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Influence of graphene’s chemical potential on SPR biosensor using ZnO for DNA hybridization

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Abstract

This article presents an SPR biosensor (Structure: SF10 prism-Au-ZnO-Graphene-PBS solution) to sense DNA hybridization using angular interrogation method at an operating wavelength of 633 nm. Its performance parameters, i.e., sensitivity (S), detection accuracy (DA), and figure of merit (FoM) are evaluated for different values of graphene’s chemical potential at room temperature. Sensitivity (141.9 °/RIU), DA (0.64 Degree−1) and FoM (9.14 RIU−1) are achieved for the proposed SPR biosensor at 0 eV chemical potential of graphene at the room temperature. The maximum sensitivity of 156.33°/RIU is obtained for the proposed SPR biosensor at 1.25 eV graphene’s chemical potential. The present article utilizes biocompatibility, chemical stability, and unique electrical and optical properties of both graphene and ZnO in SPR sensor for DNA hybridization.

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Acknowledgements

This work is partially supported under Project No. 34/14/10/2017-BRNS/34285 by Board of Research in Nuclear Sciences (BRNS), Department of Atomic Energy (DAE), Government of India.

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Authors and Affiliations

  1. Department of Electronics Engineering, National Institute of Technology Uttarakhand, Garhwal, Uttarakhand, 246174, India

    Sarika Pal

  2. Department of Electronics and Communication Engineering, Motilal Nehru National Institute of Technology Allahabad, Allahabad, Uttar Pradesh, 211004, India

    Yogendra Kumar Prajapati

  3. Department of Electronics Engineering, Netaji Subhas University of Technology, New Delhi, 110078, India

    J. P. Saini

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  1. Sarika Pal
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  2. Yogendra Kumar Prajapati
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  3. J. P. Saini
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Correspondence to Yogendra Kumar Prajapati.

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Pal, S., Prajapati, Y.K. & Saini, J.P. Influence of graphene’s chemical potential on SPR biosensor using ZnO for DNA hybridization. Opt Rev 27, 57–64 (2020). https://doi.org/10.1007/s10043-019-00564-w

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