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Ferrocene modification of organic compounds for medicinal applications

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Abstract

The results of the authors on the synthesis of ferrocene-containing organic compounds obtained in 1998–2013 are summarized. The review is focused on the ferrocene modifications of purine and pyrimidine bases, thiopyrimidines, natural and synthetic amino acids, azoles (including polyfluoroazoles and mercaptoazoles) and ferrocenyl quinoline synthesis. The special attention is given to the scale synthesis of compounds for biological trials.

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Authors and Affiliations

  1. A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation

    L. V. Snegur, A. A. Simenel & A. N. Rodionov

  2. K. A. Timiryazev Russian State Agrarian University, Build. 49, 10 ul. Timiryazevskaya, 127550, Moscow, Russian Federation

    V. I. Boev

Authors
  1. L. V. Snegur
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  2. A. A. Simenel
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  3. A. N. Rodionov
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  4. V. I. Boev
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Corresponding author

Correspondence to L. V. Snegur.

Additional information

Dedicated to the Memory of Professor Yu. S. Nekrasov, a prominent Scientist and Person.

Based on the materials of the Cluster of Conferences on Organic Chemistry “OrgKhim 2013” (July 17–21, 2013, Saint Petersburg, Repino).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 0026–0036, January, 2014.

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Snegur, L.V., Simenel, A.A., Rodionov, A.N. et al. Ferrocene modification of organic compounds for medicinal applications. Russ Chem Bull 63, 26–36 (2014). https://doi.org/10.1007/s11172-014-0390-4

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  • DOI: https://doi.org/10.1007/s11172-014-0390-4

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