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The Impact of Bariatric Surgery on Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis

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Abstract

Bariatric surgery has been proven to be a successful management strategy for morbid obesity, but limited studies exist on its effect on polycystic ovary syndrome (PCOS). A comprehensive search of electronic databases was completed. Meta-analysis was performed on PCOS, hirsutism, and menstrual irregularity outcomes following bariatric surgery. Thirteen primary studies involving a total of 2130 female patients were identified. The incidence of PCOS preoperatively was 45.6 %, which significantly decreased to 6.8 % (P < 0.001) and 7.1 % (P < 0.0002) at 12-month follow-up and study endpoint, respectively. The incidences of preoperative menstrual irregularity and hirsutism both significantly decreased at 12-month and at study end follow-up. Bariatric surgery effectively attenuates PCOS and its clinical symptomatology including hirsutism and menstrual irregularity in severely obese women.

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Authors and Affiliations

  1. Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada

    Daniel Skubleny

  2. Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada

    Noah J. Switzer, Richdeep S. Gill, Mark Dykstra, Christopher de Gara, Daniel W. Birch & Shahzeer Karmali

  3. Centre for the Advancement of Minimally Invasive Surgery (CAMIS), Royal Alexandra Hospital, Edmonton, Canada

    Richdeep S. Gill, Xinzhe Shi, Christopher de Gara, Daniel W. Birch & Shahzeer Karmali

  4. Department of Obstetrics and Gynecology, University of Alberta, Edmonton, Canada

    Margaret A. Sagle

  5. 2D, Walter C Mackenzie Health Sciences Centre, University of Alberta, 840-112 Street, T6G 2B7, Edmonton, Canada

    Noah J. Switzer

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  1. Daniel Skubleny
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  2. Noah J. Switzer
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Correspondence to Noah J. Switzer.

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Skubleny, D., Switzer, N.J., Gill, R.S. et al. The Impact of Bariatric Surgery on Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis. OBES SURG 26, 169–176 (2016). https://doi.org/10.1007/s11695-015-1902-5

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  • DOI: https://doi.org/10.1007/s11695-015-1902-5

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