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Genetics of developmental dyslexia

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An Erratum to this article was published on 28 April 2010

An Erratum to this article was published on 28 April 2010

Abstract

Developmental dyslexia is a highly heritable disorder with a prevalence of at least 5% in school-aged children. Linkage studies have identified numerous loci throughout the genome that are likely to harbour candidate dyslexia susceptibility genes. Association studies and the refinement of chromosomal translocation break points in individuals with dyslexia have resulted in the discovery of candidate genes at some of these loci. A key function of many of these genes is their involvement in neuronal migration. This complements anatomical abnormalities discovered in dyslexic brains, such as ectopias, that may be the result of irregular neuronal migration.

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  1. Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK

    Thomas S. Scerri

  2. Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Munich, Pettenkoferstr. 8a, 80336, Munich, Germany

    Gerd Schulte-Körne

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An erratum to this article can be found at http://dx.doi.org/10.1007/s00787-010-0108-6

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Scerri, T.S., Schulte-Körne, G. Genetics of developmental dyslexia. Eur Child Adolesc Psychiatry 19, 179–197 (2010). https://doi.org/10.1007/s00787-009-0081-0

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