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Atorvastatin-induced dermatomyositis

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Abstract

A 49-year-old man with no previous history of musculoskeletal or cutaneous problems who had a myocardial infarction (MI) was treated with atorvastatin, prasugrel, enoxaparine, and diltiazem following percutaneous coronary intervention. He was referred to our rheumatology outpatient clinic for rash and papules on the knuckles, face, and neck, as well as proximal muscle weakness. In the physical examination, a reddish rash on the face and Gottron’s papules on the knuckles were detected. The skin biopsy performed indicated interface dermatitis with hydropic degeneration of basal keratinocytes, supporting the clinical impression of dermatomyositis. He was started on prednisolone 1 mg/kg/day. After 30 days of prednisolone therapy, all symptoms disappeared.

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Acknowledgements

There was no financial support for this work and none of the authors had any financial interest or any conflict of interest with regard to this work.

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Authors and Affiliations

  1. Division of Internal Medicine, Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Mert Oztas

  2. Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Serdal Ugurlu

  3. Department of Pathology, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Ovgu Aydin

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  1. Mert Oztas
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  2. Serdal Ugurlu
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  3. Ovgu Aydin
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Correspondence to Mert Oztas.

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Oztas, M., Ugurlu, S. & Aydin, O. Atorvastatin-induced dermatomyositis. Rheumatol Int 37, 1217–1219 (2017). https://doi.org/10.1007/s00296-017-3658-9

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  • DOI: https://doi.org/10.1007/s00296-017-3658-9

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