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Circadian variations in immune values and serum melatonin in asthmatics

  • Microbiology and Immunology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Circadian variations in the immune status and serum melatonin were studied in asthmatics during exacerbation stage before and after treatment. Deviations from the normal (donor) immunogram values at 9.00 and 21.00 and decreased correlations between immune values and blood melatonin level were detected. The correlations of immune values between each other and with melatonin over the circadian cycle increased after treatment.

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Authors and Affiliations

  1. Institute of Clinical and Experimental Lymphology, Siberian Division of Russian Academy of medical Sciences, Novosibirsk

    G. I. Litvinenko & A. V. Shurlygina

  2. Institute of Clinical Immunology, Siberian Division of Russian Academy of medical Sciences, Novosibirsk

    V. S. Shirinskii, V. M. Nepomnyashchikh, I. V. Shirinskii, M. I. Leonova, O. L. Krugleeva, A. E. Grigoryeva & V. A. Kozlov

  3. Institute of Physiology, Siberian Division of Russian Academy of medical Sciences, Novosibirsk

    V. A. Trufakin

Authors
  1. G. I. Litvinenko
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  2. A. V. Shurlygina
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  3. V. S. Shirinskii
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  4. V. M. Nepomnyashchikh
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  5. I. V. Shirinskii
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  6. M. I. Leonova
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  7. O. L. Krugleeva
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  8. A. E. Grigoryeva
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  9. V. A. Kozlov
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  10. V. A. Trufakin
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Corresponding author

Correspondence to A. V. Shurlygina.

Additional information

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 142, No. 11, pp. 553–556, November, 2006

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Litvinenko, G.I., Shurlygina, A.V., Shirinskii, V.S. et al. Circadian variations in immune values and serum melatonin in asthmatics. Bull Exp Biol Med 142, 605–608 (2006). https://doi.org/10.1007/s10517-006-0430-7

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  • DOI: https://doi.org/10.1007/s10517-006-0430-7

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