Skip to main content
Log in

Endovascular Embolization of Visceral Artery Aneurysms with Ethylene-vinyl Alcohol (Onyx): A Case Series

  • CASE REPORT
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

We report the application of the liquid embolic agent ethylene-vinyl alcohol (Onyx; MicroTherapeutics, Irvine, CA, USA) in the management of visceral artery aneurysms. The technique and indications for using Onyx are discussed with emphasis on the management of wide-necked aneurysms and maintenance of patency of the parent vessel. None of the cases was considered suitable for stent-grafting or embolization with conventional agents. Two aneurysms of the renal artery bifurcation and one aneurysm of the inferior pancreaticoduodenal artery were treated. Following treatment there was complete exclusion of all aneurysms. There was no evidence of end-organ infarction. Follow-up with intervals up to 6 months has shown sustained aneurysm exclusion. Onyx is known to be effective in the management of intracranial aneurysms. Our experience demonstrates the efficacy and applicability of the use of Onyx in the treatment of complex visceral artery aneurysms.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1A–C
Figure 2A, B

Similar content being viewed by others

References

  1. Molyneux AJ, Cekirge S, Saatci I, et al. (2004) Cerebral Aneurysm Multicenter European Onyx (CAMEO) trial: Results of a prospective observational study in 20 European countries. AJNR Am J Neuroradiol 25:39–51

    PubMed  Google Scholar 

  2. Bubul MA, Farrow GA (1992) Renal artery aneurysms. Urology 40:124–126

    Article  Google Scholar 

  3. Henke PK, Cardneau JD, Welling TH, et al. (2001) Renal artery aneurysms: A 35 year clinical experience with 252 aneurysms in 168 patients. Ann Surg 234:454–463

    Article  PubMed  CAS  Google Scholar 

  4. Henriksson C, Bjorkerud S, Nilson AE, et al. (1985) Natural history of renal artery aneurysms elucidated by repeat angiography and pathoanatomical studies. Eur Urol 11:244–248

    PubMed  CAS  Google Scholar 

  5. Smith JN, Hinman F (1967) Intrarenal arterial aneurysms. J Urol 97:990–996

    PubMed  CAS  Google Scholar 

  6. Uher P, Nyman U, Ivancev K (1995) Aneurysms of the pancreaticoduodenal artery associated with occlusion of the coeliac artery. Abdom Imaging 20:470–473

    Article  PubMed  CAS  Google Scholar 

  7. Coll DP, Lerardi R, Kerstein MD, et al. (1998) Aneurysms of the pancreaticoduodenal arteries: A change in management. Ann Vasc Surg 12:286–291

    Article  PubMed  CAS  Google Scholar 

  8. Sutton D, Lawton G (1973) Coeliac stenosis or occlusion with aneurysm of the collateral supply. Clin Radiol 24:49–53

    Article  PubMed  CAS  Google Scholar 

  9. Kadir S, Athanosoulis CA, Yune HY, et al. (1978) Aneurysms of the pancreaticoduodenal arteries in association with coeliac axis occlusion. Cardiovasc Radiol 25:173–177

    Google Scholar 

  10. Gabelmann A, Gorich J, Merkle EM (2002) Endovascular treatment of visceral artery aneurysms. J Endovasc Ther 9:38–47

    Article  PubMed  Google Scholar 

  11. Salam TA, Lumsden AB, Martin LG, et al. (1992) Nonoperative management of visceral aneurysms and pseudoaneurysms. Am J Surg 164:215–219

    Article  PubMed  CAS  Google Scholar 

  12. Carr SC, Pearce WH, Vogelzang RL, et al. (1996) Current management of visceral artery aneurysms. Surgery 120:627–633

    Article  PubMed  CAS  Google Scholar 

  13. Kasirajan K, Greenberg RK, Clair D, et al. (2001) Endovascular management of visceral artery aneurysm. J Endovasc Ther 8:150–155

    Article  PubMed  CAS  Google Scholar 

  14. Horwitz MD, Hanbury DC, King CM (2005) Renal artery pseudoaneurysm following partial nephrectomy treated with a stent-graft. Br J Radiol 78:161–163

    Article  PubMed  CAS  Google Scholar 

  15. Bui BT, Oliva VL, Leclerc G (1995) Renal artery aneurysm: Treatment with a percutaneous placement of a stent graft. Radiology 195:181–182

    PubMed  CAS  Google Scholar 

  16. Seriki DM, Abidia A, Butterfield JS, et al. (2004) Endovascular stent graft: Treatment of pseudoaneurysm of the superior mesenteric artery. Cardiovasc Intervent Radiol 27:271–273

    Article  PubMed  Google Scholar 

  17. Gandini R, Pipitone V, Konda D, et al. (2005) Endovascular treatment of a giant superior mesenteric artery pseudoaneurysm using a Nitinol stent-graft. Cardiovasc Intervent Radiol 28:102–106

    Article  PubMed  Google Scholar 

  18. Banga N, Kessel DO, Patel JV, et al. (2005) Endovascular management of arterial conduit pseudoaneurysms following liver transplantation: A report of two cases. Transplantation 79:1763–1765

    Article  PubMed  Google Scholar 

  19. Kessel D, Wijesinghe LD, Robertson I, et al. (1999) Endovascular stent-grafts for superficial femoral artery disease: Results of 1 year follow up. J Vasc Interv Radiol 10:289–296

    Article  PubMed  CAS  Google Scholar 

  20. Parildar M, Oran I, Memis A (2003) Embolisation of visceral pseudoaneurysms with platinum coils and N-butyl cyanoacrylate. Abdom Imaging 28:36–40

    Article  PubMed  CAS  Google Scholar 

  21. Forester ND, Parry D, Kessel D, et al. (2002). Ischaemic sciatic neuropathy following embolisation of a Type II endoleak. Eur J Vasc Endovasc Surg 23:462–463

    Article  Google Scholar 

  22. Akin ED, Perkins E, Ross IB (2003) Surgical handling characteristics of an ethylene vinyl alcohol copolymer compared with N-butyl cyanoacrylate used for embolisation of vessels in an arteriovenous malformation resection model in swine. J Neurosurg 98:366–370

    Article  PubMed  CAS  Google Scholar 

  23. Jahan R, Murayama Y, Gobin YP, et al. (2001) Embolization of arteriovenous malformations with Onyx: Clinicopathological experience in 23 patients. Neurosurgery 48:984–995

    Article  PubMed  CAS  Google Scholar 

  24. Taki W, Yonekawa Y, Iwata H, et al. (1990) A new liquid material for embolization of arteriovenous malformations. AJNR Am J Neuroradiol 11:163–168

    PubMed  CAS  Google Scholar 

  25. Chaloupka JC, Huddle DC, Alderman J, et al. (1999) A re-examination of the angiotoxicity of superselective injection of DMSO in the swine rete embolization model. AJNR Am J Neuroradiol 20:401–410

    PubMed  CAS  Google Scholar 

  26. Numan F, Omeroglu A, Kara B, et al. (2004) Embolization of peripheral vascular malformations with ethylene-vinyl alcohol copolymer (Onyx). J Vasc Interv Radiol 15:939–946

    PubMed  Google Scholar 

  27. Castaneda F, Goodwin SC, Swischuk JL, et al. (2002) Treatment of pelvic arteriovenous malformations with ethylene-vinyl alcohol co-polymer (Onyx). J Vasc Radiol 13:513–516

    Google Scholar 

  28. Martin ML, Dolmatch BL, Fry PD, et al. (2001) Treatment of type II endoleaks with Onyx. J Vasc Interv Radiol 12:629–632

    PubMed  CAS  Google Scholar 

  29. Cantasdemir M, Kantarci F, Mihmanli I, et al. (2002) Embolization of profunda femoris artery branch pseudoaneurysm with ethylene-vinyl alcohol copolymer (Onyx). J Vasc Interv Radiol 7:725–728

    Google Scholar 

  30. Warakaulle DR, Aviv RI, Niemann D, et al. (2003) Embolization of spinal dural arteriovenous fistulae with Onyx. Neuroradiology 45:110–112

    PubMed  CAS  Google Scholar 

  31. Lupattelli T, Abubacker Z, Morgan R, et al. (2003) Embolization of a renal artery aneurysm using ethylene-vinyl alcohol polymer (Onyx). J Endovasc Ther 10:366–370

    Article  PubMed  Google Scholar 

  32. Saatci I, Cekirge HS, Ciceri EF, et al. (2003) CT and MR imaging findings and their implications in the follow-up of patients with intracranial aneurysms treated with endosaccular occlusion with Onyx. AJNR Am J Neuroradiol 24:567–578

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A.-M. Belli.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bratby, M., Lehmann, E., Bottomley, J. et al. Endovascular Embolization of Visceral Artery Aneurysms with Ethylene-vinyl Alcohol (Onyx): A Case Series. Cardiovasc Intervent Radiol 29, 1125–1128 (2006). https://doi.org/10.1007/s00270-005-0148-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00270-005-0148-3

Keywords

Navigation