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Dual Antiplatelet Regime Versus Acetyl-acetic Acid for Carotid Artery Stenting

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Abstract

Carotid artery stenting has been proposed as an option treatment of carotid artery stenosis. The aim of this single-institution study is to compare the dual-antiplatelet treatment and heparin combined with acetyl-acetic acid, in patients who underwent carotid artery stenting. We compared 2 groups of 50 patents each who underwent carotid artery stenting for primary atherosclerotic disease. Group A received heparin for 24 h combined with 325 mg acetyl-acetic acid and group B received 250 mg ticlopidine twice a day combined with 325 mg acetyl-acetic acid. Outcome measurements included 30-day bleeding and neurological complications and 30-day thrombosis/occlusion rates. The neurological complications were 16% in group A and 2% in group B (p < 0.05). Bleeding complications occurred in 4% in group A and 2% in group B (p > 0.05). The 30-day thrombosis/occlusion rate was 2% in group A and 0% in group B (p > 0.05). Dual antiplatelet treatment is recommended in all patients undergoing carotid artery stenting.

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Correspondence to Ilias Dalainas.

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Dalainas, I., Nano, G., Bianchi, P. et al. Dual Antiplatelet Regime Versus Acetyl-acetic Acid for Carotid Artery Stenting. Cardiovasc Intervent Radiol 29, 519–521 (2006). https://doi.org/10.1007/s00270-005-5288-y

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