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Synthesis and antibacterial activity of sulfonamide derivatives at C-8 alkyl chain of anacardic acid mixture isolated from a natural product cashew nut shell liquid (CNSL)

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Abstract

Synthesis and antibacterial activity of some novel biologically active sulfonamide derivatives at C-8 alkyl chain of anacardic acid (7a–7l), prepared from commercially available anacardic acid mixture (1a–d). These compounds were tested for Gram positive and Gram negative bacterial cultures; most of the compounds showed higher antibacterial activity compared with standard drug ampicillin.

Synthesis and antibacterial activity of some novel biologically active sulfonamide derivatives at C-8 alkyl chain of anacardic acid (7a–7l), prepared from commercially available anacardic acid mixture (1a–d). Compounds (7a–7l) were tested for Gram positive and Gram negative bacterial cultures; most of the compounds showed a higher antibacterial activity compared with standard drug ampicillin.

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References

  1. Tyman J H P 1979 Chem. Soc. Rev. 8 499

    Article  CAS  Google Scholar 

  2. Kubo I, Muroi H, Himejima M and Yamigiwa Y 1993 J. Agric. Food Chem. 41 1016

    Article  CAS  Google Scholar 

  3. Gillerman J L, Walsh N J, Werner N K and Schlenk H 1969 Can. J. Microbiol. 15 1219

    Article  Google Scholar 

  4. Shoba S V, Ramadoss C S and Ravindranath B 1994 J. Nat. Prod. 57 1755

    Article  Google Scholar 

  5. Ha T J and Kubo I 2005 J. Agric. Food Chem. 53 4350

    Article  CAS  Google Scholar 

  6. Chandregowda V, Kush A and Reddy G 2009 Eur. J. Med. Chem. 44 2711

    Article  CAS  Google Scholar 

  7. Paramashivappa R, Phanikumar P, Subba Rao P V and Srinivasa Rao A 2002 J. Agric. Food Chem. 50 7709

    Article  CAS  Google Scholar 

  8. Phanikumar P, Stotz S C, Paramashivappa R, Beedle M, Zamponi G W and Srinivasa Rao A 2002 Mol. Pharmacol. 61 649

    Article  Google Scholar 

  9. Narayana Swamy B, Suma T K, Venkateswara Rao G and Chandrasekara Reddy G 2007 Eur. J. Med. Chem. 42 422

    Google Scholar 

  10. Kubo I, Ochi M, Viera P C and Komatsu S 1993 J. Agric. Food Chem. 41 1012

    Article  CAS  Google Scholar 

  11. Mantelingu K, Kishore A H, Balasubramanyam K, Kumar G V, Altaf M, Swamy S N, Selvi R, Das C, Narayana C, Rangappa K S and Kundu T K 2007 J. Phys. Chem. B 111 4527

    Article  CAS  Google Scholar 

  12. Hari Kishore A, Vedamurthy B M, Mantelingu K, Agrawal S, Ashok Reddy B A, Roy S, Rangappa K S and Kundu T K 2008 J. Med. Chem. 51 792

    Article  Google Scholar 

  13. Sung B, Pandey M K, Ahn K S, Yi T, Chaturvedi M M, Liu M and Aggarwal B 2008 Blood 111 4880

    Article  CAS  Google Scholar 

  14. Cui L, Miao J, Furuya T, Fan Q, Li X, Rathod P K, Su X Z and Cui L 2008 Eukaryotic Cell 7 1200

    Article  CAS  Google Scholar 

  15. Sbardella G, Castellano S, Vicidomini C, Rotili D, Nebbioso A, Miceli M, Altucci L and Mai A 2008 Bioorg. Med. Chem. Lett. 18 2788

    Article  CAS  Google Scholar 

  16. Rybak M J and Akins R L 2001 Drugs 61, 1

    Article  CAS  Google Scholar 

  17. Lipsitch M 2001 Trends Microbiol. 9 438

    Article  CAS  Google Scholar 

  18. Cunha B A 1998 Drugs Today 34 691

    CAS  Google Scholar 

  19. Marchese A, Schito G C and Debbia E A 2000 J. Chemother., (Firenze) 12 459

    CAS  Google Scholar 

  20. Cetinkaya Y, Falk P and Mayhall C G 2000 Clin. Microbiol. Rev. 13 686

    Article  CAS  Google Scholar 

  21. Cassell G H and Mekalanos J 2001 J. Am. Med. Assoc. 285 601

    Article  CAS  Google Scholar 

  22. Chu D T W, Plattner J J and Katz L 1996 J. Med. Chem. 39 3853

    Article  CAS  Google Scholar 

  23. Gulati A S and Subba Rao B C 1964 Indian J. Chem. 2 337

    CAS  Google Scholar 

  24. EI Sholy M A, Adawadkar P D, Benigni D A, Watson E S and Little T L Jr. 1986 J. Med. Chem. 29 606

    Article  Google Scholar 

  25. (a) Dos Santos M L and de Magalhães G C 1993 Quim Nova, 16, 534; (b) Carvalho M G, Braz-Filho R, Dos Santos M L and de Magalhães G C 1993 J. Braz. Chem. Soc. 4 158; (c) Dos Santos M L and de Magalhães 1999 J. Braz. Chem. Soc. 10 13; (d) Lúcio P L Logrado, Dâmaris Silveira, Luiz A S Romeiro, Manoel O de Moraes, Bruno C Cavalcanti, Letícia V Costa-Lotufo, Cláudia do Ó Pessoa and Maria Lucilia dos Santos 2005 J. Braz. Chem. Soc. 16 1217

  26. (a) Kiong L S and Tyman J H P 1981 J. Chem. Soc. Perkin Trans. 1 1942; (b) Paramashivappa R, Phanikumar P, Vithayathil P J and Srinivasa Rao A 2001 J. Agric. Food Chem. 49 2548

  27. Rahman A, Choudhary M I and Thomsen W J 2001 Bioassay techniques for drug development (The Netherlands: Harwood Academic Publishers) pp. 16

    Book  Google Scholar 

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Authors and Affiliations

  1. Medicinal chemistry Laboratory, GVK Biosciences Pvt Ltd, Plot No 5C, IDA, Uppal Road, Hyderabad, 500 039, India

    N SUBHAKARA REDDY, A SRINIVAS RAO & V RAVI KUMAR

  2. Centre for Environment, Institute of Science and Technology, JNT University, Kukatpally, Hyderabad, 500 085, India

    N SUBHAKARA REDDY & V HIMABINDU

  3. Dr. MACS Bio-Pharma Pvt. Ltd., Plot-32/A,Westren Hills, Kukatpally, Hyderabad, 500 085, India

    M ADHARVANA CHARI & V JYOTHY

  4. Department of Complexity Science and Engineering, School of Frontier Sciences, 5-1-5, Kashiwanoha, Kashiwa, University of Tokyo, Chiba, 277 8561, Japan

    M ADHARVANA CHARI

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  1. N SUBHAKARA REDDY
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  2. A SRINIVAS RAO
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  3. M ADHARVANA CHARI
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  4. V RAVI KUMAR
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  5. V JYOTHY
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  6. V HIMABINDU
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Correspondence to M ADHARVANA CHARI.

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REDDY, N.S., RAO, A.S., CHARI, M.A. et al. Synthesis and antibacterial activity of sulfonamide derivatives at C-8 alkyl chain of anacardic acid mixture isolated from a natural product cashew nut shell liquid (CNSL). J Chem Sci 124, 723–730 (2012). https://doi.org/10.1007/s12039-012-0253-1

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  • DOI: https://doi.org/10.1007/s12039-012-0253-1

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