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Impact of the antifermentative diet during radiotherapy for prostate cancer in elderly, SÃO Paulo, Brazil

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Abstract

Objective

Assess the impact of the antifermentative diet on the dietary intake and body composition of elderly prostate cancer patients in radiotherapy.

Methods

Observational and prospective study involving 45 men aged 60 years or older, receiving radiotherapy for prostate cancer treatment. The dietary intake was assessed at four times during radiotherapy: onset (TPre), between the 11th and 16th day (T1), between the 24th and 28th day (T2), and on the last day (TLast). The body composition was assessed before and on the last day of radiotherapy, by means of the body weight and height, mid-arm circumference, triceps and subscapular skin folds, phase angle, resistance, and reactance. The data were statistically treated, considering a 5% significance level.

Results

The intake of energy, dietary fibers, and some nutrients decreased during the radiotherapy (p < 0.05). The intake of vitamins E, B1, B2, and folate, of the minerals calcium, magnesium, potassium, sodium, and phosphorus, and of the amino acid leucine dropped when the four assessment times were compared (p < 0.05). As regards the body composition, an impact was observed at the end of the radiotherapy, with lower body weight, arm circumference, subscapular cutaneous fold, phase angle and reactance (p < 0.05).

Conclusion

The antifermentative diet negatively influenced the food consumption and body composition of elderly patients submitted to radiotherapy for prostate cancer.

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Authors and Affiliations

  1. Graduate Program in the Science of Aging, Universidade São Judas Tadeu (USJT), Rua Taquari, 546 Mooca, São Paulo, CEP 03166-000 SP, Brazil

    Érica Line de Oliveira Pedron, Rita de Cássia de Aquino & Claudia Borin da Silva

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  1. Érica Line de Oliveira Pedron
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  2. Rita de Cássia de Aquino
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  3. Claudia Borin da Silva
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Correspondence to Érica Line de Oliveira Pedron.

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We hold total control over all primary data and agree to allow the journal to review the data upon request.

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All procedures performed with the participants were in accordance with the ethical standards of the institutional research committee of the São Judas Tadeu University (USJT) and the Hospital Beneficência Portuguesa de São Paulo (BPSP), under number 119636/2016.

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de Oliveira Pedron, É.L., de Cássia de Aquino, R. & Borin da Silva, C. Impact of the antifermentative diet during radiotherapy for prostate cancer in elderly, SÃO Paulo, Brazil. Support Care Cancer 28, 2969–2975 (2020). https://doi.org/10.1007/s00520-019-05187-0

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