Skip to main content
SpringerLink
Log in

Visualization Strategies for Major White Matter Tracts for Intraoperative Use

  • Original articles
  • Published:
International Journal of Computer Assisted Radiology and Surgery Aims and scope Submit manuscript

Abstract

Streamline representation of major fiber tract systems along with high-resolution anatomical data provides a reliable orientation for the neurosurgeon. For intraoperative visualization of these data either on navigation screens near the surgical field or directly in the surgical field applying heads-up displays of operating microscopes, wrapping of all streamlines of interest to render an individual object representing the whole fiber bundle is the most suitable representation. Integration of fiber tract data into a neuronavigation setup allows removal of tumors adjacent to eloquent brain areas with low morbidity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Basser PJ, Mattiello J, LeBihan D (1994) MR diffusion tensor spectroscopy and imaging. Biophys J 66:259–267

    PubMed  CAS  Google Scholar 

  2. Basser PJ, Pajevic S, Pierpaoli C, Duda J, Aldroubi A (2000) In vivo fiber tractography using DT-MRI data. Magn Reson Med 44:625–632

    Article  PubMed  CAS  Google Scholar 

  3. Berman JI, Berger MS, Mukherjee P, Henry RG (2004) Diffusion-tensor imaging-guided tracking of fibers of the pyramidal tract combined with intraoperative cortical stimulation mapping in patients with gliomas. J Neurosurg 101:66–72

    PubMed  Google Scholar 

  4. Clark CA, Barrick TR, Murphy MM, Bell BA (2003) White matter fiber tracking in patients with space-occupying lesions of the brain: a new technique for neurosurgical planning?. Neuroimage 20:1601–1608

    Article  PubMed  Google Scholar 

  5. Coenen VA, Krings T, Mayfrank L, Polin RS, Reinges MH, Thron A, Gilsbach JM (2001) Three-dimensional visualization of the pyramidal tract in a neuronavigation system during brain tumor surgery: first experiences and technical note. Neurosurgery 49:86–93

    Article  PubMed  CAS  Google Scholar 

  6. Cruz Junior LC, Sorensen AG (2005) Diffusion tensor magnetic resonance imaging of brain tumors. Neurosurg Clin N Am 16:115–134

    Article  PubMed  Google Scholar 

  7. Enders F, Iserhardt-Bauer S, Hastreiter P, Nimsky C, Ertl T (2005) Hardware-accelerated glyph based visualization of major white matter tracts for analysis of brain tumors. In: Galloway RJ, K (eds) Medical imaging 2005: visualization, image-guided procedures, and display, Proceedings of SPIE, vol 5744, Bellingham, WA, pp 504–511

  8. Fillard P, Gilmore J, Lin W, Gerig G (2003) Quantitative analysis of white matter fiber properties along geodesic paths. In: Ellis RE, Peters TM (eds) medical image computing and computer-assisted intervention – MICCAI 2003. Springer, Berlin Heidelberg New York, pp 16–23

    Google Scholar 

  9. Ganslandt O, Fahlbusch R, Nimsky C, Kober H, Möller M, Steinmeier R, Romstöck J, Vieth J (1999) Functional neuronavigation with magnetoencephalography: outcome in 50 patients with lesions around the motor cortex. J Neurosurg 91:73–79

    PubMed  CAS  Google Scholar 

  10. Hendler T, Pianka P, Sigal M, Kafri M, Ben-Bashat D, S, Graif M, Fried I, Assaf Y (2003) Delineating gray and white matter involvement in brain lesions: three-dimensional alignment of functional magnetic resonance and diffusion-tensor imaging. J Neurosurg 99:1018–1027

    PubMed  Google Scholar 

  11. Holodny AI, Schwartz TH, Ollenschleger M, Liu WC, Schulder M (2001) Tumor involvement of the corticospinal tract: diffusion magnetic resonance tractography with intraoperative correlation. J Neurosurg 95:1082

    PubMed  CAS  Google Scholar 

  12. Jobard B, Lefer W (1997) Creating evenlyspaced streamlines of arbitrary density. Visualization in scientific computing 97. In: Proceedings of the Eurographics workshop in Boulogne-sur-Mer, France. Springer, Berlin Heidelberg New York, pp 43–56

  13. Kamada K, Todo T, Masutani Y, Aoki S, Ino K, Takano T, Kirino T, Kawahara N, Morita A (2005) Combined use of tractography-integrated functional neuronavigation and direct fiber stimulation. J Neurosurg 102:664–672

    Article  PubMed  Google Scholar 

  14. Kindlmann G (2004) Superquadric tensor glyphs. In: Proceedings of Eurographics - IEEE TCVG symposium on visualization, pp 147–154

  15. Kober H, Nimsky C, Möller M, Hastreiter P, Fahlbusch R, Ganslandt O (2001) Correlation of sensorimotor activation with functional magnetic resonance imaging and magnetoencephalography in presurgical functional imaging: a spatial analysis. Neuroimage 14:1214–1228

    Article  PubMed  CAS  Google Scholar 

  16. Lazar M, Weinstein DM, Tsuruda JS, Hasan KM, Arfanakis K, Meyerand ME, Badie B, Rowley HA, Haughton V, Field A, Alexander AL (2003) White matter tractography using diffusion tensor deflection. Hum Brain Mapp 18:306–321

    Article  PubMed  Google Scholar 

  17. Le Bihan D, Van Zijl P (2002) From the diffusion coefficient to the diffusion tensor. NMR Biomed 15:431–434

    Article  PubMed  Google Scholar 

  18. Lu S, Ahn D, Johnson G, Cha S (2003) Peritumoral diffusion tensor imaging of high-grade gliomas and metastatic brain tumors. AJNR Am J Neuroradiol 24:937–941

    PubMed  Google Scholar 

  19. Merhof D, Hastreiter P, Nimsky C, Fahlbusch R, Greiner G (2005) Directional volume growing for the extraction of white matter tracts from diffusion tensor data. In: Galloway RJ, Cleary K (eds) Medical imaging 2005: visualization, image-guided procedures, and display, Proceedings of SPIE, vol 5744, Bellingham, WA, USA, pp 165–172

  20. Mori S, Van Zijl PC (2002) Fiber tracking: principles and strategies – a technical review. NMR Biomed 15:468–480

    Article  PubMed  Google Scholar 

  21. Nimsky C, Ganslandt O, Hastreiter P, Wang R, Benner T, AG, Fahlbusch R (2005) Preoperative and intraoperative diffusion tensor imaging-based fiber tracking in glioma surgery. Neurosurgery 56:130–138

    PubMed  Google Scholar 

  22. Nimsky C, Ganslandt O, Kober H, Möller M, Ulmer S, Tomandl B, Fahlbusch R (1999) Integration of functional magnetic resonance imaging supported by magnetoencephalography in functional neuronavigation. Neurosurgery 44:1249–1256

    Article  PubMed  Google Scholar 

  23. Nimsky C, Grummich P, Sorensen AG, Fahlbusch R, Ganslandt O (2005) Visualization of the pyramidal tract in glioma surgery by integrating diffusion tensor imaging in functional neuronavigation. Zentralbl Neurochir 66:133–141

    Article  PubMed  CAS  Google Scholar 

  24. Pierpaoli C, Jezzard P, Basser PJ, Barnett A, Di Chiro G (1996) Diffusion tensor MR imaging of the human brain. Radiology 201:637–648

    PubMed  CAS  Google Scholar 

  25. Price S, Burnet N, Donovan T, Green H, Pena A, Antoun N, Pickard J, Carpenter T, Gillard J (2003) Diffusion tensor imaging of brain tumours at 3T: a potential tool for assessing white matter tract invasion?. Clin Radiol 58:455–462

    Article  PubMed  CAS  Google Scholar 

  26. Stieltjes B, Kaufmann WE, van Zijl PC, Fredericksen K, Pearlson GD, Solaiyappan M, Mori S (2001) Diffusion tensor imaging and axonal tracking in the human brainstem. Neuroimage 14:723–735

    Article  PubMed  CAS  Google Scholar 

  27. Vilanova A, Berenschot G, Pul van C (2004) DTI Visualization with streamsurfaces and evenly-spaced volume seeding. In: Proceedings of Joint EG/IEEE TCVG visual Symposium pp 173–182

  28. Weinstein DM, Kindlman GL, Lundberg EC (1999) Tensorlines: advection-diffusion based propagation through diffusion tensor fields. In: Ebert DS, Gross MH, Hamann B (eds) IEEE visualization 1999. IEEE Computer Society and ACM, San Francisco, pp 249–253

    Google Scholar 

  29. Westin CF, Maier SE, Mamata H, Nabavi A, Jolesz FA, Kikinis R (2002) Processing and visualization for diffusion tensor MRI. Med Image Anal 6:93–108

    Article  PubMed  Google Scholar 

  30. Yamada K, Kizu O, Mori S, Ito H, Nakamura H, Yuen S, Kubota T, Tanaka O, Akada W, Sasajima H, Mineura K, Nishimura T (2003) Brain fiber tracking with clinically feasible diffusion-tensor MR imaging: initial experience. Radiology 227:295–301

    Article  PubMed  Google Scholar 

  31. Zhukov L, Barr A (2002) Oriented tensor reconstruction: tracing neural pathways from diffusion tensor MRI. Visualization. In: Proceedings of the conference on visualization 02. IEEE Computer Society, Washington, DC, USA, pp 387–394

  32. Zöckler M, Stalling D, Hege H-C (1996) Interactive visualization of 3D-vector fields using illuminated stream lines. IEEE visualization. In: Proceedings of the 7th conference on visualization 96. IEEE Computer Society Press, Los Alamitos, CA, USA, pp 107–113

Download references

Author information

Authors and Affiliations

  1. Department of Neurosurgery, University Erlangen–Nuremberg, NErlanger, Germany

    Christopher Nimsky, Oliver Ganslandt & Michael Buchfelder

  2. Neurocenter, University Erlangen–Nuremberg, NErlanger, Germany

    Christopher Nimsky, Oliver Ganslandt, Frank Enders, Dorit Merhof, Thilo Hammen & Michael Buchfelder

  3. Department of Neurology, University Erlangen–Nuremberg, NErlanger, Germany

    Thilo Hammen

Authors
  1. Christopher Nimsky
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Oliver Ganslandt
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Frank Enders
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Dorit Merhof
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Thilo Hammen
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Michael Buchfelder
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Christopher Nimsky.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nimsky, C., Ganslandt, O., Enders, F. et al. Visualization Strategies for Major White Matter Tracts for Intraoperative Use. Int J CARS 1, 13–22 (2006). https://doi.org/10.1007/s11548-006-0003-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11548-006-0003-2

Keywords

Search

Navigation