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Thermal Characteristics, Mechanical Properties, In Vitro Degradation and Cytotoxicity of Novel Biodegradable Zn–Al–Mg and Zn–Al–Mg–xBi Alloys

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Acta Metallurgica Sinica (English Letters) Aims and scope

Abstract

Ternary Zn–0.5Al–0.5Mg and quaternary Zn–0.5Al–0.5Mg–xBi (x = 0.1, 0.3 and 0.5) alloys were studied to evaluate the thermal and structural characteristics, mechanical properties, cytotoxicity and in vitro degradation behavior. Thermal analysis and microstructural observations showed that Zn–0.5Al–0.5Mg is composed of FCC-Al + HCP-Zn + Mg2(Zn,Al)11 while a new phase α-Mg3Bi2 appeared after the addition of Bi to the Zn–0.5Al–0.5Mg ternary alloy. The results revealed that the quaternary Zn–Al–Mg–Bi alloys have higher tensile strength, elongation and hardness but slightly lower corrosion resistance than those of the ternary Zn–Al–Mg alloy. Based on the MTT assay, the Zn–Al–Mg and Zn–Al–Mg–Bi alloys were found to be biocompatible, and thus, they can be considered for further investigation in an in vivo environment.

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Acknowledgements

The authors thank the Malaysian Ministry of Higher Education (MOHE) and Universiti Teknologi Malaysia for providing the facilities for this research.

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Authors and Affiliations

  1. Advanced Materials Research Center, Department of Materials Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran

    H. R. Bakhsheshi-Rad & M. Kasiri-Asgarani

  2. Department of Materials, Manufacturing and Industrial Engineering, Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, 81310, Johor Bahru, Johor, Malaysia

    E. Hamzah & H. T. Low

  3. Research and Development Centre, KISWIRE Sdn. Bhd, Johor Bahru, Johor, Malaysia

    M. H. Cho

  4. Department of Materials and Mechanical Engineering, Buein Zahra Technical University, Qazvin, 3451745346, Iran

    S. Farahany

  5. Department of Mechanical and Materials Engineering, Masdar Institute of Science and Technology, P. O. Box: 54224, Masdar City, Abu Dhabi, UAE

    A. Mostafa & M. Medraj

  6. Department of Mechanical Engineering, Concordia University, 1455 De Maisonneuve Blvd. West, Montreal, QC, H3G 1M8, Canada

    M. Medraj

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  1. H. R. Bakhsheshi-Rad
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  2. E. Hamzah
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  3. H. T. Low
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  4. M. H. Cho
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  5. M. Kasiri-Asgarani
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  6. S. Farahany
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  7. A. Mostafa
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Correspondence to H. R. Bakhsheshi-Rad.

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Bakhsheshi-Rad, H.R., Hamzah, E., Low, H.T. et al. Thermal Characteristics, Mechanical Properties, In Vitro Degradation and Cytotoxicity of Novel Biodegradable Zn–Al–Mg and Zn–Al–Mg–xBi Alloys. Acta Metall. Sin. (Engl. Lett.) 30, 201–211 (2017). https://doi.org/10.1007/s40195-017-0534-2

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  • DOI: https://doi.org/10.1007/s40195-017-0534-2

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