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Nanoinformatics and biomolecular nanomodeling: a novel move en route for effective cancer treatment

  • Nanotechnology, Nanopollution, Nanotoxicology and Nanomedicine (NNNN)
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Abstract

Empowering role of nanoinformatics in design and elucidation of nanoparticles for effective cancer treatment has made this field a fascinating area for researchers, inspiring them to enhance up the quality and efficacy of existing anticancer medicines. Theoretical and computational modeling is being seen as a forefront solution for problems related to surface chemistry, optimized geometry, or other properties in nanoparticle designing and drug delivery. The current review aims to acquaint with the insight story of the incubation of in silico tools and techniques in nanotechnology to develop better anticancer nanomedicines. The review also recapitulates the assets and liabilities of this field and present an outline of existing inventiveness and endeavors of nanoinformatics. We propose how nanoinformatics could hasten up the advancements in anticancer nanomedicines through use of computational tools, nanoparticles repositories & various modeling and simulation methods.

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Authors and Affiliations

  1. Department of Bioengineering, Faculty of Engineering, Integral University, Lucknow, UP, 226026, India

    Neha Sharma & Salman Akhtar

  2. Advanced Center of Bioengineering and Bioinformatics, Integral Information and Research Centre, Integral University, Lucknow, UP, 226026, India

    Neha Sharma, Mala Sharma & Salman Akhtar

  3. Department of Biosciences, Integral University, Lucknow, UP, 226026, India

    Mala Sharma

  4. Department of Health Informatics, College of Public Health and Health Informatics, Qassim University, King Abdulaziz Rd, Al Bukayriyah, 52741, Al Qassim, Saudi Arabia

    Qazi M Sajid Jamal

  5. King Fahad Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia

    Mohammad A. Kamal

  6. Enzymoics, 7, Peterlee Place, Hebersham, NSW, 2770, Australia

    Mohammad A. Kamal

  7. Novel Global Community Educational Foundation, Peterlee Place, Hebersham, NSW, 2770, Australia

    Mohammad A. Kamal & Salman Akhtar

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  1. Neha Sharma
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  3. Qazi M Sajid Jamal
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Sharma, N., Sharma, M., Sajid Jamal, Q.M. et al. Nanoinformatics and biomolecular nanomodeling: a novel move en route for effective cancer treatment. Environ Sci Pollut Res 27, 19127–19141 (2020). https://doi.org/10.1007/s11356-019-05152-8

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