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Macrophage migration inhibitory factor and its genetic association with arthritis: A work in progress

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References

  1. Bucala R, Lolis E: Macrophage migration inhibitory factor: A critical component of autoimmune inflammatory diseases. Drug News Perspect 2005, 18:417–426.

    Article  PubMed  CAS  Google Scholar 

  2. Radstake TR, Sweep FC, Welsing P, et al.: Correlation of rheumatoid arthritis severity with the genetic functional variants and circulating levels of macrophage migration inhibitory factor. Arthritis Rheum 2005, 52:3020–3029.

    Article  PubMed  CAS  Google Scholar 

  3. De Benedetti F, Meazza C, Vivarelli M, et al.: Functional and prognostic relevance of the −173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 2003, 48:1398–1407.

    Article  PubMed  Google Scholar 

  4. Leech M, Metz C, Bucala R, Morand EF: Regulation of macrophage migration inhibitory factor by endogenous glucocorticoids in rat adjuvant-induced arthritis. Arthritis Rheum 2000, 43:827–833.

    Article  PubMed  CAS  Google Scholar 

  5. Donn RP, Shelley E, Ollier WE, Thomson W: A novel 5′-flanking region polymorphism of macrophage migration inhibitory factor is associated with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 2001, 44:1782–1785.

    Article  PubMed  CAS  Google Scholar 

  6. Donn R, Alourfi Z, De Benedetti F, et al.: Mutation screening of the macrophage migration inhibitory factor gene: positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic arthritis. Arthritis Rheum 2002, 46:2402–2409.

    Article  PubMed  CAS  Google Scholar 

  7. Baugh JA, Chitnis S, Donnelly SC, et al.: A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis. Genes Immun 2002, 3:170–176.

    Article  PubMed  CAS  Google Scholar 

  8. Barton A, Lamb R, Symmons D, et al.: Macrophage migration inhibitory factor (MIF) gene polymorphism is associated with susceptibility to but not severity of inflammatory polyarthritis. Genes Immun 2003, 4:487–491.

    Article  PubMed  CAS  Google Scholar 

  9. Amoli MM, Donn RP, Thomson W, et al.: Macrophage migration inhibitory factor gene polymorphism is associated with sarcoidosis in biopsy proven erythema nodosum. J Rheumatol 2002, 29:1671–1673.

    PubMed  CAS  Google Scholar 

  10. Sánchez E, Gómez LM, Lopez-Nevot MA, et al.: Evidence of association of macrophage migration inhibitory factor gene polymorphisms with systemic lupus erythematosus. Genes Immun 2006, 7:433–436.

    Article  PubMed  Google Scholar 

  11. Wu SP, Leng L, Feng Z, et al.: Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma. Arthritis Rheum 2006, 54:3661–3669.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Medicine and Pathology, Yale University School of Medicine, The Anlyan Center, S525, 300 Cedar Street, New Haven, CT, 06520-8031, USA

    Richard Bucala

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  1. Timothy R. D. J. Radstake
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  2. Richard Bucala
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Correspondence to Richard Bucala.

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Radstake, T.R.D.J., Bucala, R. Macrophage migration inhibitory factor and its genetic association with arthritis: A work in progress. Curr Rheumatol Rep 9, 343–344 (2007). https://doi.org/10.1007/s11926-007-0054-6

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  • DOI: https://doi.org/10.1007/s11926-007-0054-6

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