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A convenient synthesis of spiroindolo[2,1-b]quinazoline-6,2′-[1,3,4]oxadiazoles from tryptanthrin and nitrile imines

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Abstract

A convenient method for the synthesis of functionalized spiroindolo[2,1-b]quinazoline-6,2′-[1,3,4]oxadiazoles from indolo[2,1-b]quinazoline-6,12-diones and 13 hydrazonoyl chlorides in refluxing MeCN is described. These transformations are highlighted by inert atmosphere and lack of activator or metal promoters.

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Acknowledgements

We would like to thank the Research Council of Tarbiat Modares University for supporting this work.

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Authors and Affiliations

  1. Department of Chemistry, Tarbiat Modares University, PO Box 14115-175, Tehran, Iran

    Issa Yavari, Mohammad Askarian-Amiri & Zohreh Taheri

Authors
  1. Issa Yavari
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  2. Mohammad Askarian-Amiri
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  3. Zohreh Taheri
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Correspondence to Issa Yavari.

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Yavari, I., Askarian-Amiri, M. & Taheri, Z. A convenient synthesis of spiroindolo[2,1-b]quinazoline-6,2′-[1,3,4]oxadiazoles from tryptanthrin and nitrile imines. Monatsh Chem 150, 1093–1099 (2019). https://doi.org/10.1007/s00706-019-2367-3

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  • DOI: https://doi.org/10.1007/s00706-019-2367-3

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