEMS Microbiol Lett 363(3)

  • Lin T, Kolattukudy PE (1980) Isolation and characterization of a cuticular polyester (cutin) hydrolyzing enzyme from phytopathogenic fungi. Physiological Plant Pathol 17(1):1IN15-4IN215

    Article  Google Scholar 

  • Lin X, Hopson R, Cane DE (2006) Genome mining in Streptomyces coelicolor: molecular cloning and characterization of a new sesquiterpene synthase. JACS 128(18):6022–6023

    Article  CAS  Google Scholar 

  • Liu A, Yu X-W, Sha C, Xu Y (2015) Streptomyces violaceoruber phospholipase A2: expression in Pichia pastoris, properties, and application in oil degumming. Appl Biochem Biotechnol 175:3195–3206

    Article  CAS  PubMed  Google Scholar 

  • Lucas X, Senger C, Erxleben A, Gruning BA, Doring K, Mosch J, Flemming S, Gunther S (2013) StreptomeDB: a resource for natural compounds isolated from Streptomyces species. Nucleic Acids Res 41(Database issue):D1130–D1136

    Article  CAS  PubMed  Google Scholar 

  • Mabrouk MM, Sabry SA (2001) Degradation of poly (3-hydroxybutyrate) and its copolymer poly (3-hydroxybutyrate-co-3-hydroxyvalerate) by a marine Streptomyces sp. SNG9. Microbiol Res 156(4):323–335

    Article  CAS  PubMed  Google Scholar 

  • Machczynski MC, Vijgenboom E, Samyn B, Canters GW (2004) Characterization of SLAC: a small laccase from Streptomyces coelicolor with unprecedented activity. Protein Sci 13(9):2388–2397

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Maehara T, Yagi H, Sato T, Ohnishi-Kameyama M, Fujimoto Z, Kamino K, Kitamura Y, St John F, Yaoi K, Kaneko S (2017) Characterization of a GH30 glucuronoxylan specific xylanase from Streptomyces turgidiscabies C56. Appl Environ Microbiol. https://doi.org/10.1128/aem.01850-17

  • Majumdar S, Lukk T, Solbiati JO, Bauer S, Nair SK, Cronan JE, Gerlt JA (2014) Roles of small laccases from Streptomyces in lignin degradation. Biochemistry 53(24):4047–4058

    Article  CAS  PubMed  Google Scholar 

  • Man H, Wells E, Hussain S, Leipold F, Hart S, Turkenburg JP, Turner NJ, Grogan G (2015) Structure, activity and stereoselectivity of NADPH-dependent oxidoreductases catalysing the S-selective reduction of the imine substrate 2-methylpyrroline. Chembiochem 16(7):1052–1059

    Article  CAS  PubMed  Google Scholar 

  • Mander P, Yoo HY, Kim SW, Choi YH, Cho SS, Yoo JC (2014) Transesterification of waste cooking oil by an organic solvent-tolerant alkaline lipase from Streptomyces sp. CS273. Appl Biochem Biotechnol 172(3):1377–1389

    Article  CAS  PubMed  Google Scholar 

  • Mander P, Cho SS, Choi YH, Panthi S, Choi YS, Kim HM, Yoo JC (2016) Purification and characterization of chitinase showing antifungal and biodegradation properties obtained from Streptomyces anulatus CS242. Arch Pharmaceut Res 39(7):878–886

    Article  CAS  Google Scholar 

  • Manivasagan P, Venkatesan J, Sivakumar K, Kim SK (2013) Production, characterization and antioxidant potential of protease from Streptomyces sp. MAB18 using poultry wastes. Biomed Res Int 2013:496586

    PubMed  PubMed Central  Google Scholar 

  • Margot J, Bennati-Granier C, Maillard J, Blanquez P, Barry DA, Holliger C (2013) Bacterial versus fungal laccase: potential for micropollutant degradation. AMB Express 3(1):63

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Marino SM, Fogal S, Bisaglia M, Moro S, Scartabelli G, De Gioia L, Spada A, Monzani E, Casella L, Mammi S, Bubacco L (2011) Investigation of Streptomyces antibioticus tyrosinase reactivity toward chlorophenols. Arch Biochem Biophys 505(1):67–74

    Article  CAS  PubMed  Google Scholar 

  • Markets&Markets (2015) Biocatalysis & biocatalysts market by type, application, and geography—forecast to 2019. https://www.researchandmarketscom/research/cs9p5m/biocatalysis

  • Martinez V, de Santos PG, Garcia-Hidalgo J, Hormigo D, Prieto MA, Arroyo M, de la Mata I (2015) Novel extracellular medium-chain-length polyhydroxyalkanoate depolymerase from Streptomyces exfoliatus K10 DSMZ 41693: a promising biocatalyst for the efficient degradation of natural and functionalized mcl-PHAs. Appl Microbiol Biotechnol 99(22):9605–9615

    Article  CAS  PubMed  Google Scholar 

  • Masayama A, Takahashi T, Tsukada K, Nishikawa S, Takahashi R, Adachi M, Koga K, Suzuki A, Yamane T, Nakano H, Iwasaki Y (2008) Streptomyces phospholipase D mutants with altered substrate specificity capable of phosphatidylinositol synthesis. Chembiochem 9:974–981

    Article  CAS  PubMed  Google Scholar 

  • Mate DM, Alcalde M (2016) Laccase: a multi-purpose biocatalyst at the forefront of biotechnology. Microbial Biotechnol 10(6):1457–1467

    Article  CAS  Google Scholar 

  • Matoba Y, Kumagai T, Yamamoto A, Yoshitsu H, Sugiyama M (2006) Crystallographic evidence that the dinuclear copper center of tyrosinase is flexible during catalysis. J Biol Chem 281(13):8981–8990

    Article  CAS  PubMed  Google Scholar 

  • Matsumoto Y, Mineta S, Murayama K, Sugimori D (2013) A novel phospholipase B from Streptomyces sp. NA684—purification, characterization, gene cloning, extracellular production and prediction of the catalytic residues. FEBS J 280:3780–3796

    Article  CAS  PubMed  Google Scholar 

  • Matzel P, Krautschick L, Hohne M (2017) Photometric characterization of the reductive amination scope of the imine reductases from Streptomyces tsukubaensis and Streptomyces ipomoeae. Chembiochem 18(20):2022–2027

    Article  CAS  PubMed  Google Scholar 

  • Médici R, Garaycoechea JI, Dettorre LA, Iribarren AM, Lewkowicz ES (2011) Biocatalysed halogenation of nucleobase analogues. Biotechnol Lett 33(10):1999–2003

    Article  PubMed  CAS  Google Scholar 

  • Meng K, Li J, Cao Y, Shi P, Wu B, Han X, Bai Y, Wu N, Yao B (2007) Gene cloning and heterologous expression of a serine protease from Streptomyces fradiae var.k11. Canad J Microbiol 53(2):186–195

    Article  CAS  Google Scholar 

  • Menon BRK, Latham J, Dunstan MS, Brandenburger E, Klemstein U, Leys D, Karthikeyan C, Greaney MF, Shepherd SA, Micklefield J (2016) Structure and biocatalytic scope of thermophilic flavin-dependent halogenase and flavin reductase enzymes. Org Biomol Chem 14(39):9354–9361

    Article  CAS  PubMed  Google Scholar 

  • Milbredt D, Patallo EP, van Pee KH (2016) Characterization of the aminotransferase ThdN from thienodolin biosynthesis in Streptomyces albogriseolus. Chembiochem 17(19):1859–1864

    Article  CAS  PubMed  Google Scholar 

  • Mitra P, Chakrabartty PK (2005) An extracellular protease with depilation activity from Streptomyces nogalator. JSIR 64(12):978–983

    CAS  Google Scholar 

  • Mitsukura K, Suzuki M, Tada K, Yoshida T, Nagasawa T (2010) Asymmetric synthesis of chiral cyclic amine from cyclic imine by bacterial whole-cell catalyst of enantioselective imine reductase. Org Biomol Chem 8(20):4533–4535

    Article  CAS  PubMed  Google Scholar 

  • Mitsukura K, Suzuki M, Shinoda S, Kuramoto T, Yoshida T, Nagasawa T (2011) Purification and characterization of a novel (R)-imine reductase from Streptomyces sp. GF3587. Biosci Biotechnol Biochem 75(9):1778–1782

    Article  CAS  PubMed  Google Scholar 

  • Mitsukura K, Kuramoto T, Yoshida T, Kimoto N, Yamamoto H, Nagasawa T (2013) A NADPH-dependent (S)-imine reductase (SIR) from Streptomyces sp. GF3546 for asymmetric synthesis of optically active amines: purification, characterization, gene cloning, and expression. Appl Microbiol Biotechnol 97(18):8079–8086

    Article  CAS  PubMed  Google Scholar 

  • Molina-Guijarro JM, Perez J, Munoz-Dorado J, Guillen F, Moya R, Hernandez M, Arias ME (2009) Detoxification of azo dyes by a novel pH-versatile, salt-resistant laccase from Streptomyces ipomoea. Int Microbiol 12(1):13–21

    CAS  PubMed  Google Scholar 

  • Moody SC, Loveridge EJ (2014) CYP105-diverse structures, functions and roles in an intriguing family of enzymes in Streptomyces. J Appl Microbiol 117(6):1549–1563

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Murayama K, Kano K, Matsumoto Y, Sugimori D (2013) Crystal structure of phospholipase A1 from Streptomyces albidoflavus NA297. J Struc Biol 182:192–196

    Article  CAS  Google Scholar 

  • Musengi A, Khan N, Le Roes-Hill M, Pletschke BI, Burton SG (2014) Increasing the scale of peroxidase production by Streptomyces sp. strain BSII#1. J Appl Microbiol 116(3):554–562

    Article  CAS  PubMed  Google Scholar 

  • Nakazawa Y, Sagane Y, S-i S, Uchino M, Sato H, Toeda K, Takano K (2011) Large-scale production of phospholipase D from Streptomyces racemochromogenes and its application to soybean lecithin modification. Appl Biochem Biotechnol 165:1494–1506

    Article  CAS  PubMed  Google Scholar 

  • Namwat W, Kinoshita H, Nihira T (2002) Identification by heterologous expression and gene disruption of VisA as l-lysine 2-aminotransferase essential for virginiamycin S biosynthesis in Streptomyces virginiae. J Bacteriol 184(17):4811–4818

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Narancic T, Djokic L, Kenny ST, O’Connor KE, Radulovic V, Nikodinovic-Runic J, Vasiljevic B (2012) Metabolic versatility of Gram-positive microbial isolates from contaminated river sediments. J Haz Mat 215-216:243–251

    Article  CAS  Google Scholar 

  • Narancic T, Davis R, Nikodinovic-Runic J, O’Connor KE (2015) Recent developments in biocatalysis beyond the laboratory. Biotechnol Lett 37:943–954

    Article  CAS  PubMed  Google Scholar 

  • Nguyen-Thi N, Doucet N (2016) Combining chitinase C and N-acetylhexosaminidase from Streptomyces coelicolor A3(2) provides an efficient way to synthesize N-acetylglucosamine from crystalline chitin. J Biotechnol 220:25–32

    Article  CAS  PubMed  Google Scholar 

  • Nichols D, Cahoon N, Trakhtenberg EM, Pham L, Mehta A, Belanger A, Kanigan T, Lewis K, Epstein SS (2010) Use of I-chip for high-throughput in situ cultivation of “uncultivable” microbial species. Appl Environ Microbiol 76(8):2445–2450

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Niladevi KN, Prema P (2005) Mangrove Actinomycetes as the source of ligninolytic enzymes. Actinomycetologica 19(2):40–47

    Article  CAS  Google Scholar 

  • Niladevi KN, Sheejadevi PS, Prema P (2008) Strategies for enhancing laccase yield from Streptomyces psammoticus and its role in mediator-based decolorization of azo dyes. Appl Biochem Biotechnol 151(1):9–19

    Article  CAS  PubMed  Google Scholar 

  • Pacholec M, Tao J, Walsh CT (2005) CouO and NovO: C-methyltransferases for tailoring the aminocoumarin scaffold in coumermycin and novobiocin antibiotic biosynthesis. Biochemistry 44(45):14969–14976

    Article  CAS  PubMed  Google Scholar 

  • Parajuli P, Pandey RP, Nguyen THT, Dhakal D, Sohng JK (2017) Substrate scope of O-methyltransferase from Streptomyces peucetius for biosynthesis of diverse natural products methoxides. Appl Biochem Biotechnol. https://doi.org/10.1007/s12010-017-2603-4

  • Park J, Kim D, Kim S, Kim J, Bae K, Lee C (2007) The analysis and application of a recombinant monooxygenase library as a biocatalyst for the Baeyer-Villiger reaction. J Microbiol Biotechnol 17(7):1083–1089

    CAS  PubMed  Google Scholar 

  • Parte AC (2014) LPSN—list of prokaryotic names with standing in nomenclature. Nucleic Acids Res 42(D1):D613–D616

    Article  CAS  PubMed  Google Scholar 

  • Pavkov-Keller T, Steiner K, Faber M, Tengg M, Schwab H, Gruber-Khadjawi M, Gruber K (2017) Crystal structure and catalytic mechanism of CouO, a versatile C-methyltransferase from Streptomyces rishiriensis. PLoS One 12(2):e0171056

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Pellegrini-Calace M, Maiwald T, Thornton JM (2009) PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure. PLoS Comput Biol 5(7):e1000440

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Pellis A, Cantone S, Ebert C, Gardossi L (2018) Evolving biocatalysis to meet bioeconomy challenges and opportunities. New Biotechnol 40(Pt A):154-169

  • Philp J (2018) The bioeconomy, the challenge of the century for policy makers. New Biotechnol 40(Pt A):11–19

    Article  CAS  Google Scholar 

  • Piotrowska H, Kucinska M, Murias M (2012) Biological activity of piceatannol: leaving the shadow of resveratrol. Mutation Res/Rev Mutation Res 750(1):60–82

    Article  CAS  Google Scholar 

  • Pradeep GC, Cho SS, Choi YH, Choi YS, Jee JP, Seong CN, Yoo JC (2016) An extremely alkaline mannanase from Streptomyces sp. CS428 hydrolyzes galactomannan producing series of mannooligosaccharides. World J Microbiol Biotechnol 32(5):84

    Article  CAS  Google Scholar 

  • Purushe S, Prakash D, Nawani NN, Dhakephalkar P, Kapadnis B (2012) Biocatalytic potential of an alkalophilic and thermophilic dextranase as a remedial measure for dextran removal during sugar manufacture. Bioresour Technol 115:2–7

    Article  CAS  PubMed  Google Scholar 

  • Rahman MA, Choi YH, Pradeep GC, Choi YS, Choi EJ, Cho SS, Yoo JC (2014) A novel low molecular weight endo-xylanase from Streptomyces sp. CS628 cultivated in wheat bran. Appl Biochem Biotechnol 173(6):1469–1480

    Article  CAS  PubMed  Google Scholar 

  • Ramachandra M, Crawford DL, Hertel G (1988) Characterization of an extracellular lignin peroxidase of the lignocellulolytic actinomycete Streptomyces viridosporus. Appl Environ Microbiol 54(12):3057–3063

    CAS  PubMed  PubMed Central  Google Scholar 

  • Ramesh S, Rajesh M, Mathivanan N (2009) Characterization of a thermostable alkaline protease produced by marine Streptomyces fungicidicus MML1614. Bioprocess Biosyst Eng 32(6):791–800

    Article  CAS  PubMed  Google Scholar 

  • Ramírez-Tapias YA, Rivero CW, Britos CN, Trelles JA (2015) Alkaline and thermostable polygalacturonase from Streptomyces halstedii ATCC 10897 with applications in waste waters. Biocatal Agr Biotechnol 4(2):221–228

    Google Scholar 

  • Ramirez-Tapias YA, Lapasset Laumann AS, Britos CN, Rivero CW, Trelles JA (2017) Saccharification of citrus wastes by immobilized polygalacturonase in an improved alginate matrix. Biotech 7(6):380

    Google Scholar 

  • Rathnan RK, Ambili M (2011) Cellulase enzyme production by Streptomyces sp using fruit waste as substrate. Austral J Bas Appl Sci 5(12):1114–1118

    CAS  Google Scholar 

  • Reetz MT (2002) Lipases as practical biocatalysts. Curr Opin Chem Biol 6(2):145–150

    Article  CAS  PubMed  Google Scholar 

  • Rekik H, Nadia ZJ, Bejar W, Kourdali S, Belhoul M, Hmidi M, Benkiar A, Badis A, Sallem N, Bejar S, Jaouadi B (2015) Characterization of a purified decolorizing detergent-stable peroxidase from Streptomyces griseosporeus SN9. Int J Biol Macomol 73:253–263

    Article  CAS  Google Scholar 

  • Rodriguez-Mata M, Frank A, Wells E, Leipold F, Turner NJ, Hart S, Turkenburg JP, Grogan G (2013) Structure and activity of NADPH-dependent reductase Q1EQE0 from Streptomyces kanamyceticus, which catalyses the R-selective reduction of an imine substrate. Chembiochem 14(11):1372–1379

    Article  CAS  PubMed  Google Scholar 

  • Roy S, Das I, Munjal M, Karthik L, Kumar G, Kumar S, Rao KVB (2014) Isolation and characterization of tyrosinase produced by marine actinobacteria and its application in the removal of phenol from aqueous environment. Front Biol 9(4):306–316

    Article  CAS  Google Scholar 

  • Rudolf JD, Chang CY, Ma M, Shen B (2017) Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function. Nat Prod Rep 34(9):1141–1172

    Article  CAS  PubMed  Google Scholar 

  • Sajith SPP, Sreedevi S, Benjamin S (2016) An overview on fungal cellulases with an industrial perspective. J Nutr Food Sci 6:461

    Google Scholar 

  • Sambasiva Rao KR, Tripathy NK, Mahalaxmi Y, Prakasham RS (2012) Laccase- and peroxidase-free tyrosinase production by isolated microbial strain. J Microbiol Biotechnol 22(2):207–214

    Article  CAS  PubMed  Google Scholar 

  • Sanjivkumar M, Silambarasan T, Palavesam A, Immanuel G (2017) Biosynthesis, purification and characterization of beta-1,4-xylanase from a novel mangrove associated actinobacterium Streptomyces olivaceus (MSU3) and its applications. Protein Express Purif 130:1–12

    Article  CAS  Google Scholar 

  • Santos M, Gangoiti J, Keul H, Moller M, Serra JL, Llama MJ (2013) Polyester hydrolytic and synthetic activity catalyzed by the medium-chain-length poly(3-hydroxyalkanoate) depolymerase from Streptomyces venezuelae SO1. Appl Microbiol Biotechnol 97(1):211–222

    Article  CAS  PubMed  Google Scholar 

  • Schaechter M (2009) Encyclopedia of microbiology. Academic

  • Scheller PN, Fademrecht S, Hofelzer S, Pleiss J, Leipold F, Turner NJ, Nestl BM, Hauer B (2014) Enzyme toolbox: novel enantiocomplementary imine reductases. Chembiochem 15(15):2201–2204

    Article  CAS  PubMed  Google Scholar 

  • Sehnal D, Svobodová Vařeková R, Berka K, Pravda L, Navrátilová V, Banáš P, Ionescu C-M, Otyepka M, Koča J (2013) MOLE 2.0: advanced approach for analysis of biomacromolecular channels. J Cheminformatics 5:39–39

    Article  CAS  Google Scholar 

  • Semedo LT, Gomes RC, Linhares AA, Duarte GF, Nascimento RP, Rosado AS, Margis-Pinheiro M, Margis R, Silva KR, Alviano CS, Manfio GP, Soares RM, Linhares LF, Coelho RR (2004) Streptomyces drozdowiczii sp. nov., a novel cellulolytic streptomycete from soil in Brazil. Int J Syst Evol Microbiol 54(Pt 4):1323–1328

    Article  CAS  PubMed  Google Scholar 

  • Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE (2011) Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone. Biochemistry 50(10):1739–1754

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sevillano L, Vijgenboom E, van Wezel GP, Díaz M, Santamaría RI (2016) New approaches to achieve high level enzyme production in Streptomyces lividans. Microb Cell Factories 15(1):28

    Article  CAS  Google Scholar 

  • Sharma N, Thakur N, Raj T, Savitri T, Bhalla TC (2017) Mining of microbial genomes for the novel sources of nitrilases. BioMed Res International 2017:7039245

    Google Scholar 

  • Sheldon RA, Pereira PC (2017) Biocatalysis engineering: the big picture. Chem Soc Rev 46(10):2678–2691

    Article  CAS  PubMed  Google Scholar 

  • Shepherd SA, Karthikeyan C, Latham J, Struck A-W, Thompson ML, Menon BR, Styles MQ, Levy C, Leys D, Micklefield J (2015) Extending the biocatalytic scope of regiocomplementary flavin-dependent halogenase enzymes. Chem Sci 6(6):3454–3460

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sherif M, Waung D, Korbeci B, Mavisakalyan V, Flick R, Brown G, Abou-Zaid M, Yakunin AF, Master ER (2013) Biochemical studies of the multicopper oxidase (small laccase) from Streptomyces coelicolor using bioactive phytochemicals and site-directed mutagenesis. Microbial Biotechnol 6(5):588–597

    Article  CAS  Google Scholar 

  • Shivlata L, Satyanarayana T (2017) Characteristics of raw starch-digesting α-amylase of Streptomyces badius DB-1 with transglycosylation activity and its applications. Appl Biochem Biotechnol 181(4):1–21

    Article  CAS  Google Scholar 

  • Simao FA, Waterhouse RM, Ioannidis P, Kriventseva EV, Zdobnov EM (2015) BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs. Bioinformatics 31(19):3210–3212

    Article  CAS  PubMed  Google Scholar 

  • Simkhada JR, Yoo HY, Cho SS, Choi YH, Kim SW, Park DH, Yoo JC (2012a) A novel cold-adapted lipase, LP28, from a mesophilic Streptomyces strain. Bioprocess Biosyst Eng 35(1–2):217–225

    Article  CAS  PubMed  Google Scholar 

  • Simkhada JR, Yoo HY, Choi YH, Kim SW, Yoo JC (2012b) An extremely alkaline novel xylanase from a newly isolated Streptomyces strain cultivated in corncob medium. Appl Biochem Biotechnol 168(7):2017–2027

    Article  CAS  PubMed  Google Scholar 

  • Simon C, Daniel R (2011) Metagenomic analyses: past and future trends. Appl Environ Microbiol 77(4):1153–1161

    Article  CAS  PubMed  Google Scholar 

  • Singh G, Bhalla A, Kaur P, Capalash N, Sharma P (2011) Laccase from prokaryotes: a new source for an old enzyme. Rev Environ Sci Bio/Technology 10(4):309–326

    Article  Google Scholar 

  • Skalova T, Dohnalek J, Ostergaard LH, Ostergaard PR, Kolenko P, Duskova J, Hasek J (2007) Crystallization and preliminary X-ray diffraction analysis of the small laccase from Streptomyces coelicolor. Acta Crystal Sect F, Struc Biol Cryst Comm 63(Pt 12):1077–1079

    Article  CAS  Google Scholar 

  • Sommer-Kamann C, Fries A, Mordhorst S (2017) Asymmetric C-alkylation by the S-adenosylmethionine-dependent methyltransferase SgvM. Agewandte Chem Int Ed 56(14):4033–4036

    Article  CAS  Google Scholar 

  • Song Z, Huang Z, Khan FI, Rahman S, Queen A, Ahamad S, Ali S, Kim J, Hassan MI (2017) Implications of molecular diversity of chitin and its derivatives. Appl Microbiol Biotechnol 101(9):3513–3536

    Article  CAS  Google Scholar 

  • Soror SH, Rao R, Cullum J (2009) Mining the genome sequence for novel enzyme activity: characterisation of an unusual member of the hormone-sensitive lipase family of esterases from the genome of Streptomyces coelicolor A3 (2). PEDS 22(6):333–339

    CAS  PubMed  Google Scholar 

  • Spasic J, Djokic L, Mandic M, Radivojevic J, Vasiljevic B, Nikodinovic-Runic J (2017) Biocatalytic potential of soil streptomycetes. BioTrans P-259 (Budapest, Hungary, 2017)

  • Spiker JK, Crawford DL, Thiel EC (1992) Oxidation of phenolic and non-phenolic substrates by the lignin peroxidase of Streptomyces viridosporus T7A. Appl Microbiol Biotechnol 37(4):518–523

    Article  CAS  Google Scholar 

  • Srih-Belghith K, Bejar S (1998) A thermostable glucose isomerase having a relatively low optimum pH: study of activity and molecular cloning of the corresponding gene. Biotechnol Lett 20(6):553–556

    Article  CAS  Google Scholar 

  • Stecher H, Tengg M, Ueberbacher BJ, Remler P, Schwab H, Griengl H, Gruber-Khadjawi M (2009) Biocatalytic Friedel–Crafts alkylation using non-natural cofactors. Agewandte Chem Int Ed 48(50):9546–9548

    Article  CAS  Google Scholar 

  • Sukhumsirichart W, Deesukon W, Kawakami T, Matsumoto S, Seesom W, Sakamoto T (2014) Expression and characterization of recombinant GH11 xylanase from thermotolerant Streptomyces sp. SWU10. Appl Biochem Biotechnol 172(1):436–446

    Article  CAS  PubMed  Google Scholar 

  • Suljić S, Mortzfeld FB, Gunne M, Urlacher VB, Pietruszka J (2015) Enhanced biocatalytic performance of bacterial laccase from Streptomyces sviceus: application in the Michael addition sequence towards 3-arylated 4-oxochromanes. ChemCatChem 7(8):1380–1385

    Article  CAS  Google Scholar 

  • Suzuki T, Endo K, Ito M, Tsujibo H, Miyamoto K, Inamori Y (2003) A thermostable laccase from Streptomyces lavendulae REN-7: purification, characterization, nucleotide sequence, and expression. Biosci Biotechnol Biochem 67(10):2167–2175

    Article  CAS  PubMed  Google Scholar 

  • Takahashi S, Takagi H, Toyoda A, Uramoto M, Nogawa T, Ueki M, Sakaki Y, Osada H (2010) Biochemical characterization of a novel indole prenyltransferase from Streptomyces sp. SN-593. J Bacteriol 192(11):2839–2851

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Takasuka TE, Book AJ, Lewin GR, Currie CR, Fox BG (2013) Aerobic deconstruction of cellulosic biomass by an insect-associated Streptomyces. Sci Rep 3:1030

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Tan Z, Ma H, Li Q, Pu L, Cao Y, Qu X, Zhu C, Ying H (2016) Biosynthesis of optically pure chiral alcohols by a substrate coupled and biphasic system with a short-chain dehydrogenase from Streptomyces griseus. Enzym Microb Technol 93-94:191–199

    Article  CAS  Google Scholar 

  • Thumar JT, Singh SP (2007) Secretion of an alkaline protease from a salt-tolerant and alkaliphilic, Streptomyces clavuligerus strain Mit-1. Braz J Microbiol 38:766–772

    Article  Google Scholar 

  • Tomita H, Katsuyama Y, Minami H, Ohnishi Y (2017) Identification and characterization of a bacterial cytochrome P450 monooxygenase catalyzing the 3-nitration of tyrosine in rufomycin biosynthesis. J Biol Chem 292(38):15859–15869

    Article  CAS  PubMed  Google Scholar 

  • Trincone A (2011) Marine biocatalysts: enzymatic features and applications. Mar Drugs 9(4):478–499

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Trubitsina LI, Tishchenko SV, Gabdulkhakov AG, Lisov AV, Zakharova MV, Leontievsky AA (2015) Structural and functional characterization of two-domain laccase from Streptomyces viridochromogenes. Biochimie 112:151–159

    Article  CAS  PubMed  Google Scholar 

  • Truppo MD (2017) Biocatalysis in the pharmaceutical industry: the need for speed. ACS Med Chem Lett 8(5):476–480

    Article  CAS  PubMed  Google Scholar 

  • Turner NJ, Truppo MD (2013) Biocatalysis enters a new era. Curr Opin Chem Biol 17(2):212–214

    Article  CAS  PubMed  Google Scholar 

  • Ugur A, Sarac N (2014) New lipase for biodiesel production: partial purification and characterization of LipSB 25-4. ISRN Biochem 2014:289749

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Veljkovic N, Glisic S, Prljic J, Perovic V, Botta M, Veljkovic V (2008) Discovery of new therapeutic targets by the informational spectrum method. Curr Prot Peptide Sci 9(5):493–506

    Article  CAS  Google Scholar 

  • Ventorino V, Aliberti A, Faraco V, Robertiello A, Giacobbe S, Ercolini D, Amore A, Fagnano M, Pepe O (2015) Exploring the microbiota dynamics related to vegetable biomasses degradation and study of lignocellulose-degrading bacteria for industrial biotechnological application. Sci Rep 5:8161

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ventorino V, Ionata E, Birolo L, Montella S, Marcolongo L, de Chiaro A, Espresso F, Faraco V, Pepe O (2016) Lignocellulose-adapted endo-cellulase producing Streptomyces strains for bioconversion of cellulose-based materials. Front Microbiol 7:2061

    Article  PubMed  PubMed Central  Google Scholar 

  • Ventura M, Canchaya C, Tauch A, Chandra G, Fitzgerald GF, Chater KF, van Sinderen D (2007) Genomics of Actinobacteria: tracing the evolutionary history of an ancient phylum. Microbiol Mol Biol Rev 71(3):495–548

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Vujaklija D, Schroder W, Abramic M, Zou P, Lescic I, Franke P, Pigac J (2002) A novel streptomycete lipase: cloning, sequencing and high-level expression of the Streptomyces rimosus GDS(L)-lipase gene. Arch Microbiol 178(2):124–130

    Article  CAS  PubMed  Google Scholar 

  • Wang Z, Bleakley BH, Crawford DL, Hertel G, Rafii F (1990) Cloning and expression of a lignin peroxidase gene from Streptomyces viridosporus in Streptomyces lividans. J Biotechnol 13(2):131–144

    Article  CAS  PubMed  Google Scholar 

  • Wang L, Mavisakalyan V, Tillier ER, Clark GW, Savchenko AV, Yakunin AF, Master ER (2010) Mining bacterial genomes for novel arylesterase activity. Microbial Biotechnol 3(6):677–690

    Article  CAS  Google Scholar 

  • Wang LJ, Li CX, Ni Y, Zhang J, Liu X, Xu JH (2011) Highly efficient synthesis of chiral alcohols with a novel NADH-dependent reductase from Streptomyces coelicolor. Bioresour Technol 102(14):7023–7028

    Article  CAS  PubMed  Google Scholar 

  • Wang B, Wang A, Cao Z, Zhu G (2016) Characterization of a novel highly thermostable esterase from the Gram-positive soil bacterium Streptomyces lividans TK64. Biotechnol Appl Biochem 63(3):334–343

    Article  CAS  PubMed  Google Scholar 

  • Wang X, Li D, Qu M, Durrani R, Yang B, Wang Y (2017) Immobilized MAS1 lipase showed high esterification activity in the production of triacylglycerols with n-3 polyunsaturated fatty acids. Food Chem 216:260–267

    Article  CAS  PubMed  Google Scholar 

  • Ward J, Wohlgemuth R (2010) High-yield biocatalytic amination reactions in organic synthesis. Curr Org Chem 14(17):1914–1927

    Article  CAS  Google Scholar 

  • Weber T, Blin K, Duddela S, Krug D, Kim HU, Bruccoleri R, Lee SY, Fischbach MA, Müller R, Wohlleben W, Breitling R, Takano E, Medema MH (2015) antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters. Nucleic Acids Res 43(Web Server issue):W237–W243

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wetzl D, Berrera M, Sandon N, Fishlock D, Ebeling M, Muller M, Hanlon S, Wirz B, Iding H (2015) Expanding the imine reductase toolbox by exploring the bacterial protein-sequence space. Chembiochem 16(12):1749–1756

    Article  CAS  PubMed  Google Scholar 

  • Wibberg D, Al-Dilaimi A, Busche T, Wedderhoff I, Schrempf H, Kalinowski J, Ortiz de Orue Lucana D (2016) Complete genome sequence of Streptomyces reticuli, an efficient degrader of crystalline cellulose. J Biotechnol 222:13–14

    Article  CAS  PubMed  Google Scholar 

  • Wohlleben W, Mast Y, Stegmann E, Ziemert N (2016) Antibiotic drug discovery. Microbial Biotechnol 9(5):541–548

    Article  Google Scholar 

  • Wu H, Cheng X, Zhu Y, Zeng W, Chen G, Liang Z (2017) Purification and characterization of a cellulase-free, thermostable endo-xylanase from Streptomyces griseorubens LH-3 and its use in biobleaching on eucalyptus kraft pulp. J Biosci Bioeng. https://doi.org/10.1016/j.jbiosc.2017.08.006

  • Xiao Z, Boyd J, Grosse S, Beauchemin M, Coupe E, Lau PCK (2008) Mining Xanthomonas and Streptomyces genomes for new pectinase-encoding sequences and their heterologous expression in Escherichia coli. Appl Microbiol Biotechnol 78(6):973

    Article  CAS  PubMed  Google Scholar 

  • Xu J, Yang Q (2010) Isolation and characterization of rice straw degrading Streptomyces griseorubens C-5. Biodegradation 21(1):107–116

    Article  CAS  PubMed  Google Scholar 

  • Xu Y, Wu J, Zheng K, Wu D (2016) A xylanase from Streptomyces sp. FA1: heterologous expression, characterization, and its application in Chinese steamed bread. J Ind Microbiol Biotechnol 43(5):663–670

    Article  CAS  PubMed  Google Scholar 

  • Xue Y, Li L-P, He Y-H, Guan Z (2012) Protease-catalysed direct asymmetric Mannich reaction in organic solvent. Sci Rep 2:761

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Yamamoto Y, Kurihara H, Miyashita K, Hosokawa M (2011) Synthesis of novel phospholipids that bind phenylalkanols and hydroquinone via phospholipase D-catalyzed transphosphatidylation. New Biotechnol 28:1–6

    Article  CAS  Google Scholar 

  • Yee DC, Wood TK (1997) 2,4-Dichlorophenol degradation using Streptomyces viridosporus T7A lignin peroxidase. Biotechnol Prog 13(1):53–59

    Article  CAS  PubMed  Google Scholar 

  • Yuan D, Lan D, Xin R, Yang B, Wang Y (2016) Screening and characterization of a thermostable lipase from marine Streptomyces sp. strain W007. Biotechnol Appl Biochem 63(1):41–50

    Article  CAS  PubMed  Google Scholar 

  • Zachman-Brockmeyer TR, Thoden JB, Holden HM (2017) The structure of RbmB from Streptomyces ribosidificus, an aminotransferase involved in the biosynthesis of ribostamycin. Protein Sci. https://doi.org/10.1002/pro.3221

  • Zainab MB, Madhusudhan DN, Raghavendra H, Dastager SG, Dayanand A (2014) Development of bioconjugate from Streptomyces tyrosinase and gold nanoparticles for rapid detection of phenol constituents. Indian J Exp Biol 52(11):1071–1081

    PubMed  Google Scholar 

  • Zehner S, Kotzsch A, Bister B, Süssmuth RD, Méndez C, Salas JA, van Pée K-H (2005) A regioselective tryptophan 5-halogenase is involved in pyrroindomycin biosynthesis in Streptomyces rugosporus LL-42D005. Chem Biol 12(4):445–452

    Article  CAS  PubMed  Google Scholar 

  • Zeng J, Zhan J (2011) Characterization of a tryptophan 6-halogenase from Streptomyces toxytricini. Biotechnol Lett 33(8):1607–1613

    Article  CAS  PubMed  Google Scholar 

  • Zhang R, Zhou J (2018) Enzymatic properties of beta-N-acetylglucosaminidases. Appl Microbiol Biotechnol 102(1):93–103

    Article  CAS  PubMed  Google Scholar 

  • Zhang L, Huo G, Liu W (2014) Streptomyces parvus S10A10 capable of producing neutral cellulase. Patent No CN 103937732

  • Zhang Y, Han MZ, Zhu SL, Li M, Dong X, Luo XC, Kong Z, Lu YX, Wang SY, Tong WY (2015) Studies on the function and catalytic mechanism of O-methyltransferases SviOMT02, SviOMT03 and SviOMT06 from Streptomyces virginiae IBL14. Enzym Microb Technol 73-74:72–79

    Article  CAS  Google Scholar 

  • Zhao Z, Hou S, Lan D, Wang X, Liu J, Khan FI, Wang Y (2017) Crystal structure of a lipase from Streptomyces sp. strain W007: implications for thermostability and regiospecificity. FEBS J. https://doi.org/10.1111/febs.14211

  • Zhu Y, Li X, Sun B, Song H, Li E, Song H (2012) Properties of an alkaline-tolerant, thermostable xylanase from Streptomyces chartreusis L1105, suitable for xylooligosaccharide production. J Food Sci 77(5):C506–C511

    Article  CAS  PubMed  Google Scholar 

  • Zhu T, Cheng X, Liu Y, Deng Z, You D (2013) Deciphering and engineering of the final step halogenase for improved chlortetracycline biosynthesis in industrial Streptomyces aureofaciens. Metabolic Eng 19:69–78

    Article  CAS  Google Scholar 

Download references

Funding

This work was supported by the Ministry of Education and Science, Republic of Serbia, Grant 173048. The authors also acknowledge COST Action CM1303.

Author information

Authors and Affiliations

  1. Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, P.O. Box 23, Belgrade, 11000, Serbia

    Jelena Spasic, Mina Mandic, Lidija Djokic & Jasmina Nikodinovic-Runic

Authors
  1. Jelena Spasic
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mina Mandic
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Lidija Djokic
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Jasmina Nikodinovic-Runic
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jasmina Nikodinovic-Runic.

Ethics declarations

This article does not contain any studies with human participants or animals performed by any of the authors.

Conflict of interest

The authors declare that they have no conflict of interest.

Electronic supplementary material

ESM 1

(PDF 422 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Spasic, J., Mandic, M., Djokic, L. et al. Streptomyces spp. in the biocatalysis toolbox. Appl Microbiol Biotechnol 102, 3513–3536 (2018). https://doi.org/10.1007/s00253-018-8884-x

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00253-018-8884-x

Keywords

Search

Navigation