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Bioactivity and mechanical behaviour of cobalt oxide-doped bioactive glass

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Abstract

Bioactive glasses are materials capable of bonding implants to tissues. 45S5 Bio-glass ® is one such material capable of bonding strongly to bone within 6 weeks. It develops a hydroxy-carbonate apatite layer on the implant that is chemically and crystallographically equivalent to the mineral phase of bone. However, it suffers from a mechanical weakness and low fracture toughness due to an amorphous glass network and is not suitable for load-bearing applications. In order to improve its mechanical strength and bioactivity, the present work explores the effects of cobalt oxide additions. Bioactivity of the glass samples was assessed through their hydroxyapatite formation ability by immersing them in the simulated body fluid for different soaking periods. The formation of hydroxyapatite was confirmed by Fourier transform infrared spectrometry, pH measurement and microstructure evaluation through scanning electron microscopy. Densities and mechanical properties of the samples were found to increase considerably with an increase in the concentration of cobalt oxide.

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Acknowledgements

We gratefully acknowledge the HOD, Department of Ceramic Engineering, Indian Institute of Technology (Banaras Hindu University), Varanasi 221 005, India, the honorable Director of Indian Institute of Technology (Banaras Hindu University), Varanasi, India, for providing necessary facilities for the present work.

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Authors and Affiliations

  1. Department of Ceramic Engineering, Indian Institute of Technology (Banaras Hindu University), Varanasi, 221 005, India

    VIKASH KUMAR VYAS, AREPALLI SAMPATH KUMAR, SUNIL PRASAD, S P SINGH & RAM PYARE

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  1. VIKASH KUMAR VYAS
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  2. AREPALLI SAMPATH KUMAR
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Correspondence to VIKASH KUMAR VYAS.

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VYAS, V.K., KUMAR, A.S., PRASAD, S. et al. Bioactivity and mechanical behaviour of cobalt oxide-doped bioactive glass. Bull Mater Sci 38, 957–964 (2015). https://doi.org/10.1007/s12034-015-0936-6

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