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Synthesis of New Pyrazole–Methylmaleopimarate Conjugates

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Chemistry of Natural Compounds Aims and scope

Regiospecific synthesis of conjugates containing a diterpenoid fragment and a pyrazole-ring pharmacophore by 1,3-dipolar cycloaddition of diazomethane to allenoates in the presence of Et3N was demonstrated.

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Acknowledgment

The work was supported financially by a 2014 grant from the RSF Priority “Basic Research and Discovery Science by Individual Scientific Groups” (No. 14-13-01307) and RFBR Grant 13-00-14056 for information support. The spectral studies were performed using equipment of the Khimiya CCU, UfIC, RAS.

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Authors and Affiliations

  1. Ufa Institute of Chemistry, Russian Academy of Sciences, 69 Prosp. Oktyabrya, Ufa, 450054, Russia

    I. M. Sakhautdinov, A. M. Gumerov, R. N. Malikova, A. A. Fatykhov & M. S. Yunusov

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  1. I. M. Sakhautdinov
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  2. A. M. Gumerov
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  3. R. N. Malikova
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  4. A. A. Fatykhov
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  5. M. S. Yunusov
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Corresponding author

Correspondence to I. M. Sakhautdinov.

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Translated from Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2016, pp. 562–565.

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Sakhautdinov, I.M., Gumerov, A.M., Malikova, R.N. et al. Synthesis of New Pyrazole–Methylmaleopimarate Conjugates. Chem Nat Compd 52, 651–655 (2016). https://doi.org/10.1007/s10600-016-1731-3

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  • DOI: https://doi.org/10.1007/s10600-016-1731-3

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