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The Use of Biomarkers in the Patient with Heart Failure

  • Congestive Heart Failure (J Lindenfeld, Section Editor)
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Abstract

Heart failure is a major burden to the health care system in terms of not only cost, but also morbidity and mortality. Appropriate use of biomarkers is critically important to allow rapid identification and optimal risk stratification and management of patients with both acute and chronic heart failure. This review will discuss the biomarkers that have the most diagnostic, prognostic, and therapeutic value in patients with heart failure. We will discuss established biomarkers such as natriuretic peptides as well as emerging biomarkers reflective of myocyte stress, myocyte injury, extracellular matrix injury, and both neurohormonal and cardio-renal physiology.

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Acknowledgments

Research support for this paper was provided by Alere, Abbott, Nanosphere, Brahms-thermofisher, and Novartis.

Conflict of Interest

Punam Chowdhury declares that he has no conflict of interest.

Devin Kehl declares that he has no conflict of interest.

Rajiv Choudhary declares that he has no conflict of interest.

Alan Maisel has been a consultant for Alere, BG Medicine, and Critical Diagnostics; has received grant support from BG Medicine and Alere; has received payment for development of educational presentations including service on speakers’ bureaus for BG Medicine; and has received travel/accommodations expenses covered or reimbursed from multiple companies.

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Authors and Affiliations

  1. San Diego Veteran’s Affairs Medical Center, San Diego, CA, USA

    Punam Chowdhury, Devin Kehl & Alan Maisel

  2. University of California San Diego, San Diego, CA, USA

    Punam Chowdhury, Devin Kehl & Alan Maisel

  3. Capitol Health Regional Medical Center, Trenton, NJ, USA

    Rajiv Choudhary

  4. VAMC Emergency Department, 3350 La Jolla Village Drive, San Diego, CA, 92161, USA

    Punam Chowdhury

Authors
  1. Punam Chowdhury
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  2. Devin Kehl
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  3. Rajiv Choudhary
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  4. Alan Maisel
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Corresponding author

Correspondence to Punam Chowdhury.

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This article is part of the Topical Collection on Congestive Heart Failure

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Chowdhury, P., Kehl, D., Choudhary, R. et al. The Use of Biomarkers in the Patient with Heart Failure. Curr Cardiol Rep 15, 372 (2013). https://doi.org/10.1007/s11886-013-0372-4

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  • DOI: https://doi.org/10.1007/s11886-013-0372-4

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