Abstract
In present study, forensic parameters based on the population data of nineteen autosomal short tandem repeats (STRs) loci were estimated in Chinese Han populations from three riverfront areas of Yangtze Basin in Eastern China. The combined power of discrimination (CPD) were 0.9999999999999999999999883, 0.9999999999999999999999846 and 0.9999999999999999999999863, respectively. The combined power of exclusion (CPE) were 0.999999992248957, 0.999999989800400 and 0.999999989799819, respectively. Furthermore, the genetic relationships among our studied populations and 32 previously investigated populations residing in other areas of China were also analyzed based on pairwise genetic distances (FST). The multidimensional scaling (MDS) plot and phylogenetic tree indicated that our studied populations were majorly clustered with the Han populations along the Yangtze Basin and populations to the north of it. In summary, our results supported that the 19 autosomal STR loci, which were polymorphic and informative in forensic identification, could also be applied in population genetics studies.
This is a preview of subscription content, log in via an institution to check access.
References
Jobling MA, Gill P (2004) Encoded evidence: DNA in forensic analysis. Nat Rev Genet 5(10):739–751
Kayser M, de Knijff P (2011) Improving human forensics through advances in genetics, genomics and molecular biology. Nat Rev Genet 12(3):179–192
Walsh PS, Metzger DA, Higuchi R (2013) Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. Biotechniques 54(3):134–139
Excoffier L, Lischer HE (2010) Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 10(3):564–567
Zhao F, Wu X, Cai G, Xu C (2003) The application of Modified-Powerstates software in forensic biostatistics (in Chinese). Chin J Forensic Med 18(5):297–298
Hansen J (2000) Using SPSS for windows and Macintosh: analyzing and understanding data. Am Stat 59(1):113
Kumar S, Stecher G, Tamura K (2016) MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets. Mol Biol Evol 33(7):1870–1874
Yuan J, Wang X, Shen C, Liu W, Yan J, Wang H et al (2014) Genetic profile characterization and population study of 21 autosomal STR in Chinese Kazak ethnic minority group. Electrophoresis 35(4):503–510
Sokal RR, Michener CD (1958) A statistical method for evaluating systematic relationships. Univ Kansas Sci Bull 38:1409–1437
Xu S, Yin X, Li S, Jin W, Lou H, Yang L et al (2009) Genomic dissection of population substructure of Han Chinese and its implication in association studies. Am J Hum Genet 85(6):762–774
He G, Wang Z, Wang M, Hou Y (2017) Genetic diversity and phylogenetic differentiation of southwestern Chinese Han: a comprehensive and comparative analysis on 21 non-CODIS STRs. Sci Rep 7(1):13730
Zou X, Li Y, Li P, Nie Q, Wang T, Hu Y et al (2017) Genetic polymorphisms for 19 autosomal STR loci of Chongqing Han ethnicity and phylogenetic structure exploration among 28 Chinese populations. Int J Legal Med 131(6):1539–1542
Wang M, Wang Z, Zhang Y, He G, Liu J, Hou Y (2017) Forensic characteristics and phylogenetic analysis of two Han populations from the southern coastal regions of China using 27 Y-STR loci. Forensic Sci. Int Genet 31:e17–e23
Nothnagel M, Fan G, Guo F, He Y, Hou Y, Hu S et al (2017) Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y–STR haplotypes. Hum Genet 136(5):485–497
Zhang S, Bian Y, Li L, Sun K, Wang Z, Zhao Q et al (2015) Population genetic study of 34 X-chromosome markers in 5 main ethnic groups of China. Sci Rep 5:17711
Acknowledgements
This study was supported by grants from the National Key R&D Program of China (Grant No. 2016YFC0800703), Standard Program of Shanghai Municipality (Grant Nos. 16DZ0501600, 18DZ1200300), Public Interest Research Grant Programs of National Research Institutes (Grant No. GY2017D-2) and the National Natural Science Foundation (Grant Nos. 81625013, 81772028). The funders had no role in study design, data analysis, publishing decisions, or manuscript preparation.
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Electronic supplementary material
Below is the link to the electronic supplementary material.
11033_2019_4633_MOESM2_ESM.tif
Fig. S1. A heatmap illustrating the allele distribution of our studied populations and other 22 previously reported Han populations. The color gradually turns from white to red as the allelic frequency increases. Hierarchical clustering based on the Euclidean distances was also performed on each shared locus—Supplementary material 2 (TIF 28658 KB)
11033_2019_4633_MOESM3_ESM.tif
Fig. S2. A map showing the geographical distribution of our studied populations and another 32 previously published Chinese populations applied in this comparison, including 22 Han populations and 10 ethnic minorities. The three studied populations were underlined—Supplementary material 3 (TIF 10113 KB)
Rights and permissions
About this article
Cite this article
Tao, R., Wang, S., Jin, M. et al. Forensic characteristics and phylogenetic structure of Eastern Chinese Han populations residing along the Yangtze Basin revealed by 19 autosomal STR loci. Mol Biol Rep 46, 2541–2546 (2019). https://doi.org/10.1007/s11033-019-04633-w
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11033-019-04633-w