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Synthesis of polycationic lipids based on cholesterol and spermine

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Abstract

The synthesis of cholesterol-based cationic lipids in which the hydrophobic steroidal fragment is linked to a spermine residue as the hydrophilic domain by ester or carbamate linkage is described.

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Authors and Affiliations

  1. M. V. Lomonosov Moscow State Academy of Fine Chemical Tehnology, 86 Prospect Vernadskogo, 119571, Moscow, Russian Federation

    I. A. Petukhov, M. A. Maslov, N. G. Morozova & G. A. Serebrennikova

Authors
  1. I. A. Petukhov
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  2. M. A. Maslov
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  3. N. G. Morozova
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  4. G. A. Serebrennikova
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Corresponding author

Correspondence to M. A. Maslov.

Additional information

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 254–261, January, 2010.

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Petukhov, I.A., Maslov, M.A., Morozova, N.G. et al. Synthesis of polycationic lipids based on cholesterol and spermine. Russ Chem Bull 59, 260–268 (2010). https://doi.org/10.1007/s11172-010-0071-x

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  • DOI: https://doi.org/10.1007/s11172-010-0071-x

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