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Stability Constants for the Equilibrium Models of Iron(III) with Several Biological Buffers in Aqueous Solutions

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Abstract

The complexation equilibria of Fe(III) with two buffer families, which are ubiquitous in biological system studies, were studied by potentiometric measurements at a constant ionic strength of I = 0.1 mol·dm−3 NaNO3 in aqueous solutions at 298.15 K. The members of TRIS family are tris(hydroxymethyl)aminomethane (TRIS), N-[tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid (TES), N-[tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid (TAPS), N-[tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid (TAPSO), and N-tris(hydroxymethyl)methyl-4-aminobutanesulfonic acid (TABS) buffers. The members of morpholine family are 4-morpholineethanesulfonic acid (MES), 4-morpholinepropanesulfonic acid (MOPS), 3-morpholino-2-hydroxypropanesulfonic acid (MOPSO), and 4-(N-morpholino) butanesulfonic acid (MOBS) buffers. The overall stability constants were determined from pH-metric data using the least-squares curve-fitting program HYPERQUAD 2008. Based on the best-fit results, the species formed at equilibrium are ML, ML2, ML2H−1, and ML3 in the systems with TRIS family buffers. The complex species ML, ML2, ML2H−1, and MLH−1 are formed in the MOPSO-containing system, while ML, ML2, and ML2H−1 are formed in the systems with MES, MOPS, and MOBS. The stabilities of the complexes fall in the order TABS > TRIS > TAPS > TAPSO > TES and MOBS > MOPS > MOPSO > MES for the TRIS family and morpholine families, respectively.

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Acknowledgments

The authors are grateful for financing provided by the National Science Council, Taiwan, through Grant No. NSC99-2811-E-011-023. MT acknowledges a postdoctoral fellowship through this grant. BSG also thanks the scholarship from National Taiwan University of Science & Technology. The authors also thank Dr. Ho-mu Lin for valuable discussions.

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  1. Department of Chemical Engineering, National Taiwan University of Science and Technology, 43 Keelung Road, Section 4, Taipei, 106-07, Taiwan

    Bhupender S. Gupta, Mohamed Taha & Ming-Jer Lee

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  1. Bhupender S. Gupta
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  2. Mohamed Taha
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Correspondence to Ming-Jer Lee.

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Gupta, B.S., Taha, M. & Lee, MJ. Stability Constants for the Equilibrium Models of Iron(III) with Several Biological Buffers in Aqueous Solutions. J Solution Chem 42, 2296–2309 (2013). https://doi.org/10.1007/s10953-013-0107-6

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