This article reviews the criteria for assessment of hemolysis used in simulating the flow through a ventricular assist axial flow blood pump. The object of study is a model of the flow path of an axial pump consisting of a flow straightener, impeller, and diffuser. In this study, blood is considered as an incompressible Newtonian fluid with constant viscosity and density. Its flow is considered as unsteady. In the process of simulation, non-interacting control particles are introduced into the computational domain. The trajectories of the particles represent the trajectories of red blood cell movement in blood. To calculate the equivalent shear stress applied to a particle in the stream, the stress tensor is calculated at each point of the trajectory. This paper presents an equation for conversion of the stress tensor components into the equivalent shear stress. The results of the conversion are used to construct experimental hemolysis curves. Based on the obtained data, the rate of hemolysis in the flow path is compared to that in other ventricular assist devices.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Kirklin J.K. et al., J. Heart Lung Transplant, 33, No. 6, 555-564 (2014).
Selishchev S., Telyshev D., Trends Biomater. Artif. Organs, 29, No. 3 (2015).
Singh G. et al., Clin. Gastroenterol. Hepatol., 13, No. 1, 107-114(2015).
Sparrow C.T. et al., JACC: Heart Fail., 3, No. 12, 956-964 (2015).
Najjar S.S. et al., J. Heart Lung Transplant, 33, No. 1, 23-34 (2014).
Saito S. et al., J. Artif. Organs, 16, No. 1, 105-109 (2013).
Katz J.N. et al., J. Heart Lung Transplant, 34, No. 5, 701-709(2015).
Ravichandran A.K. et al., J. Heart Lung Transplant, 33, No. 1, 44-50 (2014).
Yen J.H. et al., J. Artif. Organs, 17, No. 2, 178-185 (2014).
Verteeg H.K., Malalasekera W., An Introduction to CFD (1995).
Wu J. et al., J. Fluids Eng., 134, No. 4, 041101 (2012).
Su B., Chua L.P., Wang X., Artif. Organs, 36, No. 4, 359-367(2012).
Fraser K.H. et al., Med. Eng. Phys., 33, No. 3, 263-280 (2011).
Su B. et al., Artif. Organs, 34, No. 9, 745-759 (2010).
Yang X.C. et al., Artif. Organs, 35, No. 10, 948-955 (2011).
Giersiepen M. et al., Int. J. Artif. Organs, 13, No. 5, 300-306 (1990).
Heuser G., Opitz R., Biorheology, 17, No. 1-2, 17-24 (1979).
Throckmorton A.L. et al., ASAIO J., 51, No. 5, 629-635 (2005).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Meditsinskaya Tekhnika, Vol. 50, No. 4, Jul._Aug., 2016, pp. 12_15.
Rights and permissions
About this article
Cite this article
Gouskov, A.M., Lomakin, V.O., Banin, E.P. et al. Assessment of Hemolysis in a Ventricular Assist Axial Flow Blood Pump. Biomed Eng 50, 233–236 (2016). https://doi.org/10.1007/s10527-016-9627-x
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10527-016-9627-x