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Transition metal-free one-pot synthesis of nitrogen-containing heterocycles

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Abstract

One-pot heterocyclic synthesis is an exciting research area as it can open routes for the development of otherwise complex transformations in organic synthesis. Heterocyclic compounds show wide spectrum of applications in medicinal chemistry, chemical biology, and materials science. These heterocycles can be generated very efficiently through highly economical and viable routes using one-pot synthesis. In particular, the metal-free one-pot synthetic protocols are highly fascinating due to several advantages for the industrial production of heterocyclic frameworks. This comprehensive review is devoted to the transition metal-free one-pot synthesis of nitrogen-containing heterocycles from the period 2010–2013.

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  1. Department of Pharmacy, Banasthali University, Banasthali, 304022, Rajasthan, India

    Simpal Kumari, Sarvesh Paliwal & Rajani Chauhan

  2. Department of Chemistry, Banasthali University, Banasthali, 304022, Rajasthan, India

    Dharma Kishore, Jaya Dwivedi & Aakanksha Mishra

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Kumari, S., Kishore, D., Paliwal, S. et al. Transition metal-free one-pot synthesis of nitrogen-containing heterocycles. Mol Divers 20, 185–232 (2016). https://doi.org/10.1007/s11030-015-9596-0

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