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Chemical Constituents from Aphanamixis grandifolia

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Chemistry of Natural Compounds Aims and scope

One new sterol, (3β,21α,22a)-stigmast-5-ene-3,21,22-triol (1), together with 36 compounds (2–37), were isolated from the stems of Aphanamixis grandifolia. The structure of 1 was elucidated by physical, chemical, and spectroscopic methods, including 1D and 2D NMR and HR-ESI-MS. Besides, 33 compounds (2, 4, 5, 7–10, 12–30, and 32–37) were isolated from the Aphanamixis genus for the first time, and 15 was isolated from the plant for the first time.

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Acknowledgment

The work was supported by the NCET Foundation program, NSFC (30725045 and 81102778) and partially supported by the Global Research Network for Medicinal Plants (GRNMP) and King Saud University, the Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCMCANCER Project 230232), the Key Laboratory of Drug Research for Special Environments, PLA, the Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300), and the Scientific Foundation of Shanghai China (09DZ1972200, 09DZ1975700, 09DZ1971500, 10DZ1971700).

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Authors and Affiliations

  1. School of Pharmacy, Shanghai Jiao Tong University, 200240, Shanghai, P. R. China

    Qi Zeng, Ji Ye, Jie Ren, Xiang-rong Cheng, Jiang-jiang Qin, Hui-Zi Jin & Wei-Dong Zhang

  2. School of Life Sciences and Technology, Xidian University, Xi’an, 710126, Shaanxi, P. R. China

    Qi Zeng

  3. School of Pharmacy, Second Military Medical University, 200433, Shanghai, P. R. China

    Wei-Dong Zhang

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  1. Qi Zeng
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Correspondence to Hui-Zi Jin or Wei-Dong Zhang.

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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2013, pp. 415–419.

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Zeng, Q., Ye, J., Ren, J. et al. Chemical Constituents from Aphanamixis grandifolia. Chem Nat Compd 49, 486–492 (2013). https://doi.org/10.1007/s10600-013-0644-7

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  • DOI: https://doi.org/10.1007/s10600-013-0644-7

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