Abstract
Magnesium (Mg) alloys have been recently introduced as a biodegradable implant for orthopedic applications. However, their fast corrosion, low bioactivity, and mechanical integrity have limited their clinical applications. The main aim of this research was to improve such properties of the AZ91 Mg alloy through surface modifications. For this purpose, nanostructured fluoridated hydroxyapatite (FHA) was coated on AZ91 Mg alloy by micro-arc oxidation and electrophoretic deposition method. The coated alloy was characterized through scanning electron microscopy, transmission electron microscopy, X-ray diffraction, in vitro corrosion tests, mechanical tests, and cytocompatibility evaluation. The results confirmed the improvement of the corrosion resistance, in vitro bioactivity, mechanical integrity, and the cytocompatibility of the coated Mg alloy. Therefore, the nanostructured FHA coating can offer a promising way to improve the properties of the Mg alloy for orthopedic applications.
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Acknowledgments
The authors are thankful for the contributions of Isfahan University of Technology, Torabinejad Dental Research Center, Oklahoma Center for Advancement of Science and Technology (Grant no. AR131-054 8161), AFOSR (Grant no. FA9550-10-1-0010) and the National Science Foundation (NSF, Grant no. 0933763).
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Manuscript submitted May 17, 2014.
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Razavi, M., Fathi, M., Savabi, O. et al. In Vitro Analysis of Electrophoretic Deposited Fluoridated Hydroxyapatite Coating on Micro-arc Oxidized AZ91 Magnesium Alloy for Biomaterials Applications. Metall Mater Trans A 46, 1394–1404 (2015). https://doi.org/10.1007/s11661-014-2694-2
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DOI: https://doi.org/10.1007/s11661-014-2694-2