Skip to main content
Log in

Levels, Distributions and Health Risk Assessment of Lead, Cadmium and Arsenic Found in Drinking Groundwater of Dehgolan’s Villages, Iran

  • Published:
Toxicology and Environmental Health Sciences Aims and scope Submit manuscript

Abstract

Objective

Water contamination by heavy metals has become a serious environmental issue due to its serious threat to human health. The current research was conducted to determine heavy metal concentrations in drinking groundwater samples in villages of Dehgolan, western Iran and to ascertain the potential health risk in terms of estimated non-carcinogenic risks by hazard quotient and hazard index and carcinogenic risk to the residents living in these areas from exposure to the metals via drinking water ingestion and skin contact routes.

Methods

Health risks were conducted for resident adults based on the USEPA health risk assessment guidelines.

Results

The mean values of Pb, Cd, and As in the groundwater samples were 0.0026 mg/L (ranging from 0.0020–0.0030 mg/L), 0.0009 mg/L (ranging from 0.0007–0.0010 mg/L), and 0.0068 mg/L (ranging from 0.0011–0.0360 mg/L), respectively. Compared to the WHO drinking water guidelines for Pb, Cd and As, virtually all the trace elements in the drinking water of villages in the present study could meet the requirements of the regulation except As in some villages.

Conclusion

The results of the study obtained in all cases demonstrated that the non-carcinogenic risk was below the safe limit. The calculated carcinogenic risk for adults obtained was all lower than USEPA’s acceptable cancer risk range of 1 × 10−4 to 1 × 10−6, suggesting no potential carcinogenic risk from drinking water consumption.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Khosravi, R. et al. Use of geographic information system and water quality index to assess groundwater quality for drinking purpose in Birjand City, Iran. Desalin. Water Treat. 67, 74–83 (2017).

    Article  CAS  Google Scholar 

  2. Masoudinejad, M. et al. Data on phosphorous concentration of rivers feeding into Taham dam in Zanjan, Iran. Data Brief 17, 564–569 (2018).

    Article  PubMed  PubMed Central  Google Scholar 

  3. Derakhshani, E. et al. Association of toxicochemical and microbiological quality of bottled mineral water in Birjand city, Iran. Toxin Rev. 37, 138–143 (2018).

    Article  CAS  Google Scholar 

  4. Dehghani, M., Farhang, M. & Zarei, A. Investigation of carbonyl compounds (acetaldehyde and formaldehyde) in bottled waters in Iranian markets. Int. Food Res. J. 25, 876–879 (2018).

    CAS  Google Scholar 

  5. Jafari, A., Kamarehie, B., Ghaderpoori, M., Khosh-namvand, N. & Birjandi, M. The concentration data of heavy metals in Iranian grown and imported rice and human health hazard assessment. Data Brief 16, 453–459 (2018).

    Article  Google Scholar 

  6. Khaniki, G. J., Ghaderpoori, M., Dehghani, M. H. & Nazmara, S. Analysis of toxic and trace metal contaminants in bottled water by using atomic absorption spectrometry. Food Environ. Safe. J. 10, 78–83 (2017).

    Google Scholar 

  7. Muhammad, S., Shah, M. T. & Khan, S. Health risk assessment of heavy metals and their source apportionment in drinking water of Kohistan region, northern Pakistan. Microchem. J. 98, 334–343 (2011).

    Article  CAS  Google Scholar 

  8. Singh, R., Gautam, N., Mishra, A. & Gupta, R. Heavy metals and living systems: An overview. Indian J. Pharmacol. 43, 246 (2011).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Ekpo, K., Asia, I., Amayo, K. & Jegede, D. Determination of lead, cadmium and mercury in surrounding water and organs of some species of fish from Ikpoba river in Benin city, Nigeria. Int. J. Phys. Sci. 3, 289–292 (2008).

    Google Scholar 

  10. Gbadamosi, M. et al. Distribution of radionuclides and heavy metals in the bituminous sand deposit in Ogun State, Nigeria—A multi-dimensional pollution, health and radiological risk assessment. J. Geochem. Explor. 190, 187–199 (2018).

    Article  CAS  Google Scholar 

  11. Bhattacharya, B. D. et al. Bioaccumulation of trace elements in dominant mesozooplankton group inhabiting in the coastal regions of Indian Sundarban mangrove wetland. Mar. Pollut. Bull. 87, 345–351 (2014).

    Article  CAS  PubMed  Google Scholar 

  12. Wu, C., Zhu, H., Luo, Y. & Wang, J. Concentrations and potential health hazards of polycyclic aromatic hydrocarbon in shallow groundwater of a metal smelting area in Southeastern China. Sci. Total Environ. 569, 1561–1569 (2016).

    Article  CAS  PubMed  Google Scholar 

  13. Vodela, J., Renden, J., Lenz, S., McElhenney, W. & Kemppainen, B. Drinking water contaminants (arsenic, cadmium, lead, benzene, and trichloroethylene). 1. Interaction of contaminants with nutritional status on general performance and immune function in broiler chickens. Poult. Sci. 76, 1474–1492 (1997).

    Article  CAS  PubMed  Google Scholar 

  14. Ferrante, M. et al. Groundwater-based water wells characterization from Guinea Bissau (Western Africa): A risk evaluation for the local population. Sci. Total Environ. 619, 916–926 (2018).

    Article  CAS  PubMed  Google Scholar 

  15. Sun, H., Cheng, H., Lin, L., Deng, K. & Cui, X. Bioaccumulation and sources of metal (loid) s in lilies and their potential health risks. Ecotoxicol. Environ. Safe. 151, 228–235 (2018).

    Article  CAS  Google Scholar 

  16. Esmaeilzadeh, M. et al. Investigation of the extent of contamination of heavy metals in agricultural soil using statistical analyses and contamination indices. Hum. Ecol. Risk Assess. 24, 1–12 (2018).

    Article  CAS  Google Scholar 

  17. Saleh, H. N. et al. Carcinogenic and Non-carcinogenic Risk Assessment of Heavy Metals in Groundwater Wells in Neyshabur Plain, Iran. Biol. Trace Elem. Res. 14, 1–11 (2018).

    Google Scholar 

  18. Yousefi, M., Ghoochani, M. & Mahvi, A. H. Health risk assessment to fluoride in drinking water of rural residents living in the Poldasht city, Northwest of Iran. Ecotoxicol. Environ. Safe. 148, 426–430 (2018).

    Article  CAS  Google Scholar 

  19. Mehrizi, E. et al. Determine the important heavy metals in air dust of zahedan, Iran. Pollut. Res. 36, 474–480 (2017).

    CAS  Google Scholar 

  20. Zhang, A. et al. Association between prenatal lead exposure and blood pressure in children. Environ. Health Perspect. 120, 445–450 (2011).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Mortada, W., Sobh, M., El-Defrawy, M. & Farahat, S. Study of lead exposure from automobile exhaust as a risk for nephrotoxicity among traffic policemen. Am. J. Nephrol. 21, 274–279 (2001).

    Article  CAS  PubMed  Google Scholar 

  22. Kavcar, P., Sofuoglu, A. & Sofuoglu, S. C. A health risk assessment for exposure to trace metals via drinking water ingestion pathway. Int. J. Hyg. Environ. Health 212, 216–227 (2009).

    Article  CAS  PubMed  Google Scholar 

  23. Rom, W. N. & Markowitz, S. B. Environmental and occupational medicine. (Lippincott Williams & Wilkins, 2007).

  24. Arao, T., Kawasaki, A., Baba, K., Mori, S. & Matsumoto, S. Effects of water management on cadmium and arsenic accumulation and dimethylarsinic acid concentrations in Japanese rice. Environ. Sci. Technol. 43, 9361–9367 (2009).

    Article  CAS  PubMed  Google Scholar 

  25. Satarug, S. et al. A global perspective on cadmium pollution and toxicity in non-occupationally exposed population. Toxicol. Lett. 137, 65–83 (2003).

    Article  CAS  PubMed  Google Scholar 

  26. Baghvand, A. et al. Groundwater quality degradation of an aquifer in Iran central desert. Desalination 260, 264–275 (2010).

    Article  CAS  Google Scholar 

  27. Balkhair, K. S. & Ashraf, M. A. Field accumulation risks of heavy metals in soil and vegetable crop irrigated with sewage water in western region of Saudi Arabia. Saudi J. Biol. Sci. 23, S32–S44 (2016).

    Article  CAS  PubMed  Google Scholar 

  28. Baghani, A. N. et al. BTEX in indoor air of beauty salons: Risk assessment, levels and factors influencing their concentrations. Ecotoxicol. Environ. Safe. 159, 102–108 (2018).

    Article  CAS  Google Scholar 

  29. Hazrati, S., Rostami, R., Farjaminezhad, M. & Fazlzadeh, M. Preliminary assessment of BTEX concentrations in indoor air of residential buildings and atmospheric ambient air in Ardabil, Iran. Atmos. Environ. 132, 91–97 (2016).

    Article  CAS  Google Scholar 

  30. Dehghani, M. et al. Characteristics and health effects of BTEX in a hot spot for urban pollution. Ecotoxicol. Environ. Safe. 155, 133–143 (2018).

    Article  CAS  Google Scholar 

  31. Hazrati, S., Rostami, R., Fazlzadeh, M. & Pourfarzi, F. Benzene, toluene, ethylbenzene and xylene concentrations in atmospheric ambient air of gasoline and CNG refueling stations. Air Qual. Atmos. Hlth. 9, 403–409 (2016).

    Article  CAS  Google Scholar 

  32. Fu, Q.L., Li, L., Achal, V., Jiao, A.-Y. & Liu, Y. Concentrations of heavy metals and arsenic in market rice grain and their potential health risks to the population of Fuzhou, China. Hum. Ecol. Risk Assess. 21, 117–128 (2015).

    Article  CAS  Google Scholar 

  33. Achary, M. S., Panigrahi, S., Satpathy, K., Prabhu, R. & Panigrahy, R. Health risk assessment and seasonal distribution of dissolved trace metals in surface waters of Kalpakkam, southwest coast of Bay of Bengal. Reg. Stud. Mar. Sci. 6, 96–108 (2016).

    Article  Google Scholar 

  34. Keramati, H. et al. Radon 222 in drinking water resources of Iran: A systematic review, meta-analysis and probabilistic risk assessment (Monte Carlo simulation). Food Chem. Toxicol. 115, 460–469 (2018).

    Article  CAS  PubMed  Google Scholar 

  35. Qasemi, M., Afsharnia, M., Zarei, A., Farhang, M. & Allahdadi, M. Non-carcinogenic risk assessment to human health due to intake of fluoride in the groundwater in rural areas of Gonabad and Bajestan, Iran: A case study. Hum. Ecol. Risk Assess. 24, 1–12 (2018).

    Article  CAS  Google Scholar 

  36. Asare, M. L., Cobbina, S. J., Akpabey, F. J., Duwiejuah, A. B. & Abuntori, Z. N. Heavy Metal Concentration in Water, Sediment and Fish Species in the Bontanga Reservoir, Ghana. Toxicol. Environ. Health Sci. 10, 49–58 (2018).

    Article  Google Scholar 

  37. Iqbal, J., Shah, M. H. & Akhter, G. Characterization, source apportionment and health risk assessment of trace metals in freshwater Rawal Lake, Pakistan. J. Geochem. Explor. 125, 94–101 (2013).

    Article  CAS  Google Scholar 

  38. Schwab, B. W. et al. Human pharmaceuticals in US surface waters: a human health risk assessment. Regul. Toxicol. Pharmacol. 42, 296–312 (2005).

    Article  CAS  PubMed  Google Scholar 

  39. Mirzabeygi, M. et al. The concentration data of fluoride and health risk assessment in drinking water in the Ardakan city of Yazd province, Iran. Data Brief 18, 40–46 (2018).

    Article  Google Scholar 

  40. Ghaderpoori, M. et al. Health risk assessment of fluoride in water distribution network of Mashhad, Iran. Hum. Ecol. Risk Assess. 24, 1–12 (2018).

    Article  CAS  Google Scholar 

  41. Qasemi, M. et al. Health risk assessment of nitrate exposure in groundwater of rural areas of Gonabad and Bajestan, Iran. Environ. Earth Sci. 77, 551 (2018).

    Article  CAS  Google Scholar 

  42. Kazi, T. G. et al. The effects of arsenic contaminated drinking water of livestock on its total levels in milk samples of different cattle: Risk assessment in children. Chemosphere 165, 427–433 (2016).

    Article  CAS  PubMed  Google Scholar 

  43. Sohrabi, Y. et al. Heavy metal concentrations in water resources of rural areas of Kermanshah, Iran. Lioab J. 7, 542–546 (2016).

    Google Scholar 

  44. Liu, X. et al. Human health risk assessment of heavy metals in soil — vegetable system: a multi-medium analysis. Sci. Total Environ. 463, 530–540 (2013).

    Article  CAS  PubMed  Google Scholar 

  45. Iqbal, J. & Shah, M. H. Study of seasonal variations and health risk assessment of heavy metals in Cyprinus carpio from Rawal Lake, Pakistan. Environ. Monit. Assess. 186, 2025–2037 (2014).

    Article  CAS  PubMed  Google Scholar 

  46. Kamani, H. et al. Concentration and ecological risk of heavy metal in street dusts of Eslamshahr, Iran. Hum. Ecol. Risk Assess. 24, 961–970 (2018).

    Article  CAS  Google Scholar 

  47. Ghaderpoori, M., Kamarehie, B., Jafari, A., Ghaderpoury, A. & Karami, M. A. Heavy metals analysis and quality assessment in drinking water-Khorramabad city, Iran. Data Brief 16, 658–692 (2018).

    Article  Google Scholar 

  48. Chanpiwat, P., Lee, B. T., Kim, K. W. & Sthiannopkao, S. Human health risk assessment for ingestion exposure to groundwater contaminated by naturally occurring mixtures of toxic heavy metals in the Lao PDR. Environ. Monit. Assess. 186, 4905–4923 (2014).

    Article  CAS  PubMed  Google Scholar 

  49. Dehghani, M. H., Farhang, M., Alimohammadi, M., Afsharnia, M. & Mckay, G. Adsorptive removal of fluoride from water by activated carbon derived from CaCl2-modified Crocus sativus leaves: Equilibrium adsorption isotherms, optimization, and influence of anions. Chem. Eng. Commun. 205, 955–965 (2018).

    Article  CAS  Google Scholar 

  50. Mohammadi, M. J. et al. A health risk assessment of heavy metals in people consuming Sohan in Qom, Iran. Toxin Rev. 37, 278–286 (2018).

    Article  CAS  Google Scholar 

  51. Qasemi, M. et al. Data on cadmium removal from synthetic aqueous solution using garbage ash. Data Brief 20, 1115–1123 (2018).

    Article  PubMed  PubMed Central  Google Scholar 

  52. Malakootian, M. & Khashi, Z. Heavy metals contamination of drinking water supplies in southeastern villages of Rafsanjan plain: Survey of arsenic, cadmium, lead and copper. J. Health Field 2, 1–10 (2014).

    Google Scholar 

  53. Kohzadi, S., Shahmoradi, B., Raushani, D. & Nouri, A. Evaluation and Risk Assessment of Heavy Metals in the Groundwater Resources of Saqqez, Iran. J. Environ. Health 80, E1–E9 (2018).

    Google Scholar 

  54. Reuer, M. K. et al. Lead, arsenic, and cadmium contamination and its impact on children’s health in La Oroya, Peru. ISRN Public Health 2012, 1–12 (2011).

    Article  Google Scholar 

  55. Harmanescu, M., Alda, L. M., Bordean, D. M., Gogoasa, I. & Gergen, I. Heavy metals health risk assessment for population via consumption of vegetables grown in old mining area; a case study: Banat County, Romania. Chem. Cent. J. 5, 64 (2011).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  56. Jaishankar, M., Tseten, T., Anbalagan, N., Mathew, B. B. & Beeregowda, K. N. Toxicity, mechanism and health effects of some heavy metals. Interdisciplinary Toxicol. 7, 60–72 (2014).

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The authors would like to thank Professor Mehdi Zarrei in Hospital for Sick Children in Toronto, Canada for valuable comments and suggestions, allowing us to improve this paper.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mansour Ghaderpoori.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rezaei, H., Zarei, A., Kamarehie, B. et al. Levels, Distributions and Health Risk Assessment of Lead, Cadmium and Arsenic Found in Drinking Groundwater of Dehgolan’s Villages, Iran. Toxicol. Environ. Health Sci. 11, 54–62 (2019). https://doi.org/10.1007/s13530-019-0388-2

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13530-019-0388-2

Keywords

Navigation