Abstract.
There is debate whether the terminal latency index (TLI) is a sensitive marker for polyneuropathy with anti-myelinassociated-glycoprotein antibodies (anti-MAGP). We examined 6 patients with an anti-MAGP and 6 patients with a chronic inflammatory demyelinating polyneuropathy (CIDP). The electroneurographic features studied were: distal compound motor action potential (CMAP), distal motor latency (DML), motor conduction velocity (MCV) elbow to wrist (distal MCV), MCV axilla to elbow (proximal MCV), MCV distal/proximal, terminal latency index (TLI), residual latency (RL), F-wave, and modified F ratio.We found significant differences between anti-MAGP and CIDP for DML and for RL.No significant differences were found for TLI and the other measures. The TLI values were not significant probably because our patients had a longer duration of disease,which supports the hypothesis of a distal to proximal progression of conduction slowing over time. We propose that a residual latency >4.0 and a distal motor latency >7.0 are strongly suggestive for an anti- MAGP.
Similar content being viewed by others
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Radziwill, A.J., Steck, A.J., Renaud, S. et al. Distal motor latency and residual latency as sensitive markers of anti-MAG polyneuropathy. J Neurol 250, 962– 966 (2003). https://doi.org/10.1007/s00415-003-1128-7
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s00415-003-1128-7