Abstract
The effect of carbon nanotubes (CNTs) on the morphology and properties of alginate hydrogel was studied. The addition of CNTs leads to a change in the structural characteristics of the hydrogel, which is expressed in a decrease in the pore size and gaining a more uniformity by the internal structure. To study the encapsulating properties of the designed compositions, a set of dyes was used that are traditionally applied for testing the drug release rate. It was found that the CNTs do not affect the efficiency of inclusion and the release rate of the anionic and neutral dyes. The change in the kinetics of cationic dye release is caused by the reinforcing effect of the CNTs on the alginate hydrogel and a change in its morphological characteristics.
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This work was carried out in the framework of the state task of the Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,” (L. R. Bogdanova, L. Ya. Zakharova, and Yu. F. Zuev, general analysis of results) and financially supported in part by the Russian Foundation for Basic Research (Project No. 19-38-90085, A. O. Makarova, SEM analysis) and the Cooperative Project of the Russian Foundation for Basic Research and the Government of the Tatarstan Republic (Project No. 18-415-160011, L. R. Bogdanova and Yu. F. Zuev, kinetic experiments).
Based on the materials of the International Markovnikov Congress on Organic Chemistry (June 21–28, 2019, Moscow—Kazan, Russia).
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 3, pp. 0590–0595, March, 2020.
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Bogdanova, L.R., Makarova, A.O., Zueva, O.S. et al. Encapsulation of diagnostic dyes in the polysaccharide matrix modified by carbon nanotubes. Russ Chem Bull 69, 590–595 (2020). https://doi.org/10.1007/s11172-020-2803-x
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DOI: https://doi.org/10.1007/s11172-020-2803-x