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CRISPR/Cas-mediated genome editing in sorghum — recent progress, challenges and prospects

  • Special Issue on Genome Editing
  • Published:
In Vitro Cellular & Developmental Biology - Plant Aims and scope Submit manuscript

Abstract

Sorghum is a versatile crop with great potential as a sustainable food, feed, and bioenergy source. To mitigate the severely negative impact of climate change and population growth on food and energy security, further elevation of the crops stress tolerance is urgently needed. Genome editing technologies such as CRISPR/Cas have great potential to accelerate functional genomics and crop improvement by supporting targeted modification of almost any crop gene sequence. We describe the recent progress in genome editing of sorghum. In addition, we review remaining challenges and prospects of emerging gene editing technologies for rapid precision breeding of this crop.

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Funding

This review was partially funded by the DOE Center for Advanced Bioenergy and Bioproducts Innovation (U.S. Department of Energy, Office of Science, Office of Biological and Environmental Research) under award number DE-SC0018420.

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Author notes

  1. Mehmet Cengiz Baloglu

    Present address: Department of Genetics and Bioengineering, Kastamonu University, Kastamonu, Turkey

Authors and Affiliations

  1. Agronomy Department, University of Florida, IFAS, 3085 McCarty Hall B, Gainesville, FL, 32603, USA

    Aalap Parikh, Eleanor J. Brant, Mehmet Cengiz Baloglu & Fredy Altpeter

  2. DOE Center for Advanced Bioenergy and Bioproducts Innovation, Gainesville, FL, USA

    Aalap Parikh, Eleanor J. Brant & Fredy Altpeter

Authors
  1. Aalap Parikh
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  2. Eleanor J. Brant
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  3. Mehmet Cengiz Baloglu
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  4. Fredy Altpeter
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Contributions

AP and EB contributed equally to this manuscript and should be considered joint first authors. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Fredy Altpeter.

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Parikh, A., Brant, E.J., Baloglu, M.C. et al. CRISPR/Cas-mediated genome editing in sorghum — recent progress, challenges and prospects. In Vitro Cell.Dev.Biol.-Plant 57, 720–730 (2021). https://doi.org/10.1007/s11627-021-10215-y

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  • DOI: https://doi.org/10.1007/s11627-021-10215-y

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