Skip to main content
Log in

Sorption Properties of Sunflower Husk Melanins

  • MEDICINAL PLANTS
  • Published:
Pharmaceutical Chemistry Journal Aims and scope

The sorption properties of sunflower husk melanins were studied according to pharmacopoeial monograph GPM.1.2.3.0021.15 using marker compounds methylene blue, methyl orange, gelatin, and iodine. The sorption capacities of the studied samples were found to be 190.9 ± 4.2 mg/g for methylene blue; 302.1 ± 1.8, methyl orange; 114.7 ± 2.8, gelatin; and 38.4 ± 2.4%, I2 . The sorption capacities of the samples were greater than those of the sorbents Polifepan and Polysorb and comparable with that of activated charcoal for medium-molecular-mass toxicants. The melanins showed high affinity for anionic substances. The protein-binding capacities of the melanins were inferior only to that of Polysorb and significantly greater than those of Polifepan and activated charcoal. The sorption capacity for I2 matched that of Polifepan and was >1.5 times less than that of activated charcoal. The results showed that enterosorbents based on melanins could be developed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. V. G. Nikolaev, S. V. Mikhalovskii, and N. M. Gurina, Efferentnaya Ter., 11(4), 3 – 17 (2005).

    Google Scholar 

  2. S. A. Kuznetsova, M. L. Shchipko, B. N. Kuznetsov, et al., Khim. Rastit. Syr’ya, No. 2, 25 – 29 (2004).

  3. E. V. Veprikova, M. L. Shchipko, S. A. Kuznetsova, et al., Khim. Rastit. Syr’ya, No. 1, 65 – 70 (2005).

  4. E. S. Kokh, A. S. Gavrikov, A. A. Tumashov, et al., Nauchn. Vedom. BelGU Ser.: Med. Farm., 201(4), 160 – 166 (2015).

    Google Scholar 

  5. M. G. Ismailov, Kh. M. Makhkamov, and P. L. Ismailov, Khim.-farm. Zh., 34(12), 38 – 40 (2000).

    Google Scholar 

  6. O. Yu. Kuznetsova, Vestn. Kazan. Tekhnol. Univ., 23(16), 136 – 138 (2013).

    Google Scholar 

  7. N. V. Sushinskaya, T. A. Kukulyanskaya, N. V. Gavrilenko, et al., Usp. Med. Mikol., 3(3), 192 – 195 (2004).

    Google Scholar 

  8. N. V. Ikonnikova, I. A. Goncharova, and N. M. Rovbel’, Usp. Med. Mikol., 5, 187 – 190 (2005).

    Google Scholar 

  9. D. A. Novikov, Tr. BGU Ser.: Fiziol., Biokhim. Mol. Osnovy Funktsion. Biosistem, 1, 105 – 114 (2006).

    Google Scholar 

  10. E. A. Prutenskaya, A. S. Vasil’ev, E. Yu. Lebedeva, et al., Simvol Nauki, 11, No. 3, 11 – 13 (2016).

    Google Scholar 

  11. V. A. Baraboi, Usp. Sovrem. Biol., 12, 1 – 12 (2001).

    Google Scholar 

  12. N. V. Gracheva, V. F. Zheltobryukhov, and V. F. Kablov, in: Proceedings of the IInd All-Russian Scientific-Practical Internet-Conference with International Participation [in Russian], Petrozavodsk, 2016, pp. 19 – 22.

  13. G. Britton, The Biochemistry of Natural Pigments, Cambridge Univ. Press, New York, 1983, 366 pp. [Russian translation, Mir Moscow, 1986, pp. 92 – 99, 259 – 279].

  14. N. V. Gracheva, Vestn. Kazan. Tekhnol. Univ., 19(15), 154 – 157 (2016).

    CAS  Google Scholar 

  15. S. P. Lyakh, Microbial Melaninogenesis and Its Function [in Russian], Nauka, Moscow, 1981, pp. 22 – 270.

    Google Scholar 

  16. L. A. Kazitsina and N. B. Kupletskaya, Applications of UV, IR and NMR Spectroscopy in Organic Chemistry [in Russian], Vysshaya Shkola, Moscow, 1971, pp. 23 – 60, 235 – 257.

  17. V. S. Chuchalin and N. V. Kelus, Razrab. Regist. Lek. Sredstv, 12(12), 86 – 91 (2015).

    Google Scholar 

  18. E. V. Veprikova, S. A. Kuznetsova, G. P. Skvortsova, et al., SibFU J. Chem., 1(3), 286 – 292 (2008).

    Google Scholar 

  19. V. I. Reshetnikov, Khim.-farm. Zh., 37(5), 28 – 32 (2003).

    Google Scholar 

  20. D. N. Olennikov, Author’s Abstract of a Doctoral Dissertation in Pharmaceutical Sciences, Ulan-Ude, 2012.

  21. N. V. Kelus, V. V. Sheikin, A. E. Gundareva, et al., Byull. Sib. Med., No. 1, 121 – 125 (2011).

  22. V. M. Mukhin, P. V. Uchanov, and N. I. Sotnikova, Sorbtsionnye Khromatogr. Protsessy, 13(1), 83 – 90 (2013).

    CAS  Google Scholar 

  23. E. P. Gernikova, A. I. Luttseva, T. N. Bokovikova, et al., Vedom. NTsESMP, No. 4, 48 – 50 (2013).

  24. V. N. Panfilova and T. E. Taranushenko, Pediatr. Farmakol., 9(6), 34 – 39 (2012).

    Article  Google Scholar 

  25. V. A. Solov’ev and A. M. Kutnevich, Higher Fungi and Their Physiologically Active Compounds [in Russian], Nauka, Leningr. Otd., Leningrad, 1973, pp. 35 – 39.

    Google Scholar 

  26. D. A. Markelov, O. V. Nitsak, and I. I. Gerashchenko, Khim.- farm. Zh., 42(7), 30 – 33 (2008).

    Google Scholar 

  27. A. A. Chuiko (ed.), Medicinal Chemistry and Clinical Application of Silicon Dioxide [in Russian], Naukova Dumka, Kiev, 2003, pp. 12 – 18, 131 – 144.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to N. V. Gracheva.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 53, No. 4, pp. 34 – 38, April, 2019.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gracheva, N.V., Zheltobryukhov, V.F. Sorption Properties of Sunflower Husk Melanins. Pharm Chem J 53, 337–341 (2019). https://doi.org/10.1007/s11094-019-02002-2

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11094-019-02002-2

Keywords

Navigation