Abstract
The following chromium(III) complexes with serine (Ser) and aspartic acid (Asp) were obtained and characterized in solution: [Cr(ox)2(Aa)]2− (where Aa = Ser or Asp), [Cr(AspH−1)2]− and [Cr(ox)(Ser)2]−. In acidic solutions, [Cr(ox)2(Aa)]2− undergoes acid-catalysed aquation to cis-[Cr(ox)2(H2O)2]− and the appropriate amino acid. [Cr(ox)(Ser)2]− undergoes consecutive acid-catalysed Ser liberation to give [Cr(ox)(H2O)4]+, and the [Cr(Asp)2]− ion is converted into [Cr(Asp)(H2O)4]2+. Kinetics of these reactions were studied under isolation conditions. The determined rate expressions for all the reactions are of the form: k obs = a + b[H+]. Reaction mechanisms are proposed, and the meaning of the determined parameters has been established. Evidence for the formation of an intermediate with O-monodentate amino acid is given. The effect of the R-substituent at the α-carbon atom of the amino acid on the complex reactivity is discussed.
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Mertz W (1993) J Nutr 123:626
Evans GW, Pouchnik DJ (1993) J Inorg Biochem 49:177
Vincent JB (2001) Polyhedron 20:1
Slesinski RS, Clarke JJ, San RHC, Gudi R (2005) Mutation Res 585:86
Stallings D, Vincent JB (2006) CurrTopics Nutraceutical Res 4:89
Nielsen FH (2007) Summary: the clinical and nutritional importance of chromium—still debated after 50 years of research. In: Vincent JB (ed) The nutritional biochemistry of chromium(III). Elsevier, Amsterdam, pp 265–276
Vincent JB (2010) Dalton Trans 39:3787
Levina A, Codd R, Dillon CT, Lay PA (2003) Chromium in biology: toxicology and nutritional Aspects. In: Karlin KD (ed) Progress in inorganic chemistry, vol 51, Wiley, Hoboken, NJ, pp 145–250
Kita E, Marai H, Muzioł T, Lenart K (2011) Transit Met Chem 36:35
Kita E, Lisiak R (2011) Transit Met Chem 36:855
Metzler DE (2001) Biochemistry, 2nd edn, Academic Press, Harcourt, p 53
Sasada Y, Takenaka A, Furuya T (1983) Bull Chem Soc Jpn 56:1745
Krylova LF, Matveeva LM, Romanenko GV (2006) Zh Struct Khim 47:670
Zobi F, Spingler B, Alberto R (2005) Dalton Trans 2859–2865
Versiane O, Felcman J, de Miranda JL, Howie RA, Skakle JMS (2005) Acta Crystallogr Sect E: Struct Rep Online 61:m2517
Bravo J, Cataviela C, Chaves JE, Navarro R, Urriolabeitia EP (2003) Inorg Chem 42:1006
Barfod R, Bendahl L, Hammershoi A, Jensen DK, Sargeson AM, Willis AC (1999) J Chem Soc Dalton Trans 449–457
Atria AM, Valenzuela J, Vega A, Garcia AM (1997) J Chem Cryst 27:429
Madafiglio K, Manning TM, Murdoch CM, Tulip WR, Cooper MK, Hambley TW, Freeman HC (1990) Acta Crystallogr Sect C Crystal Struct Commun 46:554
Vaidhyanathan R, Bradshaw D, Rebilly J-N, Barrio JP, Gould JA, Berry NG, Rosseinsky (2006) Angew Chem Int Ed 45: 6495
Battaglia LP, Corradi AB, Antolini L, Marcotrigiano G, Menabue L, Pallacani GC (1982) J Am Soc 104:2407
Marek J, Pavelcik F (2003) Acta Crystallogr Sect C Cryst Struct Commun 59:m178
MacDiarmig AG, ed-in-chief (1977) Inorg Synthesis, vol 17, Mc Graw-Hill Inc, New York, p 149
Bailey JL (1962) Techniques in protein chemistry. Elsevier, Amsterdam, p 73
Kallen TW, Hamm RL (1977) Inorg Chem 16:1147
Berjea D, Chaudhuri SD (1970) J Inorg Nucl Chem 32:2985
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Marai, H., Kita, E., Wojciechowska, J. et al. Kinetic studies on H+-catalysed aquation of some chromium(III)-oxalato-amino acid complexes. Transition Met Chem 37, 215–223 (2012). https://doi.org/10.1007/s11243-012-9579-2
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DOI: https://doi.org/10.1007/s11243-012-9579-2