Skip to main content
SpringerLink
Log in

Molecular identification of endocervical Chlamydia trachomatis infection among gestations at risk for preterm birth in Ecuador

  • Original Article
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Aim and method

To identify Chlamydia trachomatis (CT) endocervical infection among gestations at risk for preterm birth by means of DNA amplification.

Results

One hundred fifty eight (n = 158) gestations of Guayaquil (63.3%) and Quito (36.7%) Ecuador, at risk for preterm birth: threatened preterm labor (TPL, 60.8%) and preterm premature rupture of membranes (PPROM, 39.2%) were recruited. CT infection was presented in 8.2% of cases (TPL: 10.4% and PPROM: 4.8%). No significant difference was observed in this frequency in regard to city or diagnosis.

Conclusion

Although the causative role of CT infection for these antenatal complications cannot be completely ruled out, its presence may justify an antenatal routine screening program in order to provide appropriate therapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Claman P, Toye B, Peeling RW et al (1995) Serologic evidence of Chlamydia trachomatis infection and risk of preterm birth. CMAJ 153:259–262

    PubMed  CAS  Google Scholar 

  2. Dong ZW, Li Y, Zhang LY et al (1998) Detection of Chlamydia trachomatis intrauterine infection using polymerase chain reaction on chorionic villi. Int J Gynaecol Obstet 61:29–32

    Article  PubMed  CAS  Google Scholar 

  3. Matthews-Greer JM, McRae KL, LaHaye EB et al (2001) Validation of the Roche COBAS Amplicor system for Chlamydia trachomatis. Clin Lab Sci 14:82–84

    PubMed  CAS  Google Scholar 

  4. Paavonen J, Eggert-Kruse W (1999) Chlamydia trachomatis: impact on human reproduction. Hum Reprod Update 5:433–447

    Article  PubMed  CAS  Google Scholar 

  5. Park KH, Chaiworapongsa T, Kim YM et al (2003) Matrix metalloproteinase 3 in parturition, premature rupture of the membranes, and microbial invasion of the amniotic cavity. J Perinat Med 31:12–22

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgments

This study was funded by grant no. PIC-035-2005 awarded by FUNDACYT (Foundation for Science and Technology of Ecuador).

Author information

Authors and Affiliations

  1. Enrique C. Sotomayor Obstetrics and Gynecology Hospital, Guayaquil, Ecuador

    Marcela Medina, Luis Hidalgo & Peter Chedraui

  2. Isidro Ayora Maternity, Quito, Ecuador

    Walter Moya & Andres Calle

  3. Biomedical Center, Facultad de Ciencias Médicas, Universidad Central del Ecuador, Quito, Ecuador

    Enrique Terán

  4. Institute of Biomedicine, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, P.O. Box 09-01-4671, Guayaquil, Ecuador

    Peter Chedraui

Authors
  1. Marcela Medina
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Walter Moya
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Luis Hidalgo
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Andres Calle
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Enrique Terán
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Peter Chedraui
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Peter Chedraui.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Medina, M., Moya, W., Hidalgo, L. et al. Molecular identification of endocervical Chlamydia trachomatis infection among gestations at risk for preterm birth in Ecuador. Arch Gynecol Obstet 279, 9–10 (2009). https://doi.org/10.1007/s00404-008-0647-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00404-008-0647-y

Keywords

Search

Navigation