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A study of the Immune Epitope Database for some fungi species using network topological indices

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Abstract

In the last years, the encryption of system structure information with different network topological indices has been a very active field of research. In the present study, we assembled for the first time a complex network using data obtained from the Immune Epitope Database for fungi species, and we then considered the general topology, the node degree distribution, and the local structure of this network. We also calculated eight node centrality measures for the observed network and compared it with three theoretical models. In view of the results obtained, we may expect that the present approach can become a valuable tool to explore the complexity of this database, as well as for the storage, manipulation, comparison, and retrieval of information contained therein.

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Acknowledgements

This work was supported by Grants GPC2014/058 from the Xunta de Galicia and AGL2011-30563-C03 from the Ministerio de Ciencia e Innovación, Spain. S.V.P. is supported by a postdoctoral fellowship from Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina.

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Authors and Affiliations

  1. Laboratorio de Biología Celular y Molecular, Centro de Investigación Veterinaria de Tandil (CIVETAN), CONICET, Facultad de Ciencias Veterinarias, Universidad Nacional del Centro de la Provincia de Buenos Aires (UNCPBA), Campus Universitario, 7000, Tandil, Argentina

    Severo Vázquez-Prieto & Hugo Solana

  2. Instituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Temuco, Chile

    Severo Vázquez-Prieto

  3. Laboratorio de Parasitología, Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad de Santiago de Compostela, Campus Vida, 15782, Santiago de Compostela, Spain

    Esperanza Paniagua & Florencio M. Ubeira

  4. Department of Organic Chemistry II, Faculty of Science and Technology, University of the Basque Country UPV/EHU, 48940, Leioa, Spain

    Humberto González-Díaz

  5. IKERBASQUE, Basque Foundation for Science, 48011, Bilbao, Spain

    Humberto González-Díaz

Authors
  1. Severo Vázquez-Prieto
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  2. Esperanza Paniagua
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  3. Hugo Solana
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  4. Florencio M. Ubeira
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  5. Humberto González-Díaz
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Correspondence to Severo Vázquez-Prieto.

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Vázquez-Prieto, S., Paniagua, E., Solana, H. et al. A study of the Immune Epitope Database for some fungi species using network topological indices. Mol Divers 21, 713–718 (2017). https://doi.org/10.1007/s11030-017-9749-4

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