Abstract
Upper limb function was investigated in children with ADHD using objective methods. We hypothesised that children with ADHD exhibit abnormal dexterity, force application during manipulation of a novel object, and movement rhythmicity. Two groups of age- and gender-matched children were investigated: 35 typically developing children (controls, 10.5 ± 0.4 years, 32M–3F) and 29 children (11.5 ± 0.5 years, 27M–2F) with formally diagnosed ADHD according to DSM-IV-TR criteria. Participants underwent a series of screening tests and tests of upper limb function while “off” medication. Objective quantification of upper limb function involved measurement of force during a grip and lift task, maximal finger tapping task, and maximal pinch grip. Acceleration at the index finger was also measured during rest, flexion and extension, and a postural task to quantify tremor. The Movement Assessment Battery for Children-2 (MABC-2) was also administered. Significant between-group differences were observed in movement rhythmicity, manipulation of a novel object, and performance of the MABC-2 dexterity and aiming and catching components. Children with ADHD lifted a novel object using a lower grip force (P = 0.036), and held the object with a more variable grip force (P = 0.003), than controls. Rhythmicity of finger tapping (P = 0.008) and performance on the dexterity (P = 0.007) and aiming and catching (P = 0.042) components of the MABC-2 were also significantly poorer in the ADHD group than controls. Movement speed, maximum pinch grip strength, and tremor were unaffected. The results of the study show for the first time that ADHD is associated with deficits in multiple, but not all domains of upper limb function.
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Acknowledgements
This work was funded by the Channel 7 Children’s Research Foundation (12631), National Health and Medical Research Council of Australia (GT held a Career Development Award ID 627003), and the University of South Australia.
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The ultrasound machine used in this study was funded by the Channel 7 Children’s Research Foundation.
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Hotham, E., Haberfield, M., Hillier, S. et al. Upper limb function in children with attention-deficit/hyperactivity disorder (ADHD). J Neural Transm 125, 713–726 (2018). https://doi.org/10.1007/s00702-017-1822-8
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DOI: https://doi.org/10.1007/s00702-017-1822-8