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Fusarium solani, Tax-3, a new endophytic taxol-producing fungus from Taxus chinensis

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Abstract

An endophytic fungus, Tax-3, was isolated from barks of Taxus chinensis grown in the Qinba mountains, China. The strain was classified into Fusarium solani based on the morphological characteristics and the molecular phylogenetics inferred from the nuclear ribosomal DNA ITS sequences with the sequence similarity values of 100%. High performance liquid chromatography (HPLC) assay showed the F. solani, Tax-3, produced taxol with a higher yield of 163.35 μg/L in the reformative potato dextrose liquid medium (d), revealing its potential applications for taxol production.

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Acknowledgments

We would like to thank Tajalli Keshavarz and anonymous reviewers for their critical reviews of the manuscript and acknowledge Dr. Bin Liu for critical reading of the manuscript. The work was supported jointly by projects from Shaanxi Educational Committee (08JZ21, 08JK244, 08JK248).

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Authors and Affiliations

  1. School of Biological Sciences and Engineering, Shaanxi University of Technology, Hanzhong, Shaanxi, 723001, People’s Republic of China

    Bai Wan Deng, Kai Hui Liu, Wen Qiang Chen, Xiao Wei Ding & Xiu Chao Xie

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  1. Bai Wan Deng
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  2. Kai Hui Liu
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  3. Wen Qiang Chen
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  4. Xiao Wei Ding
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  5. Xiu Chao Xie
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Corresponding authors

Correspondence to Bai Wan Deng or Kai Hui Liu.

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Bai Wan Deng and Kai Hui Liu contributed equally to this work.

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Deng, B.W., Liu, K.H., Chen, W.Q. et al. Fusarium solani, Tax-3, a new endophytic taxol-producing fungus from Taxus chinensis . World J Microbiol Biotechnol 25, 139–143 (2009). https://doi.org/10.1007/s11274-008-9876-2

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  • DOI: https://doi.org/10.1007/s11274-008-9876-2

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