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Treatment of peritoneal carcinomatosis from ovarian cancer. Present, future directions and proposals

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Abstract

Peritoneal carcinomatosis, considered years ago as a final stage of unresectable cancer, can now be managed with curative intention by means of a radical cytoreductive surgical procedure with associated peritonectomy and intraperitoneal chemotherapy, as described by Sugarbaker. Malignant neoplasms such as mesothelioma and pseudomyxoma peritonei, ovarian and colon cancer nowadays are experiencing some new therapeutical approaches. Higher survival rates can be reached in ovarian cancer, which is commonly diagnosed in the presence of peritoneal carcinomatosis, using an optimal cytoreductive radical surgery with intraperitoneal chemotherapy. An actualised review of the treatment of advanced ovarian cancer and a proposal of a national multicentre protocol for the treatment of peritoneal carcinomatosis from ovarian cancer has been performed by a group of Spanish surgeons and oncologists dedicated to a therapeutical approach to this pathology.

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Authors and Affiliations

  1. Department of Surgery, Unit of Oncological Surgery Reina Sofía University Hospital, Avda. Menéndez Pidal, s/n, 14004, Córdoba, Spain

    F. C. Muñoz-Casares, S. Rufián, M. J. Rubio, E. Lizárraga, C. Díaz-Iglesias, E. Aranda, R. Ciria & J. Muntané

  2. Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

    P. Barrios

  3. Hospital de Torrecárdenas, Almería, Spain

    J. Torres-Melero

  4. Centro Oncológico MD Anderson International España, Madrid, Spain

    S. González-Moreno

  5. Hospital General Universitario Gregorio Marañón, Madrid, Spain

    L. González-Bayón

  6. Hospital Clínico Universitario, Valencia, Spain

    B. Camps

  7. Hospital San Jaime, Alicante, Spain

    P. Bretcha & J. Farré

  8. Hospital de Fuenlabrada, Madrid, Spain

    G. Ortega-Pérez

  9. Policlínica San José, Vitoria, Spain

    A. Gómez-Portilla

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  1. F. C. Muñoz-Casares
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Muñoz-Casares, F.C., Rufián, S., Rubio, M.J. et al. Treatment of peritoneal carcinomatosis from ovarian cancer. Present, future directions and proposals. Clin Transl Oncol 9, 652–662 (2007). https://doi.org/10.1007/s12094-007-0118-0

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