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Poudres hémostatiques et hémorragies digestives

Hemostatic powders and digestive haemorrhage

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Acta Endoscopica

Résumé

Les poudres hémostatiques sont une nouvelle technique d’hémostase endoscopique développée principalement dans les hémorragies digestives hautes. Elles sont une méthode séduisante par leur facilité d’utilisation et leur innocuité. Elles s’imposent comme une alternative aux techniques d’hémostase standard. L’utilisation de l’Hemospray® est à ce jour reconnue dans les hémorragies digestives hautes non variqueuses et notamment devant des lésions difficiles d’accès par les autres techniques d’hémostase. Mais son utilisation est d’ores et déjà décrite dans les hémorragies digestives basses et celles induites par un geste endoscopique.

Abstract

Hemostatic powders are a new technique for endoscopic hemostasis developed primarily for upper gastrointestinal bleeding. They are an attractive method for their ease of use and safety. They have emerged as an alternative to standard hemostatic techniques. The use of Hemospray® is recognized in non-variceal upper gastrointestinal bleeding and especially in case of inaccessible lesions from other hemostasis techniques. But its use is already described for lower gastrointestinal bleeding and in case of bleeding related to interventional endoscopy.

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Références

  1. Nahon S, Hagège H, Latrive J, Rosa I, Nalet B, Bour B, et al. Epidemiological and prognostic factors involved in upper gastro-intestinal bleeding: results of a French prospective multicenter study. Endoscopy 2012; 44:998–1008.

    Article  CAS  PubMed  Google Scholar 

  2. Pedroto I, Dinis-Ribeiro M, Ponchon T. Is timely endoscopy the answer for cost-effective management of acute upper gastrointestinal bleeding? Endoscopy 2012;44:721–2.

    Article  CAS  PubMed  Google Scholar 

  3. Sung J, Luo D, Wu J, Ching J, Chan F, Lau J, et al. Early clinical experience of the safety and effectiveness of Hemospray in achieving hemostasis in patients with acute peptic ulcer bleeding. Endoscopy 2011;43:291–5.

    Article  CAS  PubMed  Google Scholar 

  4. Leung K, Lau J. New endoscopic hemostasis methods. Clin Endosc. 2012;45:224–9.

    Article  Google Scholar 

  5. Babiuc R, Purcarea M, Sadagurschi R, Negreanu L. Use of Hemospray in the treatment of patients with acute UGIB- short review. J Med Life 2013;6:117–9.

    PubMed Central  CAS  PubMed  Google Scholar 

  6. Giday S, Kim Y, Krishnamurty D, Ducharme R, Liang D, Shin E, et al. Long-term randomized controlled trial of a novel nanopowder hemostatic agent (TC-325) for control of severe arterial upper gastrointestinal bleeding in a porcine model. Endoscopy 2011;43:296–9.

    Article  CAS  PubMed  Google Scholar 

  7. Soulellis C, Carpentier S, Chen Y, Fallone C, Barkun A. Lower GI hemorrhage controlled with endoscopically applied TC-325 (with videos). Gastrointest Endosc 2013;77:504–7.

    Article  PubMed  Google Scholar 

  8. Huang R, Pan Y, Hui N, Guo X, Zhang L, Wang X, et al. Polysaccharide hemostatic system for hemostasis management in colorectal endoscopic mucosal resection. Dig Endosc 2014;26:63–8.

    Article  PubMed  Google Scholar 

  9. Yau A, Ou G, Galorport C, Amar J, Bressler B, Donnellan F, et al. Safety and efficacy of Hemospray® in upper gastrointestinal bleeding. Can J Gastroenterol Hepatol 2014;28:72–6.

    PubMed Central  PubMed  Google Scholar 

  10. Giday S, Van A, Van V, Ducharme R, Brandner E, Florea M, et al. Safety analysis of a hemostatic powder in a porcine model of acute severe gastric bleeding. Dig Dis Sci 2013;58:3422–8.

    Article  PubMed  Google Scholar 

  11. Smith L, Stanley A, Bergman J, Kiesslich R, Hoffman A, Tjwa E, et al. Hemospray Application in Nonvariceal Upper Gastro-intestinal Bleeding: Results of the Survey to Evaluate the Application of Hemospray in the Luminal Tract. J Clin Gastroenterol 2014;48:e89–e92.

    PubMed  Google Scholar 

  12. Chen Y, Barkun A, Soulellis C, Mayrand S, Ghali P. Use of the endoscopically applied hemostatic powder TC-325 in cancer-related upper GI hemorrhage: preliminary experience (with video). Gastrointest Endosc 2012;75:1278–81.

    Article  PubMed  Google Scholar 

  13. Leblanc S, Vienne A, Dhooge M, Coriat R, Chaussade S, Prat F. Early experience with a novel hemostatic powder used to treat upper GI bleeding related to malignancies or after therapeutic interventions (with videos). Gastrointest Endosc 2013;78:169–75.

    Article  PubMed  Google Scholar 

  14. Stanley A, Smith L, Morris A. Use of hemostatic powder (Hemospray) in the management of refractory gastric variceal hemorrhage. Endoscopy 2013;45(Suppl 2):UCTN:E86–7.

    Article  PubMed  Google Scholar 

  15. Holster I, Poley J, Kuipers E, Tjwa E. Controlling gastric variceal bleeding with endoscopically applied hemostatic powder (Hemospray™). J Hepatol 2012;57:1397–8.

    Article  PubMed  Google Scholar 

  16. Smith L, Morris A, Stanley A. The use of hemospray in portal hypertensive bleeding; a case series. J Hepatol 2014;60:457–60.

    Article  CAS  PubMed  Google Scholar 

  17. Ibrahim M, El-Mikkawy A, Mostafa I, Devière J. Endoscopic treatment of acute variceal hemorrhage by using hemostatic powder TC-325: a prospective pilot study. Gastrointest Endosc 2013;78:769–73.

    Article  PubMed  Google Scholar 

  18. Holster I, Brullet E, Kuipers E, Campo R, Fernández-Atutxa A, Tjwa E. Hemospray treatment is effective for lower gastrointestinal bleeding. Endoscopy 2014;46:75–8.

    Article  PubMed  Google Scholar 

  19. Foutch P. Angiodysplasia of the gastrointestinal tract. Am J Gastroenterol 1993;88:807–18.

    CAS  PubMed  Google Scholar 

  20. Kratt T, Lange J, Königsrainer A, Malek N, Adam P, Bösmüller H, et al. Successful Hemospray treatment for recurrent diclofenac-induced severe diffuse lower gastrointestinal bleeding avoiding the need for colectomy. Endoscopy 2014;E173–4.

    Google Scholar 

  21. Sulz M, Frei R, Meyenberger C, Bauerfeind P, Semadeni G, Gubler C. Routine use of Hemospray for gastrointestinal bleeding: prospective two-center experience in Switzerland. Endoscopy 2014;46:619–24.

    Article  PubMed  Google Scholar 

  22. Tarantino I, Barresi L, Granata A, Curcio G, Traina M. Hemospray for arterial hemorrhage following endoscopic ultrasound-guided pseudocyst drainage. Endoscopy 2014;46 Suppl 1 UCTN:E71.

    PubMed  Google Scholar 

  23. Moosavi S, Chen Y, Barkun A. TC-325 application leading to transient obstruction of a post-sphincterotomy biliary orifice. Endoscopy 2013;45(Suppl 2):UCTN:E130.

    PubMed  Google Scholar 

  24. Holster I, Kuipers E, Tjwa E. Hemospray in the treatment of upper gastrointestinal hemorrhage in patients on antithrombotic therapy. Endoscopy 2013;45:63–6.

    Article  CAS  PubMed  Google Scholar 

  25. Lanas A. Gastrointestinal bleeding associated with NSAIDs, antiplatelet therapy and anticoagulant agent. Gastroenterol Hepatol 2012;1:35–42.

    Article  Google Scholar 

  26. Jacques J, Legros R, Chaussade S, Sautereau D. Endoscopic haemostasis: An overview of procedures and clinical scenarios. Dig Liver Dis 2014;46:766–76.

    Article  PubMed  Google Scholar 

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Correspondence to M. Vincent.

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Vincent, M. Poudres hémostatiques et hémorragies digestives. Acta Endosc 45, 2–8 (2015). https://doi.org/10.1007/s10190-014-0421-x

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  • DOI: https://doi.org/10.1007/s10190-014-0421-x

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