Abstract
Periodontitis has been associated with adverse pregnancy outcomes. Results from intervention studies are few and controversial. The present study assessed the effects of non-surgical periodontal treatment in the occurrence of adverse pregnancy outcomes. Two hundred forty-six eligible women were randomly divided into two groups: periodontitis intervention (n = 122; undergoing non-surgical treatment during gestation) and periodontitis control (n = 124; not treated during gestation). Univariate analysis was performed and estimates of relative risk were reported. Data from 225 women were analyzed. No differences for preterm birth (p = 0.721), low birth weight (p = 0.198), and preterm low birth weight (p = 0.732) rates were observed. Relative risk estimates for preterm birth, low birth weight, and preterm low birth weight in the periodontitis intervention group were 0.915 (95% CI 0.561–1.493), 0.735 (95% CI 0.459–1.179), and 0.927 (0.601–1.431), respectively. Non-surgical periodontal treatment during the second semester of gestation did not reduce the risk for preterm birth, low birth weight, and preterm low birth weight.
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Acknowledgment
This study was supported by grants from the Research Fund of Pontifical Catholic University of Minas Gerais (FIP2005-24-TLE1).
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The authors declare that they have no conflict of interests.
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Oliveira, A.M.S.D., de Oliveira, P.A.D., Cota, L.O.M. et al. Periodontal therapy and risk for adverse pregnancy outcomes. Clin Oral Invest 15, 609–615 (2011). https://doi.org/10.1007/s00784-010-0424-8
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DOI: https://doi.org/10.1007/s00784-010-0424-8