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Biocompatibility and antibacterial performance of titanium by surface treatment

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Abstract

Titanium (Ti) and its alloys are used extensively in implants due to their excellent biocompatibility and mechanical properties. However, Ti-based implant materials have specific complications associated with their applications, such as the loosening of implanted host interface owing to unsatisfactory cell adhesion and the susceptibility of the implants to bacterial infections. Hence, a surface that displays selective biointeractivity, i.e., enhancing beneficial host cell responses but inhibiting pathogenic microbial adhesion, would be highly desirable. This study aims to confer long-lasting antibacterial properties and good biocompatibility on Ti via the microarc oxidation technique. The biocompatibility of the Ti surface was evaluated by cytotoxicity test, and the bacteriostasis rate was evaluated by antibacterial efficacy. The results showed that the implant surface might be nontoxic to cell and its long-lasting antibacterial properties could be significantly improved. These results indicate that such microarc oxidation coatings are expected to have good potential in transcutaneous implant applications.

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Acknowledgments

This work was supported by the State Key Program of National Natural Science of China; grant number: 30630066. The authors gratefully thank the State Key Laboratory for Mechanical Behavior of Materials at Xi’an Jiaotong University and Tissue Engineering Center (Fourth Military Medical University) in China for the research support.

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  1. Department of Prosthodontics, College of Stomatology, Fourth Military Medical University, Xi’an, 710032, Shaanxi, People’s Republic of China

    Jianxue Li & Yimin Zhao

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  1. Jianxue Li
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  2. Yimin Zhao
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Correspondence to Yimin Zhao.

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Li, J., Zhao, Y. Biocompatibility and antibacterial performance of titanium by surface treatment. J Coat Technol Res 9, 223–228 (2012). https://doi.org/10.1007/s11998-009-9221-1

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  • DOI: https://doi.org/10.1007/s11998-009-9221-1

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