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Recent Advances in Antiviral Benzimidazole Derivatives: A Mini Review

  • MOLECULAR-BIOLOGICAL PROBLEMS OF DRUG DESIGN AND MECHANISM OF DRUG ACTION
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Pharmaceutical Chemistry Journal Aims and scope

Benzimidazole ring system is well known for its potential for various biological activities. Recent research works have indicated the excellent antiviral potential of various derivatives of this heterocycle. Depending upon the nature of substitution and side chain functionalities, benzimidazole derivatives exhibit anti-HCV, anti-HBV, anti-HIV, anti-HSV, anti-Coxsackie virus, anti-rotavirus, anti-mosquito larvae, anti-PRSV, anti-adenovirus, anti-tobacco mosaic, and anti-Sunn-hemp rosette viruses, etc. In this article, the recent literature available on antiviral benzimidazole derivatives is summarized. The article could be useful in designing new antiviral agents based on this ring system.

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Acknowledgements

The authors gratefully appreciate the Higher Education Commission of Pakistan and the Government College University (Faisalabad, Pakistan) for kindly providing free access to scientific journals.

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Authors and Affiliations

  1. Department of Chemistry, Government College University, Faisalabad, 38000, Pakistan

    Afshan Kanwal, Matloob Ahmad & Syed Ali Raza Naqvi

  2. Department of Chemistry, Government College Women University, Faisalabad, 38000, Pakistan

    Sana Aslam

  3. Department of Applied Chemistry, Government College University, Faisalabad, 38000, Pakistan

    Muhammad Jawwad Saif

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  1. Afshan Kanwal
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  2. Matloob Ahmad
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  4. Syed Ali Raza Naqvi
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Correspondence to Matloob Ahmad.

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Kanwal, A., Ahmad, M., Aslam, S. et al. Recent Advances in Antiviral Benzimidazole Derivatives: A Mini Review. Pharm Chem J 53, 179–187 (2019). https://doi.org/10.1007/s11094-019-01976-3

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  • DOI: https://doi.org/10.1007/s11094-019-01976-3

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