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A micropump using amplified deformation of resilient membranes through oil hydraulics

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Abstract

Toward the development of micropumps that operate under low external air pressures, a new polydimethylsiloxane (PDMS), pneumatic micropump using amplified deformation of resilient PDMS membranes through oil hydraulics was presented in this study. The new micropump employed oil-hydraulic chambers with pre-filled mineral oil to amplify the deformation of flexible PDMS membranes; it therefore delivered a higher pumping rate and withstood a greater back pressure while requiring a significantly lower external air pressure for actuation. The optimized pumping rate and back pressure of the oil-hydraulic micropump compared favorably to previous pneumatic micropumps. Characterization of the micropump revealed that the oil hydraulics amplified the deformation of PDMS membranes by approximately threefold and improved the pumping rate and the back pressure by 77 and 21 %, respectively. With high pumping performances and the capability to be driven with only a low air pressure, this new micropump may therefore become a key component in future microfluidic devices and lab-on-a-chip systems.

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Abbreviations

MEMS:

Micro-electro-mechanical systems

LOC:

Lab-on-a-chip

PDMS:

Polydimethylsiloxane

PCR:

Polymerase chain reaction

CNC:

Computer-numerical control

PMMA:

Polymethylmethacrylate

EMV:

Electromagnetic valve

Pluronic P123:

Poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer

References

  • Arouette X, Matsumoto Y, Ninomiya T, Okayama Y, Miki N (2010) Dynamic characteristics of a hydraulic amplification mechanism for large displacement actuators systems. Sensors 10:2946–2956

    Article  Google Scholar 

  • Chen JS, Jiang JH (2012) Droplet microfluidic technology: mirodroplets formation and manipulation. Chin J Anal Chem 40:1293–1300

    Article  Google Scholar 

  • Crabtree HJ, Lauzon J, Morrissey YC, Taylor BJ, Liang T, Johnstone RW, Stickel AJ, Manage DP, Atrazhev A, Backhouse CJ, Pilarski LM (2012) Inhibition of on-chip PCR using PDMS-glass hybrid microfluidic chips. Microfluid Nanofluid 13:383–398

    Article  Google Scholar 

  • Huang CW, Lee GB (2007) A microfluidic system for automatic cell culture. J Micromech Microeng 17:1266–1274

    Article  MathSciNet  Google Scholar 

  • Huang CW, Huang SB, Lee GB (2006) Pneumatic micropumps with serially connected actuation chambers. J Micromech Microeng 16:2265–2272

    Article  Google Scholar 

  • Laser DJ, Santiago JG (2004) A review of micropumps. J Micromech Microeng 14:R35–R64

    Article  Google Scholar 

  • Lien KY, Liu CJ, Kuo PK, Lee GB (2009) Microfluidic system for detection of a-Thalassemia-1 deletion using saliva samples. Anal Chem 81:4502–4509

    Article  Google Scholar 

  • Lui C, Stelick S, Cady N, Batt C (2010) Low-power microfluidic electro-hydraulic pump (EHP). Lab Chip 10:74–79

    Article  Google Scholar 

  • Srivastava A, Sood A, Joy PS, Mandal S, Panwar R, Ravichandran S, Sarangi S, Woodcock J (2010) Principles of physics in surgery: the laws of mechanics and vectors physics for surgeons—part 2. Indian J Surg 72:355–361

    Article  Google Scholar 

  • Thorson MR, Goyal S, Schudel BR, Zukoski CF, Zhang GGZ, Gong YC, Kenis PJA (2011) A microfluidic platform for pharmaceutical salt screening. Lab Chip 11:3829–3837

    Article  Google Scholar 

  • Wang CH, Lee GB (2006) Pneumatically driven peristaltic micropumps utilizing serpentine-shape channels. J Micromech Microeng 16:341–348

    Article  Google Scholar 

  • Weng CH, Huang CC, Yeh CS, Lei HY, Lee GB (2009) Synthesis of hollow, magnetic Fe/Ga-based oxide nanospheres using a bubble templating method in a microfluidic system. Microfluid Nanofluid 7:841–848

    Article  Google Scholar 

  • Weng CH, Lien KY, Yang SY, Lee GB (2011a) A suction-type, pneumatic microfluidic device for liquid transport and mixing. Microfluid Nanofluid 10:301–310

    Article  Google Scholar 

  • Weng CH, Huang TB, Huang CC, Yeh CS, Lei HY, Lee GB (2011b) A suction-type microfluidic immunosensing chip for rapid detection of the dengue virus. Biomed Microdevices 13:585–595

    Article  Google Scholar 

  • Yang SY, Lien KY, Huang KJ, Lei HY, Lee GB (2008) Micro flow cytometry utilizing a magnetic bead-based immunoassay for rapid virus detection. Biosens Bioelectron 24:855–862

    Article  Google Scholar 

  • Ziaie B, Baldi A, Lei M, Gu Y, Siegel RA (2004) Hard and soft micromachining for BioMEMS: review of techniques and examples of applications in microfluidics and drug delivery. Adv Drug Deliv Rev 56:145–172

    Article  Google Scholar 

Download references

Acknowledgments

The authors gratefully acknowledge the financial support provided to this study by the National Science Council in Taiwan (NSC101-2218-E-007-006). Partial financial support from the “Towards a World-Class University” Project is also greatly appreciated.

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Correspondence to Gwo-Bin Lee.

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Liu, CH., Lee, GB. A micropump using amplified deformation of resilient membranes through oil hydraulics. Microfluid Nanofluid 17, 393–400 (2014). https://doi.org/10.1007/s10404-013-1316-4

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  • DOI: https://doi.org/10.1007/s10404-013-1316-4

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