Zusammenfassung
Säure-Basen-Störungen und insbesondere die metabolische Azidose sind sehr häufig bei kritisch kranken Patienten und tragen wesentlich zur Morbidität und Sterblichkeit bei. Es werden die häufigsten Ursachen, die Pathophysiologie und Therapien beleuchtet, wobei ein besonderes Augenmerk auf die häufig geübte Praxis der Substitution von Natriumbikarbonat in Anbetracht neuerer Studienergebnisse gelegt wird.
Abstract
Acid–base disorders and in particular metabolic acidosis are very common in critically ill patients and contribute significantly to morbidity and mortality. We shed light on the most common causes, the pathophysiology and treatments. Particular attention will be paid to the common practice of substituting sodium bicarbonate in the light of recent study results.
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19 August 2020
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S. Schricker und M. Schanz geben an, dass kein Interessenkonflikt besteht. M. D. Alscher hat Vortragshonorare von Fresenius Medical Care und Baxter außerhalb des vorliegenden Artikels erhalten. M. Kimmel hat Vortragshonorare von Fresenius Medical Care, Baxter und Vifor außerhalb des vorliegenden Artikels erhalten.
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Schricker, S., Schanz, M., Alscher, M.D. et al. Metabolische Azidose. Med Klin Intensivmed Notfmed 115, 275–280 (2020). https://doi.org/10.1007/s00063-019-0538-y
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DOI: https://doi.org/10.1007/s00063-019-0538-y