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Clinical use of cardiac PET/MRI: current state-of-the-art and potential future applications

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Abstract

Combined PET/MRI is a novel imaging method integrating the advances of functional and morphological MR imaging with PET applications that include assessment of myocardial viability, perfusion, metabolism of inflammatory tissue and tumors, as well as amyloid deposition imaging. As such, PET/MRI is a promising tool to detect and characterize ischemic and non-ischemic cardiomyopathies. To date, the greatest benefit may be expected for diagnostic evaluation of systemic diseases and cardiac masses that remain unclear in cardiac MRI, as well as for clinical and scientific studies in the setting of ischemic cardiomyopathies. Diagnosis and therapeutic monitoring of cardiac sarcoidosis has the potential of a possible ‘killer-application’ for combined cardiac PET/MRI. In this article, we review the current evidence and discuss current and potential future applications of cardiac PET/MRI.

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    Authors and Affiliations

    1. Department of Radiology, Diagnostic and Interventional Radiology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany

      Patrick Krumm, Stefanie Mangold, Sergios Gatidis, Konstantin Nikolaou & Fabian Bamberg

    2. Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

      Felix Nensa

    3. Department of Radiology, Nuclear Medicine and Clinical Molecular Imaging, University of Tübingen, Tübingen, Germany

      Christian la Fougère

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    1. Patrick Krumm
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    2. Stefanie Mangold
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    Correspondence to Patrick Krumm.

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    Fabian Bamberg and Christian la Fougère share senior authorship.

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    Krumm, P., Mangold, S., Gatidis, S. et al. Clinical use of cardiac PET/MRI: current state-of-the-art and potential future applications. Jpn J Radiol 36, 313–323 (2018). https://doi.org/10.1007/s11604-018-0727-2

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