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Tortuosity of coronary arteries: an indicator for impaired left ventricular relaxation?

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The International Journal of Cardiovascular Imaging Aims and scope Submit manuscript

Abstract

Objective

To investigate the relationship between coronary tortuosity and impaired left ventricular relaxation.

Methods

One hundred and four subjects who underwent coronary angiography were included in the study. Left anterior descending, left circumflex, and right coronary arteries were traced. Tortuosity was identified by the finding of ≥3 bends (defined as ≥45° change in vessel direction) along main trunk of at least one artery. Study population were divided into tortuosity (n = 54) and no tortuosity (n = 50) groups. Subjects were all submitted to pulsed-wave Doppler and two-dimensional echocardiographic examination to assess left ventricular functions.

Results

For subjects with tortuosity, early transmitral inflow (E) velocity was lower, late transmitral inflow (A) velocity was higher, E/A ratio was smaller compared with subjects without tortuosity (P < 0.001). Subjects with tortuosity had longer deceleration time of E velocity (DT) and isovolumic relaxation time (IVRT) than did subjects without tortuosity (P < 0.001). End-diastolic interventricular septal and left ventricular posterior wall thicknesses were greater in subjects with tortuosity than those without tortuosity (P = 0.01 and P = 0.005). There was an inverse correlation between total number of arteries with tortuosity and E/A ratio (r = −0.750, P < 0.001). Total number of arteries with tortuosity displayed correlations with DT (r = 0.723, P < 0.001) and IVRT (r = 0.703, P < 0.001).

Conclusions

This study depicts that coronary tortuosity is associated with impaired left ventricular relaxation.Thus, coronary tortuosity might be an indicator of impaired left ventricular relaxation.

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Abbreviations

A:

Peak late mitral inflow

BMI:

Body mass index

CI:

Confidence interval

E:

Peak early mitral inflow

DT:

Deceleration time of the E velocity

IVRT:

Isovolumic relaxation time

IVS:

Interventricular septal wall thickness at end-diastole

LAD:

Left anterior descending coronary artery

LCX:

Left circumflex coronary artery

LVEF:

Left ventricular ejection fraction

OR:

Odds ratio

PW:

Left ventricular posterior wall thickness at end-diastole

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Authors and Affiliations

  1. Department of Cardiology, Faculty of Medicine, Cumhuriyet University, Istasyon Caddesi Esen Sitesi, A-Blok No: 21, Sivas, 58030, Turkey

    Okan Turgut, Ahmet Yilmaz, Kenan Yalta, Birhan M. Yilmaz, Ali Ozyol, Omer Kendirlioglu, Filiz Karadas & Izzet Tandogan

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  1. Okan Turgut
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  2. Ahmet Yilmaz
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  3. Kenan Yalta
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  4. Birhan M. Yilmaz
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Correspondence to Okan Turgut.

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Turgut, O., Yilmaz, A., Yalta, K. et al. Tortuosity of coronary arteries: an indicator for impaired left ventricular relaxation?. Int J Cardiovasc Imaging 23, 671–677 (2007). https://doi.org/10.1007/s10554-006-9186-4

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  • DOI: https://doi.org/10.1007/s10554-006-9186-4

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