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A new triterpene from the green walnut husks of Juglans mandshurica Maxim

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Abstract

A new triterpene named klodorol B (1), together with six known compounds, were isolated from the green walnut husks of Juglans mandshurica Maxim. Their structures were determined using spectroscopic methods on the basis of 1D and 2D NMR, and high-resolution electrospray ionization mass spectrometry. The isolated compounds were evaluated for their cytotoxic activities on human gastric carcinoma (BGC-823), human liver cancer (HepG-2) and human lung cancer (A549) cell lines.

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Acknowledgements

This work was supported by the National Science Foundation of China (No. 81202890), Natural Science Foundation of Heilongjiang Province of China (No. LH2019H048), China Postdoctoral Science Foundation funded project (Nos. 2013M530164 and 2014T70374), Heilongjiang Postdoctoral Fund (Nos. LBH-Z13195 and LBH-Q16207), and Harbin City Youth Science and Technology Innovation Talents (No. 2013RFQXJ052).

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Authors and Affiliations

  1. College of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin, 150040, China

    Yuan-Yuan Zhou, Hong-Juan Song, Shuang Guo, Ying Wang, Hui-Rui Gao, Yan-Ping Sun, Yan Liu, Bing-You Yang & Hai-Xue Kuang

  2. Academic Research Department, Heilongjiang University of Chinese Medicine, Harbin, 150040, China

    Xiao-Juan Zhang

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  1. Yuan-Yuan Zhou
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Correspondence to Bing-You Yang or Hai-Xue Kuang.

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Zhou, YY., Song, HJ., Guo, S. et al. A new triterpene from the green walnut husks of Juglans mandshurica Maxim. J Nat Med 73, 800–804 (2019). https://doi.org/10.1007/s11418-019-01309-4

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